TOK1/YJL093C Literature Guide Help

Other names published for TOK1: DUK1, YKC1, YORK, YPK1, YJL093C

TOK1 - Mutants/Phenotypes (32)

ReferenceOther Genes Addressed
Zahradka J and Sychrova H  (2012) Plasma-membrane hyperpolarization diminishes the cation efflux via Nha1 antiporter and Ena ATPase under potassium-limiting conditions. FEMS Yeast Res 12(4):439-46
Zahradka J, et al.  (2012) Yeast 14-3-3 proteins participate in the regulation of cell cation homeostasis via interaction with Nha1 alkali-metal-cation/proton antiporter. Biochim Biophys Acta 1820(7):849-58
Calahorra M, et al.  (2011) Ketoconazole and miconazole alter potassium homeostasis in Saccharomyces cerevisiae. Biochim Biophys Acta 1808(1):433-45
Maresova L, et al.  (2009) Membrane hyperpolarization drives cation influx and fungicidal activity of amiodarone. J Biol Chem 284(5):2795-802
Pena A, et al.  (2009) Effects of amiodarone on K+, internal pH and Ca2+ homeostasis in Saccharomyces cerevisiae. FEMS Yeast Res 9(6):832-48
Roller A, et al.  (2008) Functional consequences of leucine and tyrosine mutations in the dual pore motifs of the yeast K(+) channel, Tok1p. Pflugers Arch 456(5):883-96
Johansson I and Blatt MR  (2006) Interactive domains between pore loops of the yeast K+ channel TOK1 associate with extracellular K+ sensitivity. Biochem J 393(Pt 3):645-55
Maresova L, et al.  (2006) Measurements of plasma membrane potential changes in Saccharomyces cerevisiae cells reveal the importance of the Tok1 channel in membrane potential maintenance. FEMS Yeast Res 6(7):1039-46
Hasenbrink G, et al.  (2005) Analysis of the mKir2.1 channel activity in potassium influx defective Saccharomyces cerevisiae strains determined as changes in growth characteristics. FEBS Lett 579(7):1723-31
Ivanovska I and Hardwick JM  (2005) Viruses activate a genetically conserved cell death pathway in a unicellular organism. J Cell Biol 170(3):391-9
Macpherson N, et al.  (2005) Plasma membrane H+ and K+ transporters are involved in the weak-acid preservative response of disparate food spoilage yeasts. Microbiology 151(Pt 6):1995-2003
Maresova L and Sychrova H  (2005) Physiological characterization of Saccharomyces cerevisiae kha1 deletion mutants. Mol Microbiol 55(2):588-600
Roller A, et al.  (2005) In the yeast potassium channel, Tok1p, the external ring of aspartate residues modulates both gating and conductance. Pflugers Arch 451(2):362-70
Proft M and Struhl K  (2004) MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction. Cell 118(3):351-61
Bertl A, et al.  (2003) Characterization of potassium transport in wild-type and isogenic yeast strains carrying all combinations of trk1, trk2 and tok1 null mutations. Mol Microbiol 47(3):767-80
Roberts SK  (2003) TOK homologue in Neurospora crassa: first cloning and functional characterization of an ion channel in a filamentous fungus. Eukaryot Cell 2(1):181-90
Breinig F, et al.  (2002) Kre1p, the plasma membrane receptor for the yeast K1 viral toxin. Cell 108(3):395-405
Erez O and Kahana C  (2002) Deletions of SKY1 or PTK2 in the Saccharomyces cerevisiae trk1Deltatrk2Delta mutant cells exert dual effect on ion homeostasis. Biochem Biophys Res Commun 295(5):1142-9
Loukin SH, et al.  (2002) The carboxyl tail forms a discrete functional domain that blocks closure of the yeast K+ channel. Proc Natl Acad Sci U S A 99(4):1926-30
Saldana C, et al.  (2002) Splitting the two pore domains from TOK1 results in two cationic channels with novel functional properties. J Biol Chem 277(7):4797-805
Sesti F, et al.  (2001) Immunity to K1 killer toxin: internal TOK1 blockade. Cell 105(5):637-44
Ahmed A, et al.  (1999) A molecular target for viral killer toxin: TOK1 potassium channels. Cell 99(3):283-91
Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
Fairman C, et al.  (1999) Potassium uptake through the TOK1 K+ channel in the budding yeast. J Membr Biol 168(2):149-57
Roberts SK, et al.  (1999) Divalent cation block of inward currents and low-affinity K+ uptake in Saccharomyces cerevisiae. J Bacteriol 181(1):291-7
Vergani P and Blatt MR  (1999) Mutations in the yeast two pore K+ channel YKC1 identify functional differences between the pore domains. FEBS Lett 458(3):285-91
Bihler H, et al.  (1998) NSC1: a novel high-current inward rectifier for cations in the plasma membrane of Saccharomyces cerevisiae. FEBS Lett 432(1-2):59-64
Vergani P, et al.  (1998) Mutations in the pore regions of the yeast K+ channel YKC1 affect gating by extracellular K+. EMBO J 17(24):7190-8
Loukin SH, et al.  (1997) Random mutagenesis reveals a region important for gating of the yeast K+ channel Ykc1. EMBO J 16(16):4817-25
Reid JD, et al.  (1996) The S. cerevisiae outwardly-rectifying potassium channel (DUK1) identifies a new family of channels with duplicated pore domains. Receptors Channels 4(1):51-62