COX17/YLL009C Literature Guide Help

Other names published for COX17: YLL009C

COX17 - Mutants/Phenotypes (25)

ReferenceOther Genes Addressed
Blackman RK, et al.  (2012) Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. PLoS One 7(1):e29798
Cui Y, et al.  (2012) Mitochondrial release of the NADH dehydrogenase Ndi1 induces apoptosis in yeast. Mol Biol Cell 23(22):4373-82
Kojer K, et al.  (2012) Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state. EMBO J 31(14):3169-82
Aerts AM, et al.  (2011) The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans. Front Microbiol 2():47
Josse L, et al.  (2011) Transcriptomic and phenotypic analysis of the effects of T-2 toxin on Saccharomyces cerevisiae: evidence of mitochondrial involvement. FEMS Yeast Res 11(1):133-50
Hillenmeyer ME, et al.  (2010) Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action. Genome Biol 11(3):R30
Ishizaki H, et al.  (2010) Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Dis Model Mech 3(9-10):639-51
Longen S, et al.  (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68
Sideris DP, et al.  (2009) A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding. J Cell Biol 187(7):1007-22
Wood LK and Thiele DJ  (2009) Transcriptional activation in yeast in response to copper deficiency involves copper-zinc superoxide dismutase. J Biol Chem 284(1):404-13
Rigby K, et al.  (2008) Mapping the functional interaction of sco1 and cox2 in cytochrome oxidase biogenesis. J Biol Chem 283(22):15015-22
Yu L, et al.  (2008) Chemical-genetic profiling of imidazo[1,2-a]pyridines and -pyrimidines reveals target pathways conserved between yeast and human cells. PLoS Genet 4(11):e1000284
Cobine PA, et al.  (2006) The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding. J Biol Chem 281(18):12270-6
Viau C, et al.  (2006) Sensitivity to Sn(2+) of the Yeast Saccharomyces cerevisiae Depends on General Energy Metabolism, Metal Transport, Anti-Oxidative Defences, and DNA Repair. Biometals 19(6):705-14
Barros MH, et al.  (2004) COX23, a homologue of COX17, is required for cytochrome oxidase assembly. J Biol Chem 279(30):31943-7
Cobine PA, et al.  (2004) Yeast contain a non-proteinaceous pool of copper in the mitochondrial matrix. J Biol Chem 279(14):14447-55
Horng YC, et al.  (2004) Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. J Biol Chem 279(34):35334-40
Maxfield AB, et al.  (2004) Cox17 is functional when tethered to the mitochondrial inner membrane. J Biol Chem 279(7):5072-80
Serrano R, et al.  (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704
Punter FA and Glerum DM  (2003) Mutagenesis reveals a specific role for Cox17p in copper transport to cytochrome oxidase. J Biol Chem 278(33):30875-80
Balandin T and Castresana C  (2002) AtCOX17, an Arabidopsis homolog of the yeast copper chaperone COX17. Plant Physiol 129(4):1852-7
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Heaton DN, et al.  (2001) The mitochondrial copper metallochaperone Cox17 exists as an oligomeric, polycopper complex. Biochemistry 40(3):743-51
Heaton D, et al.  (2000) Mutational analysis of the mitochondrial copper metallochaperone Cox17. J Biol Chem 275(48):37582-7
Glerum DM, et al.  (1996) Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase. J Biol Chem 271(24):14504-9