PDC1/YLR044C Literature Guide Help

Other names published for PDC1: indolepyruvate decarboxylase 1, YLR044C

PDC1 - Mutants/Phenotypes (65)

ReferenceOther Genes Addressed
Jain VK, et al.  (2012) Effect of alternative NAD+-regenerating pathways on the formation of primary and secondary aroma compounds in a Saccharomyces cerevisiae glycerol-defective mutant. Appl Microbiol Biotechnol 93(1):131-41
Kondo T, et al.  (2012) Genetic engineering to enhance the Ehrlich pathway and alter carbon flux for increased isobutanol production from glucose by Saccharomyces cerevisiae. J Biotechnol 159(1-2):32-7
Ng CY, et al.  (2012) Production of 2,3-butanediol in Saccharomyces cerevisiae by in silico aided metabolic engineering. Microb Cell Fact 11(1):68
Oud B, et al.  (2012) An internal deletion in MTH1 enables growth on glucose of pyruvate-decarboxylase negative, non-fermentative Saccharomyces cerevisiae. Microb Cell Fact 11(1):131
Romagnoli G, et al.  (2012) Substrate specificity of thiamine pyrophosphate-dependent 2-oxo-acid decarboxylases in Saccharomyces cerevisiae. Appl Environ Microbiol 78(21):7538-48
Salvado Z, et al.  (2012) Functional analysis to identify genes in wine yeast adaptation to low-temperature fermentation. J Appl Microbiol 113(1):76-88
Stevenson BJ, et al.  (2012) Fermentative glycolysis with purified Escherichia coli enzymes for in vitro ATP production and evaluating an engineered enzyme. J Biotechnol 157(1):113-23
Veiga T, et al.  (2012) Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum. Eukaryot Cell 11(2):238-49
Yu KO, et al.  (2012) Improvement of ethanol yield from glycerol via conversion of pyruvate to ethanol in metabolically engineered Saccharomyces cerevisiae. Appl Biochem Biotechnol 166(4):856-65
Zhao L, et al.  (2011) [Modification of carbon flux in Sacchromyces cerevisiae to improve L-lactic acid production]. Wei Sheng Wu Xue Bao 51(1):50-8
Brochado AR, et al.  (2010) Improved vanillin production in baker's yeast through in silico design. Microb Cell Fact 9(1):84
Matsufuji Y, et al.  (2010) Transcription factor Stb5p is essential for acetaldehyde tolerance in Saccharomyces cerevisiae. J Basic Microbiol 50(5):494-8
Sauer M, et al.  (2010) 16 years research on lactic acid production with yeast - ready for the market? Biotechnol Genet Eng Rev 27():229-56
Hirasawa T, et al.  (2009) Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae. Appl Microbiol Biotechnol 84(6):1149-59
Kutter S, et al.  (2009) Covalently bound substrate at the regulatory site of yeast pyruvate decarboxylases triggers allosteric enzyme activation. J Biol Chem 284(18):12136-44
Tokuhiro K, et al.  (2009) Double mutation of the PDC1 and ADH1 genes improves lactate production in the yeast Saccharomyces cerevisiae expressing the bovine lactate dehydrogenase gene. Appl Microbiol Biotechnol 82(5):883-90
Stevenson BJ, et al.  (2008) Directed evolution of yeast pyruvate decarboxylase 1 for attenuated regulation and increased stability. Biochemistry 47(9):3013-25
Geertman JM, et al.  (2006) Physiological and genetic engineering of cytosolic redox metabolism in Saccharomyces cerevisiae for improved glycerol production. Metab Eng 8(6):532-42
Ishida N, et al.  (2006) Metabolic engineering of Saccharomyces cerevisiae for efficient production of pure L-(+)-lactic acid. Appl Biochem Biotechnol 129-132:795-807
Joseph E, et al.  (2006) Function of a conserved loop of the beta-domain, not involved in thiamin diphosphate binding, in catalysis and substrate activation in yeast pyruvate decarboxylase. Biochemistry 45(45):13517-27
Perpete P, et al.  (2006) Methionine catabolism in Saccharomyces cerevisiae. FEMS Yeast Res 6(1):48-56
Ishida N, et al.  (2005) Efficient production of L-Lactic acid by metabolically engineered Saccharomyces cerevisiae with a genome-integrated L-lactate dehydrogenase gene. Appl Environ Microbiol 71(4):1964-70
Moller K, et al.  (2004) Pyruvate decarboxylases from the petite-negative yeast Saccharomyces kluyveri. Mol Genet Genomics 270(6):558-68
Nemeria N, et al.  (2004) Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme. Biochemistry 43(21):6565-75
van Maris AJ, et al.  (2004) Directed evolution of pyruvate decarboxylase-negative Saccharomyces cerevisiae, yielding a C2-independent, glucose-tolerant, and pyruvate-hyperproducing yeast. Appl Environ Microbiol 70(1):159-66
van Maris AJ, et al.  (2004) Homofermentative lactate production cannot sustain anaerobic growth of engineered Saccharomyces cerevisiae: possible consequence of energy-dependent lactate export. Appl Environ Microbiol 70(5):2898-905
Dickinson JR, et al.  (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34
Vuralhan Z, et al.  (2003) Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae. Appl Environ Microbiol 69(8):4534-41
van Maris AJ, et al.  (2003) Overproduction of threonine aldolase circumvents the biosynthetic role of pyruvate decarboxylase in glucose-limited chemostat cultures of Saccharomyces cerevisiae. Appl Environ Microbiol 69(4):2094-9
Sergienko EA and Jordan F  (2002) New model for activation of yeast pyruvate decarboxylase by substrate consistent with the alternating sites mechanism: demonstration of the existence of two active forms of the enzyme. Biochemistry 41(12):3952-67