SIS2/YKR072C Literature Guide Help

Other names published for SIS2: HAL3, phosphopantothenoylcysteine decarboxylase complex subunit SIS2, YKR072C

SIS2 - Mutants/Phenotypes (28)

ReferenceOther Genes Addressed
Delaney JR, et al.  (2013) Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell 12(1):156-66
Abrie JA, et al.  (2012) Functional mapping of the disparate activities of the yeast moonlighting protein Hal3. Biochem J 442(2):357-68
Marquina M, et al.  (2012) Modulation of yeast alkaline cation tolerance by Ypi1 requires calcineurin. Genetics 190(4):1355-64
Zaidi I, et al.  (2012) The wheat MAP kinase phosphatase 1 confers higher lithium tolerance in yeast. FEMS Yeast Res 12(7):774-84
Delaney JR, et al.  (2011) Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle 10(1):156-65
Fell GL, et al.  (2011) Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda) 1(1):43-56
Merchan S, et al.  (2011) Genetic alterations leading to increases in internal potassium concentrations are detrimental for DNA integrity in Saccharomyces cerevisiae. Genes Cells 16(2):152-65
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Ivanov MS, et al.  (2010) [The protein complex Ppz1p/Hal3p and nonsense suppression efficiency in the yeast Saccharomyces cerevisiae]. Mol Biol (Mosk) 44(6):1018-26
Ruiz A, et al.  (2009) Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nat Chem Biol 5(12):920-8
Ruotolo R, et al.  (2008) Membrane transporters and protein traffic networks differentially affecting metal tolerance: a genomic phenotyping study in yeast. Genome Biol 9(4):R67
Smith ED, et al.  (2008) Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Res 18(4):564-70
Aksenova A, et al.  (2007) The HAL3-PPZ1 dependent regulation of nonsense suppression efficiency in yeast and its influence on manifestation of the yeast prion-like determinant [ISP(+)]. Genes Cells 12(4):435-45
Ruiz A, et al.  (2006) Role of protein phosphatases 2C on tolerance to lithium toxicity in the yeast Saccharomyces cerevisiae. Mol Microbiol 62(1):263-77
Begley TJ, et al.  (2004) Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. Mol Cell 16(1):117-25
Munoz I, et al.  (2004) Functional characterization of the yeast Ppz1 phosphatase inhibitory subunit Hal3: a mutagenesis study. J Biol Chem 279(41):42619-27
Riles L, et al.  (2004) Large-scale screening of yeast mutants for sensitivity to the IMP dehydrogenase inhibitor 6-azauracil. Yeast 21(3):241-8
Ruiz A, et al.  (2004) Functional characterization of the Saccharomyces cerevisiae VHS3 gene: a regulatory subunit of the Ppz1 protein phosphatase with novel, phosphatase-unrelated functions. J Biol Chem 279(33):34421-30
Munoz I, et al.  (2003) Identification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae. Yeast 20(2):157-69
Simon E, et al.  (2003) Mutagenesis analysis of the yeast Nha1 Na+/H+ antiporter carboxy-terminal tail reveals residues required for function in cell cycle. FEBS Lett 545(2-3):239-45
de Nadal E, et al.  (2001) A role for the Ppz Ser/Thr protein phosphatases in the regulation of translation elongation factor 1Balpha. J Biol Chem 276(18):14829-34
Clotet J, et al.  (1999) The yeast ser/thr phosphatases sit4 and ppz1 play opposite roles in regulation of the cell cycle. Mol Cell Biol 19(3):2408-15
Hemenway CS and Heitman J  (1999) Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. Mol Gen Genet 261(2):388-401
de Nadal E, et al.  (1999) Biochemical and genetic analyses of the role of yeast casein kinase 2 in salt tolerance. J Bacteriol 181(20):6456-62
Masson JY and Ramotar D  (1998) The transcriptional activator Imp2p maintains ion homeostasis in Saccharomyces cerevisiae. Genetics 149(2):893-901
de Nadal E, et al.  (1998) The yeast halotolerance determinant Hal3p is an inhibitory subunit of the Ppz1p Ser/Thr protein phosphatase. Proc Natl Acad Sci U S A 95(13):7357-62
Rios G, et al.  (1997) Mechanisms of salt tolerance conferred by overexpression of the HAL1 gene in Saccharomyces cerevisiae. Yeast 13(6):515-28
Ferrando A, et al.  (1995) Regulation of cation transport in Saccharomyces cerevisiae by the salt tolerance gene HAL3. Mol Cell Biol 15(10):5470-81