ADE3/YGR204W Literature Guide Help

Other names published for ADE3: trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase ADE3, YGR204W

ADE3 - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Alabrudzinska M, et al.  (2011) Dipoid-Specific Genome Stability Genes of S. cerevisiae: Genomic Screen Reveals Haploidization as an Escape from Persisting DNA Rearrangement Stress. PLoS One 6(6):e21124
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Hurlimann HC, et al.  (2011) Physiological and toxic effects of purine intermediate 5-amino-4-imidazolecarboxamide ribonucleotide (AICAR) in yeast. J Biol Chem 286(35):30994-1002
Matecic M, et al.  (2010) A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet 6(4):e1000921
Joo YJ, et al.  (2009) Cooperative regulation of ADE3 transcription by Gcn4p and Bas1p in Saccharomyces cerevisiae. Eukaryot Cell 8(8):1268-77
Freimoser FM, et al.  (2006) Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol 7(11):R109
Rebora K, et al.  (2005) Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule. Genetics 170(1):61-70
Stepchenkova EI, et al.  (2005) Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast. BMC Genet 6():31
Koren A, et al.  (2003) Pitfalls of the synthetic lethality screen in Saccharomyces cerevisiae: an improved design. Curr Genet 43(1):62-9
Yang Y and Meier UT  (2003) Genetic interaction between a chaperone of small nucleolar ribonucleoprotein particles and cytosolic serine hydroxymethyltransferase. J Biol Chem 278(26):23553-60
McNeil JB, et al.  (1996) In vivo analysis of folate coenzymes and their compartmentation in Saccharomyces cerevisiae. Genetics 142(2):371-81
West MG, et al.  (1996) Metabolic role of cytoplasmic isozymes of 5,10-methylenetetrahydrofolate dehydrogenase in Saccharomyces cerevisiae. Biochemistry 35(9):3122-32
Sinclair DA and Dawes IW  (1995) Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Genetics 140(4):1213-22
Song JM and Rabinowitz JC  (1995) The N-terminal, dehydrogenase/cyclohydrolase domain of yeast cytoplasmic trifunctional C1-tetrahydrofolate synthase requires the C-terminal, synthetase domain for the catalytic activity in vitro. FEBS Lett 376(3):229-32
Song JM and Rabinowitz JC  (1993) Function of yeast cytoplasmic C1-tetrahydrofolate synthase. Proc Natl Acad Sci U S A 90(7):2636-40
Barlowe CK and Appling DR  (1990) Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme. Mol Cell Biol 10(11):5679-87
Barlowe CK and Appling DR  (1989) A general method for generation and analysis of defined mutations in enzymes involved in a tetrahydrofolate-interconversion pathway. Biofactors 2(1):57-63
Barlowe CK, et al.  (1989) Site-directed mutagenesis of yeast C1-tetrahydrofolate synthase: analysis of an overlapping active site in a multifunctional enzyme. Biochemistry 28(5):2099-106
de Mata ZS and Rabinowitz JC  (1980) Formyl-methenyl-methylenetetrahydrofolate synthetase(combined) from yeast. Biochemical characterization of the protein from an ade3 mutant lacking the formyltetrahydrofolate synthetase function. J Biol Chem 255(6):2569-77
Jones EW  (1977) Bipartite structure of the ade3 locus of Saccharomyces cerevisiae. Genetics 85(2):209-23
McKenzie KQ and Jones EW  (1977) Mutants of formyltetrahydrofolate interconversion pathway of Saccharomyces cerevisiae. Genetics 86(1):85-102
Zelikson R and Luzzati M  (1977) Mitochondrial and cytoplasmic distribution in Saccharmoyces cerevisiae of enzymes involved in folate-coenzyme-mediated one-carbon-group transfer. A genetic and biochemical study of the enzyme deficiencies in mutants tmp3 and ade3. Eur J Biochem 79(1):285-92
Zelikson R and Luzzati M  (1976) Two forms of serine transhydroxymethylase, one absent in a thymidylate-less mutant in Saccharomyces cerevisiae. Eur J Biochem 64(1):7-13
Jones EW and Lam KB  (1973) Mutations affecting levels of tetrahydrofolate interconversion enzymes in Saccharomyces cerevisiae. II. Map positions on chromosome VII of ade3-41 and ADE15. Mol Gen Genet 123(3):209-18
Lam KB and Jones EW  (1973) Mutations affecting levels of tetrahydrofolate interconversion enzymes in Saccharomyces cerevisiae. I. Enzyme levels in ade3-41 and ADE15, a dominant adenine auxotroph. Mol Gen Genet 123(3):199-208
Woods RA and Jackson IE  (1973) The accumulation of glycinamide ribotide by ade3 and ade8 mutants of Saccharomyces cerevisiae. Biochem Biophys Res Commun 53(3):787-93
Jones EW  (1972) Fine Structure Analysis of the ade3 Locus in SACCHAROMYCES CEREVISIAE. Genetics 70(2):233-250
Jones EW  (1972) Nonsense mutations in the ade3 locus of Saccharomyces cerevisiae. Genetics 71(2):217-32
Lomax CA, et al.  (1971) New mutant types at the ade3 locus of Saccharomyces cerevisiae. J Bacteriol 107(1):1-7
ROMAN H  (1956) Studies of gene mutation in Saccharomyces. Cold Spring Harb Symp Quant Biol 21():175-85