TLC1 Literature Guide Help

Other names published for TLC1: TER1

TLC1 - Mutants/Phenotypes (113)

ReferenceOther Genes Addressed
Lebo KJ and Zappulla DC  (2012) Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo. RNA 18(9):1666-78
Lubin JW, et al.  (2012) The interaction between the yeast telomerase RNA and the Est1 protein requires three structural elements. RNA 18(9):1597-604
Luciano P, et al.  (2012) RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts. EMBO J 31(8):2034-46
Noel JF, et al.  (2012) Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway. Nucleic Acids Res 40(12):5625-36
Paschini M, et al.  (2012) A naturally thermolabile activity compromises genetic analysis of telomere function in Saccharomyces cerevisiae. Genetics 191(1):79-93
Peng J and Zhou JQ  (2012) The tail-module of yeast Mediator complex is required for telomere heterochromatin maintenance. Nucleic Acids Res 40(2):581-93
Ribaud V, et al.  (2012) DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1. EMBO J 31(1):138-49
Bah A, et al.  (2011) Telomerase is required to protect chromosomes with vertebrate-type T2AG3 3' ends in Saccharomyces cerevisiae. J Biol Chem 286(31):27132-8
Bairley RC, et al.  (2011) A mutation in the catalytic subunit of yeast telomerase alters primer-template alignment while promoting processivity and protein-DNA binding. J Cell Sci 124(Pt 24):4241-52
Deshpande AM, et al.  (2011) Polymerase epsilon is required to maintain replicative senescence. Mol Cell Biol 31(8):1637-45
Gallardo F, et al.  (2011) Live cell imaging of telomerase RNA dynamics reveals cell cycle-dependent clustering of telomerase at elongating telomeres. Mol Cell 44(5):819-27
Kwan EX, et al.  (2011) Natural Polymorphism in BUL2 Links Cellular Amino Acid Availability with Chronological Aging and Telomere Maintenance in Yeast. PLoS Genet 7(8):e1002250
Noel JF and Wellinger RJ  (2011) Abrupt telomere losses and reduced end-resection can explain accelerated senescence of Smc5/6 mutants lacking telomerase. DNA Repair (Amst) 10(3):271-82
Smith JS, et al.  (2011) Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nat Struct Mol Biol 18(4):478-85
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Tuzon CT, et al.  (2011) The Saccharomyces cerevisiae Telomerase Subunit Est3 Binds Telomeres in a Cell Cycle- and Est1-Dependent Manner and Interacts Directly with Est1 In Vitro. PLoS Genet 7(5):e1002060
Zappulla DC, et al.  (2011) Ku can contribute to telomere lengthening in yeast at multiple positions in the telomerase RNP. RNA 17(2):298-311
Chavez A, et al.  (2010) Sumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution. J Biol Chem 285(16):11922-30
Dewar JM and Lydall D  (2010) Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. EMBO J 29(23):4020-34
Gao H, et al.  (2010) Telomerase Recruitment in Saccharomyces cerevisiae Is Not Dependent on Tel1-Mediated Phosphorylation of Cdc13. Genetics 186(4):1147-59
Joseph IS, et al.  (2010) An mre11 Mutation That Promotes Telomere Recombination and an Efficient Bypass of Senescence. Genetics 185(3):761-70
Kozak ML, et al.  (2010) Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J 29(1):158-70
Lee J, et al.  (2010) Investigating the role of the Est3 protein in yeast telomere replication. Nucleic Acids Res 38(7):2279-90
Lu CY, et al.  (2010) Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast. Nucleic Acids Res 38(2):488-98
Matsui A and Matsuura A  (2010) Cell size regulation during telomere-directed senescence in Saccharomyces cerevisiae. Biosci Biotechnol Biochem 74(1):195-8
McGee JS, et al.  (2010) Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair. Nat Struct Mol Biol 17(12):1438-45
Meng FL, et al.  (2010) Sua5p is required for telomere recombination in Saccharomyces cerevisiae. Cell Res 20(4):495-8
Vodenicharov MD, et al.  (2010) Telomere capping in non-dividing yeast cells requires Yku and Rap1. EMBO J 29(17):3007-19
Abdallah P, et al.  (2009) A two-step model for senescence triggered by a single critically short telomere. Nat Cell Biol 11(8):988-93
Enserink JM, et al.  (2009) Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol 185(3):423-37