ERG27/YLR100W Literature Guide Help

Other names published for ERG27: 3-keto-steroid reductase, YLR100W

ERG27 - Mutants/Phenotypes (10)

ReferenceOther Genes Addressed
Layer JV, et al.  (2013) Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway. Biochim Biophys Acta 1831(2):361-9
Taramino S, et al.  (2010) Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts. Biochim Biophys Acta 1801(11):1232-7
Taramino S, et al.  (2010) Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast. Biochim Biophys Acta 1801(2):156-162
Teske B, et al.  (2008) Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1781(8):359-66
Snoek IS and Steensma HY  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Mo C, et al.  (2003) In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. Biochim Biophys Acta 1633(1):68-74
Mo C, et al.  (2002) Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis. Proc Natl Acad Sci U S A 99(15):9739-44
Gachotte D, et al.  (1999) Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation. Proc Natl Acad Sci U S A 96(22):12655-60