YPT1/YFL038C Literature Guide Help

Other names published for YPT1: YP2, YFL038C

YPT1 - Mutants/Phenotypes (62)

ReferenceOther Genes Addressed
Du LL and Novick P  (2001) Yeast rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p. Mol Biol Cell 12(5):1215-26
Lee SA, et al.  (2001) Overexpression of a dominant-negative allele of YPT1 inhibits growth and aspartyl protease secretion in Candida albicans. Microbiology 147(Pt 7):1961-70
Otte S, et al.  (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18
Sacher M, et al.  (2001) TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell 7(2):433-42
Cao X and Barlowe C  (2000) Asymmetric requirements for a Rab GTPase and SNARE proteins in fusion of COPII vesicles with acceptor membranes. J Cell Biol 149(1):55-66
Finger FP and Novick P  (2000) Synthetic interactions of the post-Golgi sec mutations of Saccharomyces cerevisiae. Genetics 156(3):943-51
Matsuda N, et al.  (2000) Overexpression of PRA2, a Rab/Ypt-family small GTPase from Pea Pisum sativum, aggravates the growth defect of yeast ypt mutants. Cell Struct Funct 25(1):11-20
VanRheenen SM, et al.  (1999) Sec34p, a protein required for vesicle tethering to the yeast Golgi apparatus, is in a complex with Sec35p. J Cell Biol 147(4):729-42
Walch-Solimena C and Novick P  (1999) The yeast phosphatidylinositol-4-OH kinase pik1 regulates secretion at the Golgi. Nat Cell Biol 1(8):523-5
Yoo JS, et al.  (1999) Functional implications of genetic interactions between genes encoding small GTPases involved in vesicular transport in yeast. Mol Gen Genet 261(1):80-91
Day GJ, et al.  (1998) Distinct subclasses of small GTPases interact with guanine nucleotide exchange factors in a similar manner. Mol Cell Biol 18(12):7444-54
Jiang Y, et al.  (1998) A high copy suppressor screen reveals genetic interactions between BET3 and a new gene. Evidence for a novel complex in ER-to-Golgi transport. Genetics 149(2):833-41
Jones S, et al.  (1998) Identification of regulators for Ypt1 GTPase nucleotide cycling. Mol Biol Cell 9(10):2819-37
Li B and Warner JR  (1998) Genetic interaction between YPT6 and YPT1 in Saccharomyces cerevisiae. Yeast 14(10):915-22
Richardson CJ, et al.  (1998) GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport. Mol Cell Biol 18(2):827-38
VanRheenen SM, et al.  (1998) Sec35p, a novel peripheral membrane protein, is required for ER to Golgi vesicle docking. J Cell Biol 141(5):1107-19
Kim WY, et al.  (1996) Isolation of an additional soybean cDNA encoding Ypt/Rab-related small GTP-binding protein and its functional comparison to Sypt using a yeast ypt1-1 mutant. Plant Mol Biol 31(4):783-92
Kito M, et al.  (1996) Calcium and SLY genes suppress the temperature-sensitive secretion defect of Saccharomyces cerevisiae uso1 mutant. Biochem Biophys Res Commun 220(3):653-7
Lupashin VV, et al.  (1996) Biochemical requirements for the targeting and fusion of ER-derived transport vesicles with purified yeast Golgi membranes. J Cell Biol 132(3):277-89
Sapperstein SK, et al.  (1996) Assembly of the ER to Golgi SNARE complex requires Uso1p. J Cell Biol 132(5):755-67
Jedd G, et al.  (1995) The Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway. J Cell Biol 131(3):583-90
Jones S, et al.  (1995) Requirement of nucleotide exchange factor for Ypt1 GTPase mediated protein transport. J Cell Biol 130(5):1051-61
Ossig R, et al.  (1995) Functionality and specific membrane localization of transport GTPases carrying C-terminal membrane anchors of synaptobrevin-like proteins. EMBO J 14(15):3645-53
Becker J, et al.  (1991) Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity. EMBO J 10(4):785-92
Baker D, et al.  (1990) GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. Proc Natl Acad Sci U S A 87(1):355-9
Bacon RA, et al.  (1989) The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants. J Cell Biol 109(3):1015-22
Molenaar CM, et al.  (1988) A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein. EMBO J 7(4):971-6
Schmitt HD, et al.  (1988) Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium. Cell 53(4):635-47
Segev N, et al.  (1988) The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery. Cell 52(6):915-24
Segev N and Botstein D  (1987) The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response. Mol Cell Biol 7(7):2367-77