KES1/YPL145C Literature Guide Help

Other names published for KES1: LPI3, OSH4, BSR3, YPL145C

KES1 - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Tsujimoto Y, et al.  (2013) Functional roles of YPT31 and YPT32 in clotrimazole resistance of Saccharomyces cerevisiae through effects on vacuoles and ATP-binding cassette transporter(s). J Biosci Bioeng 115(1):4-11
Mousley CJ, et al.  (2012) A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing. Cell 148(4):702-15
Rogaski B and Klauda JB  (2012) Membrane-binding mechanism of a peripheral membrane protein through microsecond molecular dynamics simulations. J Mol Biol 423(5):847-61
Alfaro G, et al.  (2011) The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis. Traffic 12(11):1521-36
Ambroset C, et al.  (2011) Deciphering the molecular basis of wine yeast fermentation traits using a combined genetic and genomic approach. G3 (Bethesda) 1(4):263-81
Georgiev A, et al.  (2011) Osh proteins regulate membrane sterol organization but are not required for sterol movement between the ER and PM. Traffic 12(10):1341-55
Soper JH, et al.  (2011) Aggregation of alpha-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis. J Mol Neurosci 43(3):391-405
Stefan CJ, et al.  (2011) Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites. Cell 144(3):389-401
de Saint-Jean M, et al.  (2011) Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol 195(6):965-78
LeBlanc MA and McMaster CR  (2010) Lipid binding requirements for oxysterol-binding protein Kes1 inhibition of autophagy and endosome-trans-Golgi trafficking pathways. J Biol Chem 285(44):33875-84
Muthusamy BP, et al.  (2009) Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Mol Biol Cell 20(12):2920-31
Schulz TA, et al.  (2009) Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues. J Cell Biol 187(6):889-903
Mousley CJ, et al.  (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803
Drin G, et al.  (2007) A general amphipathic alpha-helical motif for sensing membrane curvature. Nat Struct Mol Biol 14(2):138-46
Fairn GD, et al.  (2007) The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function. Proc Natl Acad Sci U S A 104(39):15352-7
Howe AG, et al.  (2007) Regulation of Phosphoinositide Levels by the Phospholipid Transfer Protein Sec14p Controls Cdc42p/p21-Activated Kinase-Mediated Cell Cycle Progression at Cytokinesis. Eukaryot Cell 6(10):1814-23
Raychaudhuri S, et al.  (2006) Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J Cell Biol 173(1):107-19
Sullivan DP, et al.  (2006) Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast. Biochem Soc Trans 34(Pt 3):356-8
Fairn GD and McMaster CR  (2005) Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related protein 1 short) in the regulation of vesicular transport. Biochem J 387(Pt 3):889-96
Fairn GD and McMaster CR  (2005) The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport. Biochem Cell Biol 83(5):631-6
Proszynski TJ, et al.  (2005) A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci U S A 102(50):17981-6
Sano T, et al.  (2005) Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants. J Biol Chem 280(44):36674-82
Beh CT and Rine J  (2004) A role for yeast oxysterol-binding protein homologs in endocytosis and in the maintenance of intracellular sterol-lipid distribution. J Cell Sci 117(Pt 14):2983-96
Coluccio A, et al.  (2004) Genetic evidence of a role for membrane lipid composition in the regulation of soluble NEM-sensitive factor receptor function in Saccharomyces cerevisiae. Genetics 166(1):89-97
Kvam E and Goldfarb DS  (2004) Nvj1p is the outer-nuclear-membrane receptor for oxysterol-binding protein homolog Osh1p in Saccharomyces cerevisiae. J Cell Sci 117(Pt 21):4959-68
Li X, et al.  (2002) Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol 157(1):63-77
Beh CT, et al.  (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40
Stevenson LF, et al.  (2001) A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Proc Natl Acad Sci U S A 98(7):3946-51
Xu Y, et al.  (2001) Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport. J Biol Chem 276(21):18407-14
Jiang B, et al.  (1994) A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein. Yeast 10(3):341-53