TIM44/YIL022W Literature Guide Help

Other names published for TIM44: ISP45, MIM44, MPI1, YIL022W

TIM44 - Mutants/Phenotypes (21)

ReferenceOther Genes Addressed
Schilke BA, et al.  (2012) Genetic analysis of complex interactions among components of the mitochondrial import motor and translocon in Saccharomyces cerevisiae. Genetics 190(4):1341-53
Cui W, et al.  (2011) Membrane binding mechanism of yeast mitochondrial peripheral membrane protein TIM44. Protein Pept Lett 18(7):718-25
Hayashi M, et al.  (2011) Ancient gene duplication provided a key molecular step for anaerobic growth of Baker's yeast. Mol Biol Evol 28(7):2005-17
Schiller D  (2009) Pam17 and Tim44 act sequentially in protein import into the mitochondrial matrix. Int J Biochem Cell Biol 41(11):2343-9
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
D'Silva PR, et al.  (2008) Interaction of the J-protein heterodimer Pam18/Pam16 of the mitochondrial import motor with the translocon of the inner membrane. Mol Biol Cell 19(1):424-32
Hutu DP, et al.  (2008) Mitochondrial protein import motor: differential role of tim44 in the recruitment of pam17 and j-complex to the presequence translocase. Mol Biol Cell 19(6):2642-9
Schiller D, et al.  (2008) Residues of Tim44 involved in both association with the translocon of the inner mitochondrial membrane and regulation of mitochondrial Hsp70 tethering. Mol Cell Biol 28(13):4424-33
Krayl M, et al.  (2007) A cooperative action of the ATP-dependent import motor complex and the inner membrane potential drives mitochondrial preprotein import. Mol Cell Biol 27(2):411-25
Slutsky-Leiderman O, et al.  (2007) The interplay between components of the mitochondrial protein translocation motor studied using purified components. J Biol Chem 282(47):33935-42
Meinecke M, et al.  (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6
Burri L, et al.  (2004) Zim17, a novel zinc finger protein essential for protein import into mitochondria. J Biol Chem 279(48):50243-9
Milisav I, et al.  (2001) Modular structure of the TIM23 preprotein translocase of mitochondria. J Biol Chem 276(28):25856-61
Merlin A, et al.  (1999) The J-related segment of tim44 is essential for cell viability: a mutant Tim44 remains in the mitochondrial import site, but inefficiently recruits mtHsp70 and impairs protein translocation. J Cell Biol 145(5):961-72
Weiss C, et al.  (1999) Domain structure and lipid interaction of recombinant yeast Tim44. Proc Natl Acad Sci U S A 96(16):8890-4
Bomer U, et al.  (1998) Separation of structural and dynamic functions of the mitochondrial translocase: Tim44 is crucial for the inner membrane import sites in translocation of tightly folded domains, but not of loosely folded preproteins. EMBO J 17(15):4226-37
Bomer U, et al.  (1997) Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane. EMBO J 16(9):2205-16
Blom J, et al.  (1995) Functional and physical interactions of components of the yeast mitochondrial inner-membrane import machinery (MIM). Eur J Biochem 232(1):309-14
Rassow J, et al.  (1994) Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix hsp70 and the inner membrane protein MIM44. J Cell Biol 127(6 Pt 1):1547-56
Dekker PJ, et al.  (1993) Identification of MIM23, a putative component of the protein import machinery of the mitochondrial inner membrane. FEBS Lett 330(1):66-70
Maarse AC, et al.  (1992) MPI1, an essential gene encoding a mitochondrial membrane protein, is possibly involved in protein import into yeast mitochondria. EMBO J 11(10):3619-28