HXK2/YGL253W Literature Guide Help

Other names published for HXK2: HEX1, HKB, SCI2, hexokinase 2, YGL253W

HXK2 - Mutants/Phenotypes (109)

ReferenceOther Genes Addressed
Riera A, et al.  (2008) Human pancreatic beta-cell glucokinase: subcellular localization and glucose repression signalling function in the yeast cell. Biochem J 415(2):233-9
Rossell S, et al.  (2008) Mixed and diverse metabolic and gene-expression regulation of the glycolytic and fermentative pathways in response to a HXK2 deletion in Saccharomyces cerevisiae. FEMS Yeast Res 8(1):155-64
Saleem RA, et al.  (2008) Genome-wide analysis of signaling networks regulating fatty acid-induced gene expression and organelle biogenesis. J Cell Biol 181(2):281-92
Schuurmans JM, et al.  (2008) Effect of hxk2 deletion and HAP4 overexpression on fermentative capacity in Saccharomyces cerevisiae. FEMS Yeast Res 8(2):195-203
Schuurmans JM, et al.  (2008) Physiological and transcriptional characterization of Saccharomyces cerevisiae strains with modified expression of catabolic regulators. FEMS Yeast Res 8(1):26-34
Van de Velde S and Thevelein JM  (2008) Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae. Eukaryot Cell 7(2):286-93
Ye T, et al.  (2008) The pathway by which the yeast protein kinase Snf1p controls acquisition of sodium tolerance is different from that mediating glucose regulation. Microbiology 154(Pt 9):2814-26
Ahuatzi D, et al.  (2007) Hxk2 regulates the phosphorylation state of Mig1 and therefore its nucleocytoplasmic distribution. J Biol Chem 282(7):4485-93
Belinchon MM and Gancedo JM  (2007) Different signalling pathways mediate glucose induction of SUC2, HXT1 and pyruvate decarboxylase in yeast. FEMS Yeast Res 7(1):40-7
Easlon E, et al.  (2007) The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension. J Biol Chem 282(9):6161-71
Sarma NJ, et al.  (2007) Glucose-responsive regulators of gene expression in Saccharomyces cerevisiae function at the nuclear periphery via a reverse recruitment mechanism. Genetics 175(3):1127-35
Smith DL Jr, et al.  (2007) Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Aging Cell 6(5):649-62
Westergaard SL, et al.  (2007) A systems biology approach to study glucose repression in the yeast Saccharomyces cerevisiae. Biotechnol Bioeng 96(1):134-45
Cho JI, et al.  (2006) Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta 224(3):598-611
Kaeberlein M, et al.  (2006) Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science 312(5778):1312; author reply 1312
Kingsbury JM, et al.  (2006) Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. Eukaryot Cell 5(5):816-24
Lee TH, et al.  (2006) Disruption of hexokinase II (HXK2) partly relieves glucose repression to enhance production of human kringle fragment in gratuitous recombinant Saccharomyces cerevisiae. J Biotechnol 126(4):562-7
Kaeberlein M and Kennedy BK  (2005) Large-scale identification in yeast of conserved ageing genes. Mech Ageing Dev 126(1):17-21
Kaeberlein M, et al.  (2005) Genes determining yeast replicative life span in a long-lived genetic background. Mech Ageing Dev 126(4):491-504
Kang HA, et al.  (2005) Characteristics of Saccharomyces cerevisiae gal1 Delta and gal1 Delta hxk2 Delta mutants expressing recombinant proteins from the GAL promoter. Biotechnol Bioeng 89(6):619-29
Lamming DW, et al.  (2005) HST2 mediates SIR2-independent life-span extension by calorie restriction. Science 309(5742):1861-4
Blank LM and Sauer U  (2004) TCA cycle activity in Saccharomyces cerevisiae is a function of the environmentally determined specific growth and glucose uptake rates. Microbiology 150(Pt 4):1085-93
Dong L and Xu CW  (2004) Carbohydrates induce mono-ubiquitination of H2B in yeast. J Biol Chem 279(3):1577-80
Hung GC, et al.  (2004) Degradation of the gluconeogenic enzymes fructose-1,6-bisphosphatase and malate dehydrogenase is mediated by distinct proteolytic pathways and signaling events. J Biol Chem 279(47):49138-50
Kaeberlein M, et al.  (2004) Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2(9):E296
Mulet JM, et al.  (2004) The trehalose pathway and intracellular glucose phosphates as modulators of potassium transport and general cation homeostasis in yeast. Yeast 21(7):569-82
Raghevendran V, et al.  (2004) Phenotypic characterization of glucose repression mutants of Saccharomyces cerevisiae using experiments with 13C-labelled glucose. Yeast 21(9):769-79
Bonini BM, et al.  (2003) Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae Tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe. Biochim Biophys Acta 1606(1-3):83-93
Giots F, et al.  (2003) Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 47(4):1163-81
Miseta A, et al.  (2003) A Saccharomyces cerevisiae mutant unable to convert glucose to glucose-6-phosphate accumulates excessive glucose in the endoplasmic reticulum due to core oligosaccharide trimming. Eukaryot Cell 2(3):534-41