MDV1/YJL112W Literature Guide Help

Other names published for MDV1: FIS2, GAG3, NET2, YJL112W

MDV1 - Mutants/Phenotypes (29)

ReferenceOther Genes Addressed
Bradshaw E, et al.  (2012) Mitochondrial fission proteins Fis1 and Mdv1, but not Dnm1, play a role in maintenance of heteroplasmy in budding yeast. FEBS Lett 586(8):1245-51
Bui HT, et al.  (2012) A novel motif in the yeast mitochondrial dynamin Dnm1 is essential for adaptor binding and membrane recruitment. J Cell Biol 199(4):613-22
Lefevre S, et al.  (2012) Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells. Biochem Biophys Res Commun 418(2):336-41
Rodley CD, et al.  (2012) Mitochondrial-nuclear DNA interactions contribute to the regulation of nuclear transcript levels as part of the inter-organelle communication system. PLoS One 7(1):e30943
Zhang Y, et al.  (2012) Crystal structure of mitochondrial fission complex reveals scaffolding function for mitochondrial division 1 (Mdv1) coiled coil. J Biol Chem 287(13):9855-61
Estela A, et al.  (2011) Charcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cells. J Biol Chem 286(42):36777-86
Mendl N, et al.  (2011) Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2. J Cell Sci 124(Pt 8):1339-50
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Bink A, et al.  (2010) A fungicidal piperazine-1-carboxamidine induces mitochondrial fission-dependent apoptosis in yeast. FEMS Yeast Res 10(7):812-8
Koirala S, et al.  (2010) Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes. J Cell Biol 191(6):1127-39
Lackner LL, et al.  (2009) Mechanistic analysis of a dynamin effector. Science 325(5942):874-7
Motley AM, et al.  (2008) Dnm1p-dependent peroxisome fission requires Caf4p, Mdv1p and Fis1p. J Cell Sci 121(Pt 10):1633-40
Nagotu S, et al.  (2008) Peroxisome fission in Hansenula polymorpha requires Mdv1 and Fis1, two proteins also involved in mitochondrial fission. Traffic 9(9):1471-84
Meisinger C, et al.  (2007) The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J 26(9):2229-39
Sanjuan Szklarz LK, et al.  (2007) Preprotein Transport Machineries of Yeast Mitochondrial Outer Membrane Are not Required for Bax-induced Release of Intermembrane Space Proteins. J Mol Biol 368(1):44-54
Wells RC, et al.  (2007) Direct binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm. J Biol Chem 282(46):33769-75
Zhang Y and Chan DC  (2007) Structural basis for recruitment of mitochondrial fission complexes by Fis1. Proc Natl Acad Sci U S A 104(47):18526-30
Naylor K, et al.  (2006) Mdv1 interacts with assembled dnm1 to promote mitochondrial division. J Biol Chem 281(4):2177-83
Schauss AC, et al.  (2006) Fis1p and Caf4p, but not Mdv1p, determine the polar localization of Dnm1p clusters on the mitochondrial surface. J Cell Sci 119(Pt 15):3098-106
Zhang NN, et al.  (2006) Multiple signaling pathways regulate yeast cell death during the response to mating pheromones. Mol Biol Cell 17(8):3409-22
Griffin EE, et al.  (2005) The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondria. J Cell Biol 170(2):237-48
Karren MA, et al.  (2005) The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly. J Cell Biol 171(2):291-301
Gorsich SW and Shaw JM  (2004) Importance of mitochondrial dynamics during meiosis and sporulation. Mol Biol Cell 15(10):4369-81
Cerveny KL and Jensen RE  (2003) The WD-repeats of Net2p interact with Dnm1p and Fis1p to regulate division of mitochondria. Mol Biol Cell 14(10):4126-39
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Cerveny KL, et al.  (2001) Division of mitochondria requires a novel DMN1-interacting protein, Net2p. Mol Biol Cell 12(2):309-21
Fekkes P, et al.  (2000) Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J Cell Biol 151(2):333-40
Mozdy AD, et al.  (2000) Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol 151(2):367-80
Tieu Q and Nunnari J  (2000) Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division. J Cell Biol 151(2):353-66