MEC3/YLR288C Literature Guide Help

Other names published for MEC3: PIP3, PSO9, YLR288C

MEC3 - Mutants/Phenotypes (59)

ReferenceOther Genes Addressed
Brendel M, et al.  (2003) Role of PSO genes in repair of DNA damage of Saccharomyces cerevisiae. Mutat Res 544(2-3):179-93
Giannattasio M, et al.  (2003) Correlation between checkpoint activation and in vivo assembly of the yeast checkpoint complex Rad17-Mec3-Ddc1. J Biol Chem 278(25):22303-8
King WR, et al.  (2003) Ionizing irradiation effects on S-phase in checkpoint mutants of the yeast Saccharomyces cerevisiae. Curr Genet 42(6):313-21
Mieczkowski PA, et al.  (2003) Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. Proc Natl Acad Sci U S A 100(19):10854-9
Birrell GW, et al.  (2002) Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc Natl Acad Sci U S A 99(13):8778-83
Chang M, et al.  (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci U S A 99(26):16934-9
Giannattasio M, et al.  (2002) A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1. Proc Natl Acad Sci U S A 99(20):12997-3002
Birrell GW, et al.  (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98(22):12608-13
Grandin N, et al.  (2001) Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J 20(21):6127-39
Klein HL  (2001) Mutations in recombinational repair and in checkpoint control genes suppress the lethal combination of srs2Delta with other DNA repair genes in Saccharomyces cerevisiae. Genetics 157(2):557-65
Melo JA, et al.  (2001) Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev 15(21):2809-21
Myung K, et al.  (2001) Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 104(3):397-408
Schramke V, et al.  (2001) The set1Delta mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes. Genes Dev 15(14):1845-58
Clarke DJ and Gimenez-Abian JF  (2000) Checkpoints controlling mitosis. Bioessays 22(4):351-63
Liberi G, et al.  (2000) Srs2 DNA helicase is involved in checkpoint response and its regulation requires a functional Mec1-dependent pathway and Cdk1 activity. EMBO J 19(18):5027-38
Basrai MA, et al.  (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9
Corda Y, et al.  (1999) Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions. Nat Genet 21(2):204-8
Grossmann KF, et al.  (1999) Cisplatin DNA cross-links do not inhibit S-phase and cause only a G2/M arrest in Saccharomyces cerevisiae. Mutat Res 434(1):29-39
Neecke H, et al.  (1999) Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast. EMBO J 18(16):4485-97
Thompson DA and Stahl FW  (1999) Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics 153(2):621-41
Boger-Nadjar E, et al.  (1998) Efficient initiation of S-phase in yeast requires Cdc40p, a protein involved in pre-mRNA splicing. Mol Gen Genet 260(2-3):232-41
de la Torre-Ruiz MA, et al.  (1998) RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activation. EMBO J 17(9):2687-98
Longhese MP, et al.  (1997) The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J 16(17):5216-26
Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
Marini F, et al.  (1997) A role for DNA primase in coupling DNA replication to DNA damage response. EMBO J 16(3):639-50
Brush GS, et al.  (1996) The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. Proc Natl Acad Sci U S A 93(26):15075-80
Longhese MP, et al.  (1996) Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase. Mol Cell Biol 16(7):3235-44
Weinert TA, et al.  (1994) Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8(6):652-65
Weinert TA  (1992) Dual cell cycle checkpoints sensitive to chromosome replication and DNA damage in the budding yeast Saccharomyces cerevisiae. Radiat Res 132(2):141-3