ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Mutants/Phenotypes (44)

Results: 1 - 30 of 44 records
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ReferenceOther Genes Addressed
Fiori A and Van Dijck P  (2012) Potent synergistic effect of doxycycline with fluconazole against Candida albicans is mediated by interference with iron homeostasis. Antimicrob Agents Chemother 56(7):3785-96
Hoepfner D, et al.  (2012) An integrated approach for identification and target validation of antifungal compounds active against Erg11p. Antimicrob Agents Chemother 56(8):4233-40
Hornung G, et al.  (2012) Noise-mean relationship in mutated promoters. Genome Res 22(12):2409-17
Hull CM, et al.  (2012) Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B. Antimicrob Agents Chemother 56(8):4223-32
Alcazar-Fuoli L, et al.  (2011) Three-dimensional models of 14a-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction. Int J Antimicrob Agents 38(5):426-34
Nkinin SW, et al.  (2011) Pneumocystis carinii sterol 14a-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. J Eukaryot Microbiol 58(4):383-92
Spitzer M, et al.  (2011) Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Mol Syst Biol 7():499
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Hoon S, et al.  (2008) An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol 4(8):498-506
Paluszynski JP, et al.  (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology 154(Pt 10):3154-64
Warrilow A, et al.  (2008) Expression and Characterization of CYP51, the Ancient Sterol 14-demethylase Activity for Cytochromes P450 (CYP), in the White-Rot Fungus Phanerochaete chrysosporium. Lipids 43(12):1143-53
Wu TK, et al.  (2008) Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product. Org Lett 10(12):2529-32
Buurman ET, et al.  (2005) Utilization of target-specific, hypersensitive strains of Saccharomyces cerevisiae to determine the mode of action of antifungal compounds. Antimicrob Agents Chemother 49(6):2558-60
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Flaherty P, et al.  (2005) A latent variable model for chemogenomic profiling. Bioinformatics 21(15):3286-93
Mallory JC, et al.  (2005) Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae. Mol Cell Biol 25(5):1669-79
Ott RG, et al.  (2005) Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. Biochim Biophys Acta 1735(2):111-8
Giaever G, et al.  (2004) Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. Proc Natl Acad Sci U S A 101(3):793-8
Lum PY, et al.  (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37
Buckner FS, et al.  (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol 132(2):75-81
Morales IJ, et al.  (2003) Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. Am J Respir Cell Mol Biol 29(2):232-8
Veen M, et al.  (2003) Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. FEMS Yeast Res 4(1):87-95
Homma K, et al.  (2000) Evidence for recycling of cytochrome P450 sterol 14-demethylase from the cis-Golgi compartment to the endoplasmic reticulum (ER) upon saturation of the ER-retention mechanism. J Biochem 127(5):747-54
Launhardt H and Munder T  (2000) Post-translational regulation of Saccharomyces cerevisiae proteins tagged with the hormone-binding domains of mammalian nuclear receptors. Mol Gen Genet 264(3):317-24
Giaever G, et al.  (1999) Genomic profiling of drug sensitivities via induced haploinsufficiency. Nat Genet 21(3):278-83
Kontoyiannis DP, et al.  (1999) Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae. Antimicrob Agents Chemother 43(11):2798-800
Launhardt H, et al.  (1998) Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Yeast 14(10):935-42
Kelly SL, et al.  (1995) Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol. Biochem Biophys Res Commun 207(3):910-5
Bard M, et al.  (1993) Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans. Lipids 28(11):963-7
Doignon F, et al.  (1993) Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker. Plasmid 30(3):224-33
Results: 1 - 30 of 44 records
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