TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Mutants/Phenotypes (91)

Results: 1 - 30 of 91 records
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ReferenceOther Genes Addressed
Bock LJ, et al.  (2012) Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore. Nat Cell Biol 14(6):614-24
Garcia-Rubio ML and Aguilera A  (2012) Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes. Nucleic Acids Res 40(3):1050-64
Hashash N, et al.  (2012) Topoisomerase II- and Condensin-Dependent Breakage of MEC1(ATR)-Sensitive Fragile Sites Occurs Independently of Spindle Tension, Anaphase, or Cytokinesis. PLoS Genet 8(10):e1002978
Joshi RS, et al.  (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15
Schmidt BH, et al.  (2012) Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat Struct Mol Biol 19(11):1147-54
Baxter J, et al.  (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science 331(6022):1328-32
French SL, et al.  (2011) Distinguishing the Roles of Topoisomerases I and II in Relief of Transcription-Induced Torsional Stress in Yeast rRNA Genes. Mol Cell Biol 31(3):482-94
Kegel A, et al.  (2011) Chromosome length influences replication-induced topological stress. Nature 471(7338):392-6
Martins-Taylor K, et al.  (2011) H2A.Z (Htz1) Controls the Cell-Cycle-Dependent Establishment of Transcriptional Silencing at Saccharomyces cerevisiae Telomeres. Genetics 187(1):89-104
Sperling AS, et al.  (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proc Natl Acad Sci U S A 108(31):12693-8
Bermudez I, et al.  (2010) A method for genome-wide analysis of DNA helical tension by means of psoralen-DNA photobinding. Nucleic Acids Res 38(19):e182
El Hage A, et al.  (2010) Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev 24(14):1546-58
Fachinetti D, et al.  (2010) Replication Termination at Eukaryotic Chromosomes Is Mediated by Top2 and Occurs at Genomic Loci Containing Pausing Elements. Mol Cell 39(4):595-605
Joshi RS, et al.  (2010) Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes. EMBO J 29(4):740-8
Renshaw MJ, et al.  (2010) Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation. Dev Cell 19(2):232-244
Bermejo R, et al.  (2009) Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription. Cell 138(5):870-84
Furniss K, et al.  (2009) Assaying Topoisomerase II Checkpoints in Yeast. Methods Mol Biol 582:167-87
Mendoza M, et al.  (2009) A mechanism for chromosome segregation sensing by the NoCut checkpoint. Nat Cell Biol 11(4):477-83
Roca J  (2009) Two-dimensional agarose gel electrophoresis of DNA topoisomers. Methods Mol Biol 582():27-37
Baxter J and Diffley JF  (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell 30(6):790-802
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
D'Ambrosio C, et al.  (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9
Meczes EL, et al.  (2008) The impact of the human DNA topoisomerase II C-terminal domain on activity. PLoS ONE 3(3):e1754
Rogojina AT and Nitiss JL  (2008) Isolation and Characterization of mAMSA-hypersensitive Mutants: CYTOTOXICITY OF Top2 COVALENT COMPLEXES CONTAINING DNA SINGLE STRAND BREAKS. J Biol Chem 283(43):29239-50
Takahashi Y and Strunnikov A  (2008) In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma 117(2):189-98
Takahashi Y, et al.  (2008) Cooperation of sumoylated chromosomal proteins in rDNA maintenance. PLoS Genet 4(10):e1000215
Warsi TH, et al.  (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33
Ivanov D and Nasmyth K  (2007) A physical assay for sister chromatid cohesion in vitro. Mol Cell 27(2):300-10
Andrews CA, et al.  (2006) A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. Genes Dev 20(9):1162-74
Cline SD and Hanawalt PC  (2006) Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae. DNA Repair (Amst) 5(5):611-7
Results: 1 - 30 of 91 records
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