COX2/Q0250 Literature Guide Help

Other names published for COX2: OXI1, OXII, cytochrome c oxidase subunit 2, Q0250

COX2 - Mutants/Phenotypes (49)

ReferenceOther Genes Addressed
Cruz-Torres V, et al.  (2012) The cytosol-synthesized subunit II (Cox2) precursor with the point mutation W56R is correctly processed in yeast mitochondria to rescue cytochrome oxidase. Biochim Biophys Acta 1817(12):2128-39
Elliott LE, et al.  (2012) Multiple roles of the Cox20 chaperone in assembly of Saccharomyces cerevisiae cytochrome c oxidase. Genetics 190(2):559-67
Mick DU, et al.  (2010) Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria. J Cell Biol 191(1):141-54
Shingu-Vazquez M, et al.  (2010) The carboxyl-terminal end of Cox1 is required for feedback assembly regulation of Cox1 synthesis in Saccharomyces cerevisiae mitochondria. J Biol Chem 285(45):34382-9
Supekova L, et al.  (2010) A single mutation in the first transmembrane domain of yeast COX2 enables its allotopic expression. Proc Natl Acad Sci U S A 107(11):5047-52
Perez-Martinez X, et al.  (2009) Dual Functions of Mss51 Couple Synthesis of Cox1 to Assembly of Cytochrome c Oxidase in Saccharomyces cerevisiae Mitochondria. Mol Biol Cell 20(20):4371-80
Herst PM, et al.  (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Fiumera HL, et al.  (2007) Translocation of mitochondrially synthesized Cox2 domains from the matrix to the intermembrane space. Mol Cell Biol 27(13):4664-73
Khalimonchuk O, et al.  (2007) Evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase. J Biol Chem 282(24):17442-9
Cobine PA, et al.  (2006) Mitochondrial matrix copper complex used in metallation of cytochrome oxidase and superoxide dismutase. J Biol Chem 281(48):36552-9
Polevoda B, et al.  (2006) The yeast translation release factors Mrf1p and Sup45p (eRF1) are methylated, respectively, by the methyltransferases Mtq1p and Mtq2p. J Biol Chem 281(5):2562-71
Williams EH, et al.  (2005) Alteration of a novel dispensable mitochondrial ribosomal small-subunit protein, Rsm28p, allows translation of defective COX2 mRNAs. Eukaryot Cell 4(2):337-45
Xu N, et al.  (2005) Mitochondrial DNA impacts the morphology of mitochondrial compartments. Gene 354:37-42
Herrmann JM and Bonnefoy N  (2004) Protein export across the inner membrane of mitochondria: the nature of translocated domains determines the dependence on the Oxa1 translocase. J Biol Chem 279(4):2507-12
Bonnefoy N, et al.  (2001) Mitochondrial translation of Saccharomyces cerevisiae COX2 mRNA is controlled by the nucleotide sequence specifying the pre-Cox2p leader peptide. Mol Cell Biol 21(7):2359-72
Dagsgaard C, et al.  (2001) Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast: evidence for a signaling pathway from the mitochondrial genome to the nucleus. J Biol Chem 276(10):7593-601
Machingo Q, et al.  (2001) Second-site, intragenic alterations in the gene encoding subunit II of cytochrome c oxidase from yeast can suppress two different missense mutations. Curr Genet 39(5-6):297-304
Kolesnikova OA, et al.  (2000) Suppression of mutations in mitochondrial DNA by tRNAs imported from the cytoplasm. Science 289(5486):1931-3
Mazourek M, et al.  (1999) Analysis of strains of Saccharomyces cerevisiae with amino acid substitutions in the Cu(A)-binding region of subunit II of cytochrome c oxidase. Curr Genet 36(5):249-55
Green-Willms NS, et al.  (1998) Functional interactions between yeast mitochondrial ribosomes and mRNA 5' untranslated leaders. Mol Cell Biol 18(4):1826-34
Dunstan HM, et al.  (1997) In vivo analysis of Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader functions in mitochondrial translation initiation and translational activation. Genetics 147(1):87-100
He S and Fox TD  (1997) Membrane translocation of mitochondrially coded Cox2p: distinct requirements for export of N and C termini and dependence on the conserved protein Oxa1p. Mol Biol Cell 8(8):1449-60
Meyer W, et al.  (1997) A mutation in cytochrome oxidase subunit 2 restores respiration of the mutant pet ts1402. Curr Genet 31(5):401-7
Torello AT, et al.  (1997) Deletion of the leader peptide of the mitochondrially encoded precursor of Saccharomyces cerevisiae cytochrome c oxidase subunit II. Genetics 145(4):903-10
Wiesenberger G and Fox TD  (1997) Pet127p, a membrane-associated protein involved in stability and processing of Saccharomyces cerevisiae mitochondrial RNAs. Mol Cell Biol 17(5):2816-24
Overholtzer MH, et al.  (1996) The effect of amino acid substitutions in the conserved aromatic region of subunit II of cytochrome c oxidase in Saccharomyces cerevisiae. J Biol Chem 271(13):7719-24
Meunier B, et al.  (1995) The topology of CuA in relation to the other metal centres in cytochrome-c oxidase of Saccharomyces cerevisiae as determined by analysis of second-site reversions. Biochim Biophys Acta 1253(1):13-5
Speno H, et al.  (1995) Identification of essential amino acids within the proposed CuA binding site in subunit II of Cytochrome c oxidase. J Biol Chem 270(43):25363-9
Mulero JJ and Fox TD  (1994) Reduced but accurate translation from a mutant AUA initiation codon in the mitochondrial COX2 mRNA of Saccharomyces cerevisiae. Mol Gen Genet 242(4):383-90
Meunier B, et al.  (1993) Genetic screening in Saccharomyces cerevisiae for large numbers of mitochondrial point mutations which affect structure and function of catalytic subunits of cytochrome-c oxidase. Eur J Biochem 213(1):129-35