MCM4/YPR019W Literature Guide Help

Other names published for MCM4: HCD21, CDC54, YPR019W

MCM4 - Mutants/Phenotypes (32)

Results: 1 - 30 of 32 records
   1  2 
ReferenceOther Genes Addressed
Cheng E, et al.  (2012) Genome rearrangements caused by depletion of essential DNA replication proteins in Saccharomyces cerevisiae. Genetics 192(1):147-60
Zhang Y, et al.  (2012) Genome-wide screen identifies pathways that govern GAA/TTC repeat fragility and expansions in dividing and nondividing yeast cells. Mol Cell 48(2):254-65
Li XC and Tye BK  (2011) Ploidy Dictates Repair Pathway Choice under DNA Replication Stress. Genetics 187(4):1031-40
Bochman ML and Schwacha A  (2010) The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'. Nucleic Acids Res 38(18):6078-88
Lydeard JR, et al.  (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev 24(11):1133-44
Ma L, et al.  (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410
Ma X, et al.  (2010) The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 function. BMC Biochem 11():37
Randell JC, et al.  (2010) Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7. Mol Cell 40(3):353-63
Sheu YJ and Stillman B  (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463(7277):113-7
Li XC, et al.  (2009) Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS Biol 7(7):e1000161
Nishimura K, et al.  (2009) An auxin-based degron system for the rapid depletion of proteins in nonplant cells. Nat Methods 6(12):917-22
Stead BE, et al.  (2009) ATP binding and hydrolysis by Mcm2 regulate DNA binding by Mcm complexes. J Mol Biol 391(2):301-13
Steere NA, et al.  (2009) Functional screen of human MCM2-7 variant alleles for disease-causing potential. Mutat Res 666(1-2):74-8
Bochman ML, et al.  (2008) Subunit organization of Mcm2-7 and the unequal role of active sites in ATP hydrolysis and viability. Mol Cell Biol 28(19):5865-73
Devault A, et al.  (2008) Interplay between S-Cyclin-dependent Kinase and Dbf4-dependent Kinase in Controlling DNA Replication through Phosphorylation of Yeast Mcm4 N-Terminal Domain. Mol Biol Cell 19(5):2267-77
Bochman ML and Schwacha A  (2007) Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step. J Biol Chem 282(46):33795-804
Hoang ML, et al.  (2007) Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Mol Cell Biol 27(21):7594-602
Shima N, et al.  (2007) A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat Genet 39(1):93-8
Kanemaki M and Labib K  (2006) Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks. EMBO J 25(8):1753-63
Sheu YJ and Stillman B  (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell 24(1):101-13
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Ricke RM and Bielinsky AK  (2004) Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. Mol Cell 16(2):173-85
Nguyen VQ, et al.  (2001) Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. Nature 411(6841):1068-73
Schwacha A and Bell SP  (2001) Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication. Mol Cell 8(5):1093-104
Labib K, et al.  (2000) Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 288(5471):1643-7
Tye BK and Sawyer S  (2000) The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts. J Biol Chem 275(45):34833-6
Tye BK  (1999) Minichromosome maintenance as a genetic assay for defects in DNA replication. Methods 18(3):329-34
Loo S, et al.  (1995) The origin recognition complex in silencing, cell cycle progression, and DNA replication. Mol Biol Cell 6(6):741-56
Chen Y, et al.  (1992) CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences. Proc Natl Acad Sci U S A 89(21):10459-63
Results: 1 - 30 of 32 records
   1  2