FRE1/YLR214W Literature Guide Help

Other names published for FRE1: YLR214W

FRE1 - Mutants/Phenotypes (26)

ReferenceOther Genes Addressed
North M, et al.  (2012) Genome-Wide Functional Profiling Identifies Genes and Processes Important for Zinc-Limited Growth of Saccharomyces cerevisiae. PLoS Genet 8(6):e1002699
Rinnerthaler M, et al.  (2012) Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast. Proc Natl Acad Sci U S A 109(22):8658-63
Viau CM, et al.  (2012) Enhanced resistance of yeast mutants deficient in low-affinity iron and zinc transporters to stannous-induced toxicity. Chemosphere 86(5):477-84
Ishizaki H, et al.  (2010) Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech 3(9-10):639-51
Li C, et al.  (2010) The metal chelating and chaperoning effects of clioquinol: insights from yeast studies. J Alzheimers Dis 21(4):1249-62
Shakoury-Elizeh M, et al.  (2010) Metabolic response to iron deficiency in Saccharomyces cerevisiae. J Biol Chem 285(19):14823-33
Suazo M, et al.  (2009) Overexpression of amyloid precursor protein increases copper content in HEK293 cells. Biochem Biophys Res Commun 382(4):740-4
Takahashi S, et al.  (2009) Insufficiency of copper ion homeostasis causes freeze-thaw injury of yeast cells as revealed by indirect gene expression analysis. Appl Environ Microbiol 75(21):6706-11
Herst PM, et al.  (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Ishimaru Y, et al.  (2007) From the Cover: Mutational reconstructed ferric chelate reductase confers enhanced tolerance in rice to iron deficiency in calcareous soil. Proc Natl Acad Sci U S A 104(18):7373-8
Rees EM and Thiele DJ  (2007) Identification of a vacuole-associated metalloreductase and its role in Ctr2-mediated intracellular copper mobilization. J Biol Chem 282(30):21629-38
Singh A, et al.  (2007) The metalloreductase Fre6p in Fe-efflux from the yeast vacuole. J Biol Chem 282(39):28619-26
Knight SA and Dancis A  (2006) Reduction of 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt (XTT) is dependent on CaFRE10 ferric reductase for Candida albicans grown in unbuffered media. Microbiology 152(Pt 8):2301-8
Su D and Asard H  (2006) Three mammalian cytochromes b561 are ascorbate-dependent ferrireductases. FEBS J 273(16):3722-34
Ramalho PA, et al.  (2005) Azo reductase activity of intact saccharomyces cerevisiae cells is dependent on the Fre1p component of plasma membrane ferric reductase. Appl Environ Microbiol 71(7):3882-8
van Bakel H, et al.  (2005) Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 22(3):356-67
Serrano R, et al.  (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704
Leem SH, et al.  (2003) The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. Mol Cells 15(1):55-61
Shi X, et al.  (2003) Fre1p Cu2+ reduction and Fet3p Cu1+ oxidation modulate copper toxicity in Saccharomyces cerevisiae. J Biol Chem 278(50):50309-15
Hammacott JE, et al.  (2000) Candida albicans CFL1 encodes a functional ferric reductase activity that can rescue a Saccharomyces cerevisiae fre1 mutant. Microbiology 146 ( Pt 4):869-76
Yun CW, et al.  (2000) Siderophore-iron uptake in saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters. J Biol Chem 275(21):16354-9
Georgatsou E, et al.  (1997) The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. J Biol Chem 272(21):13786-92
Lesuisse E, et al.  (1997) Cytochrome P-450 reductase is responsible for the ferrireductase activity associated with isolated plasma membranes of Saccharomyces cerevisiae. FEMS Microbiol Lett 156(1):147-52
Finegold AA, et al.  (1996) Intramembrane bis-heme motif for transmembrane electron transport conserved in a yeast iron reductase and the human NADPH oxidase. J Biol Chem 271(49):31021-4
Lesuisse E, et al.  (1996) Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transport chain. J Biol Chem 271(23):13578-83
Dancis A, et al.  (1990) Genetic evidence that ferric reductase is required for iron uptake in Saccharomyces cerevisiae. Mol Cell Biol 10(5):2294-301