UFD2/YDL190C Literature Guide Help

Other names published for UFD2: ubiquitin-ubiquitin ligase UFD2, YDL190C

UFD2 - Mutants/Phenotypes (24)

ReferenceOther Genes Addressed
Baek GH, et al.  (2012) The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation. J Biol Chem 287(32):26788-95
Baek GH, et al.  (2011) The Cdc48 ATPase modulates the interaction between two proteolytic factors Ufd2 and Rad23. Proc Natl Acad Sci U S A 108(33):13558-63
Bohm S, et al.  (2011) Cellular functions of ufd2 and ufd3 in proteasomal protein degradation depend on cdc48 binding. Mol Cell Biol 31(7):1528-39
Liu C, et al.  (2011) Ubiquitin ligase Ufd2 is required for efficient degradation of Mps1 kinase. J Biol Chem 286(51):43660-7
Piggott N, et al.  (2011) Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation. G3 (Bethesda) 1(5):353-67
Tran JR, et al.  (2011) A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis. J Biol Chem 286(7):5744-55
Villa-Garcia MJ, et al.  (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49
Hosomi A, et al.  (2010) Identification of an Htm1 (EDEM)-dependent, Mns1-independent Endoplasmic Reticulum-associated Degradation (ERAD) Pathway in Saccharomyces cerevisiae: APPLICATION OF A NOVEL ASSAY FOR GLYCOPROTEIN ERAD. J Biol Chem 285(32):24324-34
Krick R, et al.  (2010) Cdc48/p97 and Shp1/p47 regulate autophagosome biogenesis in concert with ubiquitin-like Atg8. J Cell Biol 190(6):965-73
Liu C, et al.  (2010) Ubiquitin chain elongation enzyme Ufd2 regulates a subset of Doa10 substrates. J Biol Chem 285(14):10265-72
Qiu L, et al.  (2010) Structure and function of the PLAA/Ufd3-p97/Cdc48 complex. J Biol Chem 285(1):365-72
Zhao S and Ulrich HD  (2010) Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains. Proc Natl Acad Sci U S A 107(17):7704-9
Liu C, et al.  (2009) A genome-wide synthetic dosage lethality screen reveals multiple pathways that require the functioning of ubiquitin-binding proteins Rad23 and Dsk2. BMC Biol 7(1):75
Duennwald ML and Lindquist S  (2008) Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 22(23):3308-3319
Nakatsukasa K, et al.  (2008) Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell 132(1):101-12
Ren J, et al.  (2008) DOA1/UFD3 Plays a Role in Sorting Ubiquitinated Membrane Proteins into Multivesicular Bodies. J Biol Chem 283(31):21599-611
Rumpf S and Jentsch S  (2006) Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol Cell 21(2):261-9
Richly H, et al.  (2005) A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting. Cell 120(1):73-84
Kim I, et al.  (2004) Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis. Mol Biol Cell 15(7):3357-65
Ortolan TG, et al.  (2000) The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly. Nat Cell Biol 2(9):601-8
Koegl M, et al.  (1999) A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 96(5):635-44
Hammerle M, et al.  (1998) Proteins of newly isolated mutants and the amino-terminal proline are essential for ubiquitin-proteasome-catalyzed catabolite degradation of fructose-1,6-bisphosphatase of Saccharomyces cerevisiae. J Biol Chem 273(39):25000-5
Pukatzki S, et al.  (1998) A novel component involved in ubiquitination is required for development of Dictyostelium discoideum. J Biol Chem 273(37):24131-8
Johnson ES, et al.  (1995) A proteolytic pathway that recognizes ubiquitin as a degradation signal. J Biol Chem 270(29):17442-56