XRN1/YGL173C Literature Guide Help

Other names published for XRN1: DST2, RAR5, SEP1, SKI1, KEM1, YGL173C

XRN1 - Mutants/Phenotypes (166)

ReferenceOther Genes Addressed
Prieto S, et al.  (2000) Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life. J Biol Chem 275(19):14155-66
Benard L, et al.  (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900
He W and Parker R  (1999) Analysis of mRNA decay pathways in Saccharomyces cerevisiae. Methods 17(1):3-10
Ho JH and Johnson AW  (1999) NMD3 encodes an essential cytoplasmic protein required for stable 60S ribosomal subunits in Saccharomyces cerevisiae. Mol Cell Biol 19(3):2389-99
Moy TI and Silver PA  (1999) Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes Dev 13(16):2118-33
Niepel M, et al.  (1999) Secondary structure in the 5'-leader or 3'-untranslated region reduces protein yield but does not affect the functional interaction between the 5'-cap and the poly(A) tail. FEBS Lett 462(1-2):79-84
Schwartz DC and Parker R  (1999) Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5247-56
Solinger JA, et al.  (1999) Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol 19(9):5930-42
Anderson JS and Parker RP  (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506
Lo HJ, et al.  (1998) RNA polymerase I-promoted HIS4 expression yields uncapped, polyadenylated mRNA that is unstable and inefficiently translated in Saccharomyces cerevisiae. Mol Cell Biol 18(2):665-75
McNeil JB, et al.  (1998) Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev 12(16):2510-21
Page AM, et al.  (1998) Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res 26(16):3707-16
Petfalski E, et al.  (1998) Processing of the precursors to small nucleolar RNAs and rRNAs requires common components. Mol Cell Biol 18(3):1181-9
Schwer B, et al.  (1998) Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme. Nucleic Acids Res 26(9):2050-7
Till DD, et al.  (1998) Identification and developmental expression of a 5'-3' exoribonuclease from Drosophila melanogaster. Mech Dev 79(1-2):51-5
Villa T, et al.  (1998) Processing of the intron-encoded U18 small nucleolar RNA in the yeast Saccharomyces cerevisiae relies on both exo- and endonucleolytic activities. Mol Cell Biol 18(6):3376-83
Dichtl B, et al.  (1997) Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J 16(23):7184-95
Johnson AW  (1997) Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol Cell Biol 17(10):6122-30
Gonzalez CI and Martin CE  (1996) Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript. J Biol Chem 271(42):25801-9
Hatfield L, et al.  (1996) Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae. Mol Cell Biol 16(10):5830-8
Yun DF and Sherman F  (1996) Degradation of CYC1 mRNA in the yeast Saccharomyces cerevisiae does not require translation. Proc Natl Acad Sci U S A 93(17):8895-900
Bashkirov VI, et al.  (1995) Identification of functional domains in the Sep1 protein (= Kem1, Xrn1), which is required for transition through meiotic prophase in Saccharomyces cerevisiae. Chromosoma 104(3):215-22
Interthal H, et al.  (1995) A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. EMBO J 14(6):1057-66
Johnson AW and Kolodner RD  (1995) Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol 15(5):2719-27
Liu Z, et al.  (1995) Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening. Proc Natl Acad Sci U S A 92(13):6002-6
Masison DC, et al.  (1995) Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system. Mol Cell Biol 15(5):2763-71
Muhlrad D, et al.  (1995) Turnover mechanisms of the stable yeast PGK1 mRNA. Mol Cell Biol 15(4):2145-56
Poole TL and Stevens A  (1995) Comparison of features of the RNase activity of 5'-exonuclease-1 and 5'-exonuclease-2 of Saccharomyces cerevisiae. Nucleic Acids Symp Ser (33):79-81
Song Y, et al.  (1995) ROK1, a high-copy-number plasmid suppressor of kem1, encodes a putative ATP-dependent RNA helicase in Saccharomyces cerevisiae. Gene 166(1):151-4
Tishkoff DX, et al.  (1995) The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics 139(2):495-509