ALD6/YPL061W Literature Guide Help

Other names published for ALD6: ALD1, aldehyde dehydrogenase (NADP(+)) ALD6, YPL061W

ALD6 - Mutants/Phenotypes (29)

ReferenceOther Genes Addressed
Ayer A, et al.  (2012) A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis. PLoS One 7(9):e44278
Jain VK, et al.  (2012) Effect of alternative NAD+-regenerating pathways on the formation of primary and secondary aroma compounds in a Saccharomyces cerevisiae glycerol-defective mutant. Appl Microbiol Biotechnol 93(1):131-41
Lee SH, et al.  (2012) Effects of NADH-preferring xylose reductase expression on ethanol production from xylose in xylose-metabolizing recombinant Saccharomyces cerevisiae. J Biotechnol 158(4):184-91
Nakahara K, et al.  (2012) The sjogren-larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell 46(4):461-71
Ng CY, et al.  (2012) Production of 2,3-butanediol in Saccharomyces cerevisiae by in silico aided metabolic engineering. Microb Cell Fact 11(1):68
Varela C, et al.  (2012) Evaluation of gene modification strategies for the development of low-alcohol-wine yeasts. Appl Environ Microbiol 78(17):6068-77
Zheng DQ, et al.  (2012) Genome sequencing and genetic breeding of a bioethanol Saccharomyces cerevisiae strain YJS329. BMC Genomics 13(1):479
Dziedzic SA and Caplan AB  (2011) Identification of autophagy genes participating in zinc-induced necrotic cell death in Saccharomyces cerevisiae. Autophagy 7(5):490-500
Hector RE, et al.  (2011) Saccharomyces cerevisiae engineered for xylose metabolism requires gluconeogenesis and the oxidative branch of the pentose phosphate pathway for aerobic xylose assimilation. Yeast 28(9):645-60
Park SE, et al.  (2011) Expression of aldehyde dehydrogenase 6 reduces inhibitory effect of furan derivatives on cell growth and ethanol production in Saccharomyces cerevisiae. Bioresour Technol 102(10):6033-6038
Ehsani M, et al.  (2009) Engineering of 2,3-butanediol dehydrogenase to reduce acetoin formation by glycerol-overproducing, low-alcohol Saccharomyces cerevisiae. Appl Environ Microbiol 75(10):3196-205
Yoshikawa K, et al.  (2009) Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae. FEMS Yeast Res 9(1):32-44
Herrero AB, et al.  (2008) Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734. Cancer Res 68(23):9779-87
Matsufuji Y, et al.  (2008) Acetaldehyde tolerance in Saccharomyces cerevisiae involves the pentose phosphate pathway and oleic acid biosynthesis. Yeast 25(11):825-33
Ng CH, et al.  (2008) Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: The role of NADPH-generating systems and the SKN7 transcription factor. Free Radic Biol Med 44(6):1131-45
Doostzadeh J, et al.  (2007) Chemical genomic profiling for identifying intracellular targets of toxicants producing Parkinson's disease. Toxicol Sci 95(1):182-7
Cambon B, et al.  (2006) Effects of GPD1 Overexpression in Saccharomyces cerevisiae Commercial Wine Yeast Strains Lacking ALD6 Genes. Appl Environ Microbiol 72(7):4688-94
Blank LM, et al.  (2005) Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast. Genome Biol 6(6):R49
Minard KI and McAlister-Henn L  (2005) Sources of NADPH in yeast vary with carbon source. J Biol Chem 280(48):39890-6
Butcher RA and Schreiber SL  (2004) Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection. Proc Natl Acad Sci U S A 101(21):7868-73
Saint-Prix F, et al.  (2004) Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation. Microbiology 150(Pt 7):2209-20
Sonderegger M, et al.  (2004) Metabolic engineering of a phosphoketolase pathway for pentose catabolism in Saccharomyces cerevisiae. Appl Environ Microbiol 70(5):2892-7
Grabowska D and Chelstowska A  (2003) The ALD6 gene product is indispensable for providing NADPH in yeast cells lacking glucose-6-phosphate dehydrogenase activity. J Biol Chem 278(16):13984-8
Eglinton JM, et al.  (2002) Decreasing acetic acid accumulation by a glycerol overproducing strain of Saccharomyces cerevisiae by deleting the ALD6 aldehyde dehydrogenase gene. Yeast 19(4):295-301
Rosenfeld E, et al.  (2002) Non-respiratory oxygen consumption pathways in anaerobically-grown Saccharomyces cerevisiae: evidence and partial characterization. Yeast 19(15):1299-321
Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
Remize F, et al.  (2000) Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae: role of the cytosolic Mg(2+) and mitochondrial K(+) acetaldehyde dehydrogenases Ald6p and Ald4p in acetate formation during alcoholic fermentation. Appl Environ Microbiol 66(8):3151-9
Wang X, et al.  (1998) Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae. J Bacteriol 180(4):822-30
Meaden PG, et al.  (1997) The ALD6 gene of Saccharomyces cerevisiae encodes a cytosolic, Mg(2+)-activated acetaldehyde dehydrogenase. Yeast 13(14):1319-27