GCN4/YEL009C Literature Guide Help

Other names published for GCN4: AAS3, ARG9, AAS101, YEL009C

GCN4 - Mutants/Phenotypes (209)

ReferenceOther Genes Addressed
Greenfield NJ, et al.  (1998) The structure of the N-terminus of striated muscle alpha-tropomyosin in a chimeric peptide: nuclear magnetic resonance structure and circular dichroism studies. Biochemistry 37(21):7834-43
Marton MJ, et al.  (1998) Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat Med 4(11):1293-301
Spek EJ, et al.  (1998) Surface salt bridges stabilize the GCN4 leucine zipper. Protein Sci 7(11):2431-7
Strauss-Soukup JK and Maher LJ 3rd  (1998) Electrostatic effects in DNA bending by GCN4 mutants. Biochemistry 37(4):1060-6
Suckow M and Hollenberg CP  (1998) The activation specificities of wild-type and mutant Gcn4p in vivo can be different from the DNA binding specificities of the corresponding bZip peptides in vitro. J Mol Biol 276(5):887-902
Alenin VV and Getsova ML  (1997) [A simple method of selecting Saccharomyces cerevisiae ade1 and ade2 mutants] Genetika 33(6):858-61
Drees BL, et al.  (1997) The GCN4 leucine zipper can functionally substitute for the heat shock transcription factor's trimerization domain. J Mol Biol 273(1):61-74
Fernandes L, et al.  (1997) Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol 17(12):6982-93
Springer C, et al.  (1997) Regulation of the yeast HIS7 gene by the global transcription factor Abf1p. Mol Gen Genet 256(2):136-46
Strauss-Soukup JK and Maher LJ 3rd  (1997) DNA bending by GCN4 mutants bearing cationic residues. Biochemistry 36(33):10026-32
Wanke C, et al.  (1997) The Aspergillus niger GCN4 homologue, cpcA, is transcriptionally regulated and encodes an unusual leucine zipper. Mol Microbiol 23(1):23-33
Zeng X, et al.  (1997) Oligomerization properties of GCN4 leucine zipper e and g position mutants. Protein Sci 6(10):2218-26
Erickson FL and Hannig EM  (1996) Ligand interactions with eukaryotic translation initiation factor 2: role of the gamma-subunit. EMBO J 15(22):6311-20
Gonzalez L Jr, et al.  (1996) Buried polar residues and structural specificity in the GCN4 leucine zipper. Nat Struct Biol 3(12):1011-8
Gonzalez L Jr, et al.  (1996) Crystal structures of a single coiled-coil peptide in two oligomeric states reveal the basis for structural polymorphism. Nat Struct Biol 3(12):1002-9
Jackson BM, et al.  (1996) Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation. Mol Cell Biol 16(10):5557-71
Lindsley JE  (1996) Intradimerically tethered DNA topoisomerase II is catalytically active in DNA transport. Proc Natl Acad Sci U S A 93(7):2975-80
Ruiz-Echevarria MJ and Peltz SW  (1996) Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay. EMBO J 15(11):2810-9
Suckow M, et al.  (1996) Mutant bZip-DNA complexes with four quasi-identical protein-DNA interfaces. EMBO J 15(3):598-606
Drysdale CM, et al.  (1995) The transcriptional activator GCN4 contains multiple activation domains that are critically dependent on hydrophobic amino acids. Mol Cell Biol 15(3):1220-33
Egli CM, et al.  (1995) A complex unidirectional signal element mediates GCN4 mRNA 3' end formation in Saccharomyces cerevisiae. Mol Cell Biol 15(5):2466-73
Grant CM, et al.  (1995) Sequences 5' of the first upstream open reading frame in GCN4 mRNA are required for efficient translational reinitiation. Nucleic Acids Res 23(19):3980-8
Holdsworth MJ, et al.  (1995) The maize transcription factor Opaque-2 activates a wheat glutenin promoter in plant and yeast cells. Plant Mol Biol 29(4):711-20
O'Connell KF, et al.  (1995) Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription. Mol Cell Biol 15(4):1879-88
Romano PR, et al.  (1995) Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae. Mol Cell Biol 15(1):365-78
Tavernarakis N and Thireos G  (1995) Transcriptional interference caused by GCN4 overexpression reveals multiple interactions mediating transcriptional activation. Mol Gen Genet 247(5):571-8
DeLano WL and Brunger AT  (1994) Helix packing in proteins: prediction and energetic analysis of dimeric, trimeric, and tetrameric GCN4 coiled coil structures. Proteins 20(2):105-23
Delbecq P, et al.  (1994) A segment of mRNA encoding the leader peptide of the CPA1 gene confers repression by arginine on a heterologous yeast gene transcript. Mol Cell Biol 14(4):2378-90
Diallinas G and Thireos G  (1994) Genetic and biochemical evidence for yeast GCN2 protein kinase polymerization. Gene 143(1):21-7
Grant CM, et al.  (1994) Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron. Mol Cell Biol 14(4):2616-28