SLX5/YDL013W Literature Guide Help

Other names published for SLX5: HEX3, ULS2, SUMO-targeted ubiquitin ligase complex subunit SLX5, YDL013W

SLX5 - Mutants/Phenotypes (34)

ReferenceOther Genes Addressed
Alonso A, et al.  (2012) The yeast homologue of the microtubule-associated protein Lis1 interacts with the sumoylation machinery and a SUMO-targeted ubiquitin ligase. Mol Biol Cell 23(23):4552-66
Chang HY, et al.  (2011) Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda) 1(3):197-208
Hang M and Smith MM  (2011) Genetic Analysis Implicates the Set3/Hos2 Histone Deacetylase in the Deposition and Remodeling of Nucleosomes Containing H2A.Z. Genetics 187(4):1053-66
Mullen JR, et al.  (2011) Genetic Evidence That Polysumoylation Bypasses the Need for a SUMO-Targeted Ub Ligase. Genetics 187(1):73-87
Parnas O, et al.  (2011) Elg1, the major subunit of an alternative RFC complex, interacts with SUMO-processing proteins. Cell Cycle 10(17):2894-903
Mullen JR, et al.  (2010) Wss1 is a SUMO-dependent isopeptidase that interacts genetically with the Slx5-Slx8 SUMO-targeted ubiquitin ligase. Mol Cell Biol 30(15):3737-48
Nixon CE, et al.  (2010) Degradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathways. Genetics 185(2):497-511
Paek AL, et al.  (2010) The role of replication bypass pathways in dicentric chromosome formation in budding yeast. Genetics 186(4):1161-73
Simpson-Lavy KJ and Brandeis M  (2010) Cdk1 and SUMO Regulate Swe1 Stability. PLoS One 5(12):e15089
Xie Y, et al.  (2010) SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor. Genes Dev 24(9):893-903
Chen X, et al.  (2009) Rpb1 sumoylation in response to UV radiation or transcriptional impairment in yeast. PLoS ONE 4(4):e5267
Cook CE, et al.  (2009) The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks. Cell Cycle 8(7):1080-9
Putnam CD, et al.  (2009) Specific pathways prevent duplication-mediated genome rearrangements. Nature 460(7258):984-9
Scheifele LZ, et al.  (2009) Retrotransposon overdose and genome integrity. Proc Natl Acad Sci U S A 106(33):13927-32
Wang Z and Prelich G  (2009) Quality control of a transcriptional regulator by SUMO-targeted degradation. Mol Cell Biol 29(7):1694-706
Xiong L, et al.  (2009) Deficient SUMO attachment to Flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 microm circle plasmid. Mol Biol Cell 20(4):1241-51
Andersen MP, et al.  (2008) A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95
Darst RP, et al.  (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72
Mullen JR and Brill SJ  (2008) Activation of the Slx5-Slx8 Ubiquitin Ligase by Poly-small Ubiquitin-like Modifier Conjugates. J Biol Chem 283(29):19912-21
Shima J, et al.  (2008) Possible roles of vacuolar H(+)-ATPase and mitochondrial function in tolerance to air-drying stress revealed by genome-wide screening of Saccharomyces cerevisiae deletion strains. Yeast 25(3):179-90
Burgess RC, et al.  (2007) The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination. Mol Cell Biol 27(17):6153-62
Ii T, et al.  (2007) Stimulation of in vitro sumoylation by Slx5-Slx8: evidence for a functional interaction with the SUMO pathway. DNA Repair (Amst) 6(11):1679-91
Ii T, et al.  (2007) The yeast Slx5-Slx8 DNA integrity complex displays ubiquitin ligase activity. Cell Cycle 6(22):2800-9
Kanellis P, et al.  (2007) A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions. PLoS Genet 3(8):e134
Liao C, et al.  (2007) Genomic Screening in Vivo Reveals the Role Played by Vacuolar H+ ATPase and Cytosolic Acidification in Sensitivity to DNA-Damaging Agents Such as Cisplatin. Mol Pharmacol 71(2):416-25
Palancade B, et al.  (2007) Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes. Mol Biol Cell 18(8):2912-23
Uzunova K, et al.  (2007) Ubiquitin-dependent Proteolytic Control of SUMO Conjugates. J Biol Chem 282(47):34167-75
Xie Y, et al.  (2007) The Yeast Hex3{middle dot}Slx8 Heterodimer Is a Ubiquitin Ligase Stimulated by Substrate Sumoylation. J Biol Chem 282(47):34176-84
Azam M, et al.  (2006) Evidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence. Nucleic Acids Res 34(2):506-16
Blake D, et al.  (2006) The F-Box Protein Dia2 Overcomes Replication Impedance to Promote Genome Stability in Saccharomyces cerevisiae. Genetics 174(4):1709-27