HST2/YPL015C Literature Guide Help

Other names published for HST2: YPL015C

HST2 - Mutants/Phenotypes (27)

ReferenceOther Genes Addressed
Bheda P, et al.  (2012) Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2. Proc Natl Acad Sci U S A 109(16):E916-25
Cesarini E, et al.  (2012) H4K16 acetylation affects recombination and ncRNA transcription at rDNA in Saccharomyces cerevisiae. Mol Biol Cell 23(14):2770-81
Orozco H, et al.  (2012) Wine yeast sirtuins and Gcn5p control aging and metabolism in a natural growth medium. Mech Ageing Dev 133(5):348-358
Tripathi K, et al.  (2012) Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. FEMS Yeast Res 12(8):949-57
Beckouet F, et al.  (2010) An smc3 acetylation cycle is essential for establishment of sister chromatid cohesion. Mol Cell 39(5):689-99
Dietvorst J and Brandt A  (2010) Histone modifying proteins Gcn5 and Hda1 affect flocculation in Saccharomyces cerevisiae during high-gravity fermentation. Curr Genet 56(1):75-85
Liu B, et al.  (2010) The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates. Cell 140(2):257-267
Xiong B, et al.  (2010) Hos1 is a lysine deacetylase for the smc3 subunit of cohesin. Curr Biol 20(18):1660-5
Eisenberg T, et al.  (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11(11):1305-14
Easlon E, et al.  (2008) The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast. Genes Dev 22(7):931-44
Lee S, et al.  (2008) Quantification of endogenous sirtuin metabolite O-acetyl-ADP-ribose. Anal Biochem 383(2):174-9
Murakami CJ, et al.  (2008) A method for high-throughput quantitative analysis of yeast chronological life span. J Gerontol A Biol Sci Med Sci 63(2):113-21
Wang CL, et al.  (2008) A yeast sir2 mutant temperature sensitive for silencing. Genetics 180(4):1955-62
Easlon E, et al.  (2007) The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension. J Biol Chem 282(9):6161-71
Medvedik O, et al.  (2007) MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 5(10):e261
Smith DL Jr, et al.  (2007) Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Aging Cell 6(5):649-62
Kaeberlein M, et al.  (2006) Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312(5778):1312; author reply 1312
Khan AN and Lewis PN  (2006) Use of substrate analogs and mutagenesis to study substrate binding and catalysis in the Sir2 family of NAD-dependent protein deacetylases. J Biol Chem 281(17):11702-11
Tsuchiya M, et al.  (2006) Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast. Aging Cell 5(6):505-14
Vaquero A, et al.  (2006) SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 20(10):1256-61
Wilson JM, et al.  (2006) Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. EMBO Rep 7(12):1247-51
Lamming DW, et al.  (2005) HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309(5742):1861-4
Bedalov A, et al.  (2003) NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae. Mol Cell Biol 23(19):7044-54
Starai VJ, et al.  (2003) Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae. Genetics 163(2):545-55
Bedalov A, et al.  (2001) Identification of a small molecule inhibitor of Sir2p. Proc Natl Acad Sci U S A 98(26):15113-8
Perrod S, et al.  (2001) A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J 20(1-2):197-209
Smith JS, et al.  (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97(12):6658-63