GSH2/YOL049W Literature Guide Help

Other names published for GSH2: glutathione synthase, YOL049W

GSH2 - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Matsufuji Y, et al.  (2013) Novel physiological roles for glutathione in sequestering acetaldehyde to confer acetaldehyde tolerance in Saccharomyces cerevisiae. Appl Microbiol Biotechnol 97(1):297-303
Kiriyama K, et al.  (2012) Extracellular glutathione fermentation using engineered Saccharomyces cerevisiae expressing a novel glutathione exporter. Appl Microbiol Biotechnol 96(4):1021-7
Lis P, et al.  (2012) Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr 44(1):155-61
Yoon HS, et al.  (2012) Glutathione reductase from Brassica rapa affects tolerance and the redox state but not fermentation ability in response to oxidative stress in genetically modified Saccharomyces cerevisiae. World J Microbiol Biotechnol 28(5):1901-15
Reeder NL, et al.  (2011) Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins. Antimicrob Agents Chemother 55(12):5753-60
Suzuki T, et al.  (2011) Identification and characterization of genes involved in glutathione production in yeast. J Biosci Bioeng 112(2):107-13
Yoshida H, et al.  (2011) Enzymatic glutathione production using metabolically engineered Saccharomyces cerevisiae as a whole-cell biocatalyst. Appl Microbiol Biotechnol 91(4):1001-6
Zechmann B, et al.  (2011) Subcellular distribution of glutathione and its dynamic changes under oxidative stress in the yeast Saccharomyces cerevisiae. FEMS Yeast Res 11(8):631-42
Ayer A, et al.  (2010) The critical role of glutathione in maintenance of the mitochondrial genome. Free Radic Biol Med 49(12):1956-68
Bitew T, et al.  (2010) Vitamin E Prevents Lipid Raft Modifications Induced by an Anti-cancer Lysophospholipid and Abolishes a Yap1-mediated Stress Response in Yeast. J Biol Chem 285(33):25731-42
Delalande O, et al.  (2010) Cadmium-glutathione solution structures provide new insights into heavy metal detoxification. FEBS J 277(24):5086-96
Kim Y, et al.  (2010) Redox regulation of the tumor suppressor PTEN by glutathione. FEBS Lett 584(16):3550-3556
Ottosson LG, et al.  (2010) Sulfate Assimilation Mediates Tellurite Reduction and Toxicity in Saccharomyces cerevisiae. Eukaryot Cell 9(10):1635-1647
Deffieu M, et al.  (2009) Glutathione participates in the regulation of mitophagy in yeast. J Biol Chem 284(22):14828-37
Gales G, et al.  (2008) Role of glutathione metabolism status in the definition of some cellular parameters and oxidative stress tolerance of Saccharomyces cerevisiae cells growing as biofilms. FEMS Yeast Res 8(5):667-75
Kumanovics A, et al.  (2008) Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis. J Biol Chem 283(16):10276-86
Serero A, et al.  (2008) Yeast genes involved in cadmium tolerance: Identification of DNA replication as a target of cadmium toxicity. DNA Repair (Amst) 7(8):1262-75
Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
Preveral S, et al.  (2006) Metal(loid)s and radionuclides cytotoxicity in Saccharomyces cerevisiae. Role of YCF1, glutathione and effect of buthionine sulfoximine. Biochimie 88(11):1651-63
Basu U, et al.  (2004) Reverse genetic analysis of the glutathione metabolic pathway suggests a novel role of PHGPX and URE2 genes in aluminum resistance in Saccharomyces cerevisiae. Mol Genet Genomics 271(5):627-37
Willingham S, et al.  (2003) Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. Science 302(5651):1769-72
Trotter EW and Grant CM  (2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae. Mol Microbiol 46(3):869-78
Wheeler GL, et al.  (2002) Glutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor. Mol Microbiol 46(2):545-56
Sugiyama K, et al.  (2000) Role of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae. Biochem J 352 Pt 1():71-8
Evans MV, et al.  (1998) Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: involvement of a respiration-related process for maximal sensitivity and adaptive response. J Bacteriol 180(3):483-90
Inoue Y, et al.  (1998) Molecular identification of glutathione synthetase (GSH2) gene from Saccharomyces cerevisiae. Biochim Biophys Acta 1395(3):315-20
Chaudhuri B, et al.  (1997) apd1+, a gene required for red pigment formation in ade6 mutants of Schizosaccharomyces pombe, encodes an enzyme required for glutathione biosynthesis: a role for glutathione and a glutathione-conjugate pump. Genetics 145(1):75-83
Grant CM, et al.  (1997) Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine. Mol Biol Cell 8(9):1699-707
Inoue Y and Kimura A  (1996) Identification of the structural gene for glyoxalase I from Saccharomyces cerevisiae. J Biol Chem 271(42):25958-65
OhtakeY, et al.  (1990) Isolation and characterization of glutathione biosynthesis-deficient mutants in Saccharomyces cerevisiae. Agric Biol Chem 54:3145-3150