YKU80/YMR106C Literature Guide Help

Other names published for YKU80: HDF2, YMR106C

YKU80 - Mutants/Phenotypes (108)

ReferenceOther Genes Addressed
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
LeBel C, et al.  (2006) Assessing telomeric phenotypes. Methods Mol Biol 313():265-316
Malik M, et al.  (2006) Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage. Mol Cancer Ther 5(6):1405-14
Nitiss KC, et al.  (2006) Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage. Proc Natl Acad Sci U S A 103(24):8953-8
Corda Y, et al.  (2005) Inactivation of Ku-mediated end joining suppresses mec1Delta lethality by depleting the ribonucleotide reductase inhibitor Sml1 through a pathway controlled by Tel1 kinase and the Mre11 complex. Mol Cell Biol 25(23):10652-64
Palmbos PL, et al.  (2005) Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining. Mol Cell Biol 25(24):10782-90
Pardo B and Marcand S  (2005) Rap1 prevents telomere fusions by nonhomologous end joining. EMBO J 24(17):3117-27
Ruan C, et al.  (2005) The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching. Mol Cell Biol 25(19):8476-85
Taddei A, et al.  (2005) Multiple pathways tether telomeres and silent chromatin at the nuclear periphery: functional implications for sir-mediated repression. Novartis Found Symp 264:140-56; discussion 156-65, 227-30
Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63
Begley TJ, et al.  (2004) Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. Mol Cell 16(1):117-25
Bertuch AA and Lundblad V  (2004) EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae. Genetics 166(4):1651-9
Fisher TS, et al.  (2004) Cell cycle-dependent regulation of yeast telomerase by Ku. Nat Struct Mol Biol 11(12):1198-205
Roy R, et al.  (2004) Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J Biol Chem 279(1):86-94
Yu X and Gabriel A  (2004) Reciprocal translocations in Saccharomyces cerevisiae formed by nonhomologous end joining. Genetics 166(2):741-51
Bertuch AA and Lundblad V  (2003) The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini. Mol Cell Biol 23(22):8202-15
Leroy C, et al.  (2003) PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break. Mol Cell 11(3):827-35
Stellwagen AE, et al.  (2003) Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 17(19):2384-95
Yu X and Gabriel A  (2003) Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae. Genetics 163(3):843-56
Cosgrove AJ, et al.  (2002) Ku complex controls the replication time of DNA in telomere regions. Genes Dev 16(19):2485-90
DuBois ML, et al.  (2002) A quantitative assay for telomere protection in Saccharomyces cerevisiae. Genetics 161(3):995-1013
Frank-Vaillant M and Marcand S  (2002) Transient stability of DNA ends allows nonhomologous end joining to precede homologous recombination. Mol Cell 10(5):1189-99
Gravel S and Wellinger RJ  (2002) Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku. Mol Cell Biol 22(7):2182-93
Hediger F, et al.  (2002) Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr Biol 12(24):2076-89
Maringele L and Lydall D  (2002) EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants. Genes Dev 16(15):1919-33
Wilson TE  (2002) A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio. Genetics 162(2):677-88
Grenon M, et al.  (2001) Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. Nat Cell Biol 3(9):844-7
Maillet L, et al.  (2001) Ku-deficient yeast strains exhibit alternative states of silencing competence. EMBO Rep 2(3):203-10
Peterson SE, et al.  (2001) The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku. Nat Genet 27(1):64-7
Teo SH and Jackson SP  (2001) Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant. EMBO Rep 2(3):197-202