ERG7/YHR072W Literature Guide Help

Other names published for ERG7: lanosterol synthase ERG7, YHR072W

ERG7 - Mutants/Phenotypes (41)

Results: 1 - 30 of 41 records
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ReferenceOther Genes Addressed
Gerstein AC  (2013) Mutational effects depend on ploidy level: all else is not equal. Biol Lett 9(1):20120614
Layer JV, et al.  (2013) Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway. Biochim Biophys Acta 1831(2):361-9
Chang CH, et al.  (2012) The cysteine 703 to isoleucine or histidine mutation of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae generates an iridal-type triterpenoid. Biochimie 94(11):2376-81
Gerstein AC, et al.  (2012) Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeast. Genetics 192(1):241-52
Liu YT, et al.  (2012) Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase. Org Lett 14(20):5222-5
Ta TM, et al.  (2012) Accumulation of squalene is associated with the clustering of lipid droplets. FEBS J 279(22):4231-44
Oliaro-Bosso S, et al.  (2011) Characterization of the channel constriction allowing the access of the substrate to the active site of yeast oxidosqualene cyclase. PLoS One 6(7):e22134
Wallace IM, et al.  (2011) Compound prioritization methods increase rates of chemical probe discovery in model organisms. Chem Biol 18(10):1273-83
Wu TK, et al.  (2011) Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17alpha/beta-exocyclic side chain stereochemistry. Org Biomol Chem 9(4):1092-7
Joffrion TM, et al.  (2010) Functional characterization and localization of Pneumocystis carinii lanosterol synthase. Eukaryot Cell 9(1):107-15
Taramino S, et al.  (2010) Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast. Biochim Biophys Acta 1801(2):156-162
Wu TK, et al.  (2010) Alteration of the Substrate's Prefolded Conformation and Cyclization Stereochemistry of Oxidosqualene-Lanosterol Cyclase of Saccharomyces cerevisiae by Substitution at Phenylalanine 699. Org Lett 12(3):500-3
Teske B, et al.  (2008) Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1781(8):359-66
Wu TK, et al.  (2008) Importance of Saccharomyces cerevisiae Oxidosqualene-Lanosterol Cyclase Tyrosine 707 Residue for Chair-Boat Bicyclic Ring Formation and Deprotonation Reactions. Org Lett 10(21):4959-62
Wu TK, et al.  (2008) Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product. Org Lett 10(12):2529-32
Basyuni M, et al.  (2007) Cloning and Functional Expression of Cycloartenol Synthases from Mangrove Species Rhizophora stylosa Griff. and Kandelia candel (L.) Druce. Biosci Biotechnol Biochem 71(7):1788-92
Sawai S, et al.  (2006) Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes. Plant Cell Physiol 47(5):673-7
Snoek IS and Steensma HY  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
Tansakul P, et al.  (2006) Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng. FEBS Lett 580(22):5143-9
Wu TK, et al.  (2006) Phenylalanine 445 within Oxidosqualene-Lanosterol Cyclase from Saccharomyces cerevisiae Influences C-Ring Cyclization and Deprotonation Reactions. Org Lett 8(21):4691-4
Wu TK, et al.  (2006) Site-Saturated Mutagenesis of Histidine 234 of Saccharomyces cerevisiae Oxidosqualene-Lanosterol Cyclase Demonstrates Dual Functions in Cyclization and Rearrangement Reactions. J Am Chem Soc 128(19):6414-9
Wu TK, et al.  (2006) Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions. Org Lett 8(7):1319-22
Altmann K and Westermann B  (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7
Buurman ET, et al.  (2005) Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. Antimicrob Agents Chemother 49(6):2558-60
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Germann M, et al.  (2005) Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. J Biol Chem 280(43):35904-13
Oliaro-Bosso S, et al.  (2005) Access of the Substrate to the Active Site of Yeast Oxidosqualene Cyclase: An Inhibition and Site-Directed Mutagenesis Approach. Chembiochem 6(12):2221-2228
Lum PY, et al.  (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37
Mullner H, et al.  (2004) Targeting of proteins involved in sterol biosynthesis to lipid particles of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta 1663(1-2):9-13
Milla P, et al.  (2002) Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles. J Biol Chem 277(4):2406-12
Results: 1 - 30 of 41 records
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