RAD27/YKL113C Literature Guide Help

Other names published for RAD27: ERC11, RTH1, FEN1, YKL113C

RAD27 - Mutants/Phenotypes (145)

ReferenceOther Genes Addressed
Moreau S, et al.  (1999) The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol Cell Biol 19(1):556-66
Parenteau J and Wellinger RJ  (1999) Accumulation of single-stranded DNA and destabilization of telomeric repeats in yeast mutant strains carrying a deletion of RAD27. Mol Cell Biol 19(6):4143-52
Qiu J, et al.  (1999) Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease. Mol Cell Biol 19(12):8361-71
Richard GF, et al.  (1999) Double-strand break repair can lead to high frequencies of deletions within short CAG/CTG trinucleotide repeats. Mol Gen Genet 261(4-5):871-82
White PJ, et al.  (1999) Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism. Mol Cell Biol 19(8):5675-84
Wu X and Wang Z  (1999) Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA. Nucleic Acids Res 27(4):956-62
Wu X, et al.  (1999) A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events. Proc Natl Acad Sci U S A 96(4):1303-8
Xie Y, et al.  (1999) Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader. Genetics 151(2):499-509
Bibikova M, et al.  (1998) Characterization of FEN-1 from Xenopus laevis. cDNA cloning and role in DNA metabolism. J Biol Chem 273(51):34222-9
Frank G, et al.  (1998) Partial functional deficiency of E160D flap endonuclease-1 mutant in vitro and in vivo is due to defective cleavage of DNA substrates. J Biol Chem 273(49):33064-72
Freudenreich CH, et al.  (1998) Expansion and length-dependent fragility of CTG repeats in yeast. Science 279(5352):853-6
Johnson RE, et al.  (1998) Role of yeast Rth1 nuclease and its homologs in mutation avoidance, DNA repair, and DNA replication. Curr Genet 34(1):21-9
Kokoska RJ, et al.  (1998) Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). Mol Cell Biol 18(5):2779-88
Maurer DJ, et al.  (1998) Mapping the polarity of changes that occur in interrupted CAG repeat tracts in yeast. Mol Cell Biol 18(8):4597-604
Merrill BJ and Holm C  (1998) The RAD52 recombinational repair pathway is essential in pol30 (PCNA) mutants that accumulate small single-stranded DNA fragments during DNA synthesis. Genetics 148(2):611-24
Schweitzer JK and Livingston DM  (1998) Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum Mol Genet 7(1):69-74
Symington LS  (1998) Homologous recombination is required for the viability of rad27 mutants. Nucleic Acids Res 26(24):5589-95
Tishkoff DX, et al.  (1998) Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. Cancer Res 58(22):5027-31
Budd ME and Campbell JL  (1997) A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function. Mol Cell Biol 17(4):2136-42
Tishkoff DX, et al.  (1997) A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell 88(2):253-63
Tishkoff DX, et al.  (1997) Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A 94(14):7487-92
Johnson RE, et al.  (1995) Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA. Science 269(5221):238-40
Reagan MS, et al.  (1995) Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene. J Bacteriol 177(2):364-71
Sommers CH, et al.  (1995) Conditional lethality of null mutations in RTH1 that encodes the yeast counterpart of a mammalian 5'- to 3'-exonuclease required for lagging strand DNA synthesis in reconstituted systems. J Biol Chem 270(9):4193-6
Vallen EA and Cross FR  (1995) Mutations in RAD27 define a potential link between G1 cyclins and DNA replication. Mol Cell Biol 15(8):4291-302