FPR1/YNL135C Literature Guide Help

Other names published for FPR1: FKB1, RBP1, peptidylprolyl isomerase FPR1, YNL135C

FPR1 - Mutants/Phenotypes (51)

ReferenceOther Genes Addressed
Hemenway CS, et al.  (1995) vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. Genetics 141(3):833-44
Lorenz MC and Heitman J  (1995) TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J Biol Chem 270(46):27531-7
Benton BM, et al.  (1994) A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol 127(3):623-39
Bossard MJ, et al.  (1994) Catalytic and ligand binding properties of the FK506 binding protein FKBP12: effects of the single amino acid substitution of Tyr82 to Leu. Biochem J 297 ( Pt 2)():365-72
Breuder T, et al.  (1994) Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. Proc Natl Acad Sci U S A 91(12):5372-6
Cardenas ME, et al.  (1994) Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. EMBO J 13(24):5944-57
Manning-Krieg UC, et al.  (1994) Purification of FKBP-70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene, FPR3. FEBS Lett 352(1):98-103
Cafferkey R, et al.  (1993) Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity. Mol Cell Biol 13(10):6012-23
Heitman J, et al.  (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9
Koser PL, et al.  (1993) The tyrosine89 residue of yeast FKBP12 is required for rapamycin binding. Gene 129(2):159-65
Parent SA, et al.  (1993) Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae. J Gen Microbiol 139(12):2973-84
Sykes K, et al.  (1993) Proline isomerases function during heat shock. Proc Natl Acad Sci U S A 90(12):5853-7
Davis ES, et al.  (1992) A yeast cyclophilin gene essential for lactate metabolism at high temperature. Proc Natl Acad Sci U S A 89(23):11169-73
McLaughlin MM, et al.  (1992) The yeast cyclophilin multigene family: purification, cloning and characterization of a new isoform. Gene 111(1):85-92
Nielsen JB, et al.  (1992) Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2. Proc Natl Acad Sci U S A 89(16):7471-5
Brizuela L, et al.  (1991) Antifungal properties of the immunosuppressant FK-506: identification of an FK-506-responsive yeast gene distinct from FKB1. Mol Cell Biol 11(9):4616-26
Heitman J, et al.  (1991) FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88(5):1948-52
Heitman J, et al.  (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253(5022):905-9
Koltin Y, et al.  (1991) Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein. Mol Cell Biol 11(3):1718-23
Koser PL, et al.  (1991) The CYP2 gene of Saccharomyces cerevisiae encodes a cyclosporin A-sensitive peptidyl-prolyl cis-trans isomerase with an N-terminal signal sequence. Gene 108(1):73-80
Wiederrecht G, et al.  (1991) FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins. Proc Natl Acad Sci U S A 88(3):1029-33