SAC1/YKL212W Literature Guide Help

Other names published for SAC1: RSD1, phosphatidylinositol-3-phosphatase SAC1, YKL212W

SAC1 - Mutants/Phenotypes (75)

ReferenceOther Genes Addressed
Chen J, et al.  (2012) Accumulation of an antidepressant in vesiculogenic membranes of yeast cells triggers autophagy. PLoS One 7(4):e34024
Piao H, et al.  (2012) Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi. Traffic 13(11):1522-31
Wilmes A, et al.  (2012) Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae. Gene 497(2):140-6
Zhong S, et al.  (2012) Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids. Biochemistry 51(15):3170-7
Alfaro G, et al.  (2011) The sterol-binding protein Kes1/Osh4p is a regulator of polarized exocytosis. Traffic 12(11):1521-36
Fell GL, et al.  (2011) Identification of yeast genes involved in k homeostasis: loss of membrane traffic genes affects k uptake. G3 (Bethesda) 1(1):43-56
Kitagawa T, et al.  (2011) Identification of genes that enhance cellulase protein production in yeast. J Biotechnol 151(2):194-203
Lorente-Rodriguez A and Barlowe C  (2011) Requirement for Golgi-localized PI(4)P in fusion of COPII vesicles with Golgi compartments. Mol Biol Cell 22(2):216-29
Manogaran AL, et al.  (2011) Prion formation and polyglutamine aggregation are controlled by two classes of genes. PLoS Genet 7(5):e1001386
Minear S, et al.  (2011) Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Eukaryot Cell 10(11):1574-81
Santiago-Tirado FH, et al.  (2011) PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast. Dev Cell 20(1):47-59
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Stefan CJ, et al.  (2011) Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites. Cell 144(3):389-401
Uluisik I, et al.  (2011) Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics 97(2):106-11
Villa-Garcia MJ, et al.  (2011) Genome-wide screen for inositol auxotrophy in Saccharomyces cerevisiae implicates lipid metabolism in stress response signaling. Mol Genet Genomics 285(2):125-49
Banuelos MG, et al.  (2010) Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae. Curr Genet 56(2):121-37
Breslow DK, et al.  (2010) Orm family proteins mediate sphingolipid homeostasis. Nature 463(7284):1048-53
Hacioglu E, et al.  (2010) The roles of thiol oxidoreductases in yeast replicative aging. Mech Ageing Dev 131(11-12):692-9
James AM, et al.  (2010) Complementation of coenzyme Q-deficient yeast by coenzyme Q analogues requires the isoprenoid side chain. FEBS J 277(9):2067-82
Manford A, et al.  (2010) Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function. EMBO J 29(9):1489-98
Mizuno-Yamasaki E, et al.  (2010) Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p. Dev Cell 18(5):828-40
Puts CF, et al.  (2010) A P(4)-ATPase Protein Interaction Network Reveals a Link between Aminophospholipid Transport and Phosphoinositide Metabolism. J Proteome Res 9(2):833-42
Tani M and Kuge O  (2010) Requirement of a specific group of sphingolipid-metabolizing enzyme for growth of yeast Saccharomyces cerevisiae under impaired metabolism of glycerophospholipids. Mol Microbiol 78(2):395-413
Aghamohammadzadeh S and Ayscough KR  (2009) Differential requirements for actin during yeast and mammalian endocytosis. Nat Cell Biol 11(8):1039-42
Brice SE, et al.  (2009) Modulation of Sphingolipid Metabolism by the Phosphatidylinositol-4-phosphate Phosphatase Sac1p through Regulation of Phosphatidylinositol in Saccharomyces cerevisiae. J Biol Chem 284(12):7588-96
Gaillard H, et al.  (2009) Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair. PLoS Genet 5(2):e1000364
Muthusamy BP, et al.  (2009) Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue. Mol Biol Cell 20(12):2920-31
Wood CS, et al.  (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol 187(7):967-75
Yakir-Tamang L and Gerst JE  (2009) A phosphatidylinositol-transfer protein and phosphatidylinositol-4-phosphate 5-kinase control Cdc42 to regulate the actin cytoskeleton and secretory pathway in yeast. Mol Biol Cell 20(15):3583-97
Abe F and Minegishi H  (2008) Global screening of genes essential for growth in high-pressure and cold environments: searching for basic adaptive strategies using a yeast deletion library. Genetics 178(2):851-72