Other names published for XRN1: DST2, RAR5, SEP1, SKI1, KEM1, YGL173C
XRN1 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
XRN1 - Mutants/Phenotypes (166)
| Reference | Other Genes Addressed |
|---|---|
| Prieto S, et al. (2000) Glucose-regulated turnover of mRNA and the influence of poly(A) tail length on half-life. J Biol Chem 275(19):14155-66 | |
| Benard L, et al. (1999) The ski7 antiviral protein is an EF1-alpha homolog that blocks expression of non-Poly(A) mRNA in Saccharomyces cerevisiae. J Virol 73(4):2893-900 | |
| He W and Parker R (1999) Analysis of mRNA decay pathways in Saccharomyces cerevisiae. Methods 17(1):3-10 | |
| Ho JH and Johnson AW (1999) NMD3 encodes an essential cytoplasmic protein required for stable 60S ribosomal subunits in Saccharomyces cerevisiae. Mol Cell Biol 19(3):2389-99 | |
| Moy TI and Silver PA (1999) Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes Dev 13(16):2118-33 | |
| Niepel M, et al. (1999) Secondary structure in the 5'-leader or 3'-untranslated region reduces protein yield but does not affect the functional interaction between the 5'-cap and the poly(A) tail. FEBS Lett 462(1-2):79-84 | |
| Schwartz DC and Parker R (1999) Mutations in translation initiation factors lead to increased rates of deadenylation and decapping of mRNAs in Saccharomyces cerevisiae. Mol Cell Biol 19(8):5247-56 | |
| Solinger JA, et al. (1999) Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis. Mol Cell Biol 19(9):5930-42 | |
| Anderson JS and Parker RP (1998) The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J 17(5):1497-506 | |
| Lo HJ, et al. (1998) RNA polymerase I-promoted HIS4 expression yields uncapped, polyadenylated mRNA that is unstable and inefficiently translated in Saccharomyces cerevisiae. Mol Cell Biol 18(2):665-75 | |
| McNeil JB, et al. (1998) Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. Genes Dev 12(16):2510-21 | |
| Page AM, et al. (1998) Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res 26(16):3707-16 | |
| Petfalski E, et al. (1998) Processing of the precursors to small nucleolar RNAs and rRNAs requires common components. Mol Cell Biol 18(3):1181-9 | |
| Schwer B, et al. (1998) Accelerated mRNA decay in conditional mutants of yeast mRNA capping enzyme. Nucleic Acids Res 26(9):2050-7 | |
| Till DD, et al. (1998) Identification and developmental expression of a 5'-3' exoribonuclease from Drosophila melanogaster. Mech Dev 79(1-2):51-5 | |
| Villa T, et al. (1998) Processing of the intron-encoded U18 small nucleolar RNA in the yeast Saccharomyces cerevisiae relies on both exo- and endonucleolytic activities. Mol Cell Biol 18(6):3376-83 | |
| Dichtl B, et al. (1997) Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J 16(23):7184-95 | |
| Johnson AW (1997) Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol Cell Biol 17(10):6122-30 | |
| Gonzalez CI and Martin CE (1996) Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript. J Biol Chem 271(42):25801-9 | |
| Hatfield L, et al. (1996) Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae. Mol Cell Biol 16(10):5830-8 | |
| Yun DF and Sherman F (1996) Degradation of CYC1 mRNA in the yeast Saccharomyces cerevisiae does not require translation. Proc Natl Acad Sci U S A 93(17):8895-900 | |
| Bashkirov VI, et al. (1995) Identification of functional domains in the Sep1 protein (= Kem1, Xrn1), which is required for transition through meiotic prophase in Saccharomyces cerevisiae. Chromosoma 104(3):215-22 | |
| Interthal H, et al. (1995) A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae. EMBO J 14(6):1057-66 | |
| Johnson AW and Kolodner RD (1995) Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol 15(5):2719-27 | |
| Liu Z, et al. (1995) Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening. Proc Natl Acad Sci U S A 92(13):6002-6 | |
| Masison DC, et al. (1995) Decoying the cap- mRNA degradation system by a double-stranded RNA virus and poly(A)- mRNA surveillance by a yeast antiviral system. Mol Cell Biol 15(5):2763-71 | |
| Muhlrad D, et al. (1995) Turnover mechanisms of the stable yeast PGK1 mRNA. Mol Cell Biol 15(4):2145-56 | |
| Poole TL and Stevens A (1995) Comparison of features of the RNase activity of 5'-exonuclease-1 and 5'-exonuclease-2 of Saccharomyces cerevisiae. Nucleic Acids Symp Ser (33):79-81 | |
| Song Y, et al. (1995) ROK1, a high-copy-number plasmid suppressor of kem1, encodes a putative ATP-dependent RNA helicase in Saccharomyces cerevisiae. Gene 166(1):151-4 | |
| Tishkoff DX, et al. (1995) The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics 139(2):495-509 |



