CDC34/YDR054C Literature Guide Help

Other names published for CDC34: DNA6, UBC3, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34, YDR054C

CDC34 - Mutants/Phenotypes (89)

ReferenceOther Genes Addressed
Zaidi IW, et al.  (2008) Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA. EMBO Rep 9(10):1034-40
Hwang GW  (2007) A Ubiquitin-proteasome System as a Factor that Determine the Sensitivity to Methylmercury. Yakugaku Zasshi 127(3):463-8
Hwang GW, et al.  (2007) Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4. Biochem Biophys Res Commun 363(3):873-8
Pal B, et al.  (2007) SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Mol Biol Cell 18(2):426-40
Sadowski M, et al.  (2007) Cdc34 C-terminal tail phosphorylation regulates Skp1/cullin/F-box (SCF)-mediated ubiquitination and cell cycle progression. Biochem J 405(3):569-81
Sari F, et al.  (2007) A process independent of the anaphase-promoting complex contributes to instability of the yeast S phase cyclin Clb5. J Biol Chem 282(36):26614-22
Scaglione KM, et al.  (2007) SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo. Mol Cell Biol 27(16):5860-70
Barz T, et al.  (2006) Control of methionine biosynthesis genes by protein kinase CK2-mediated phosphorylation of Cdc34. Cell Mol Life Sci 63(18):2183-90
Escobar-Henriques M, et al.  (2006) Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1. J Cell Biol 173(5):645-50
Escusa S, et al.  (2006) Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Mol Microbiol 60(4):1014-25
Hiraishi H, et al.  (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5
Jackson LP, et al.  (2006) Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6. Mol Cell Biol 26(6):2456-66
Petroski MD, et al.  (2006) Evaluation of a diffusion-driven mechanism for substrate ubiquitination by the SCF-Cdc34 ubiquitin ligase complex. Mol Cell 24(4):523-34
Varelas X, et al.  (2006) The Cdc34/SCF Ubiquitination Complex Mediates Saccharomyces cerevisiae Cell Wall Integrity. Genetics 174(4):1825-39
Yu L, et al.  (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Arnason TG, et al.  (2005) Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae. Eukaryot Cell 4(1):134-46
Block K, et al.  (2005) The acidic tail domain of human Cdc34 is required for p27Kip1 ubiquitination and complementation of a cdc34 temperature sensitive yeast strain. Cell Cycle 4(10):1421-7
Gillis AN, et al.  (2005) A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis. J Cell Biol 171(5):773-84
Horak J and Wolf DH  (2005) The ubiquitin ligase SCF(Grr1) is required for Gal2p degradation in the yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun 335(4):1185-90
Lipford JR, et al.  (2005) A putative stimulatory role for activator turnover in gene expression. Nature 438(7064):113-6
Petroski MD and Deshaies RJ  (2005) Mechanism of lysine 48-linked ubiquitin-chain synthesis by the cullin-RING ubiquitin-ligase complex SCF-Cdc34. Cell 123(6):1107-20
Purnapatre K, et al.  (2005) Glucose inhibits meiotic DNA replication through SCFGrr1p-dependent destruction of Ime2p kinase. Mol Cell Biol 25(1):440-50
Bao MZ, et al.  (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000
de Bruin RA, et al.  (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117(7):887-98
Deffenbaugh AE, et al.  (2003) Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. Cell 114(5):611-22
Ke PY, et al.  (2003) Degradation of human thymidine kinase is dependent on serine-13 phosphorylation: involvement of the SCF-mediated pathway. Biochem J 370(Pt 1):265-73
Singer T, et al.  (2003) Sit4 phosphatase is functionally linked to the ubiquitin-proteasome system. Genetics 164(4):1305-21
Varelas X, et al.  (2003) Cdc34 self-association is facilitated by ubiquitin thiolester formation and is required for its catalytic activity. Mol Cell Biol 23(15):5388-400
Wang Y, et al.  (2003) Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. J Biol Chem 278(25):22284-9