GCN4/YEL009C Literature Guide Help

Other names published for GCN4: AAS3, ARG9, AAS101, YEL009C

GCN4 - Mutants/Phenotypes (209)

ReferenceOther Genes Addressed
Vitiello SP, et al.  (2007) Absence of Btn1p in the yeast model for juvenile Batten disease may cause arginine to become toxic to yeast cells. Hum Mol Genet 16(9):1007-16
Chua G, et al.  (2006) Identifying transcription factor functions and targets by phenotypic activation. Proc Natl Acad Sci U S A 103(32):12045-50
Deng Y, et al.  (2006) Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure 14(2):247-55
Kim Y, et al.  (2006) Activation of Saccharomyces cerevisiae HIS3 results in Gcn4p-dependent, SWI/SNF-dependent mobilization of nucleosomes over the entire gene. Mol Cell Biol 26(22):8607-22
Kingsbury JM, et al.  (2006) Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. Eukaryot Cell 5(5):816-24
Liu J, et al.  (2006) A seven-helix coiled coil. Proc Natl Acad Sci U S A 103(42):15457-62
Qiu H, et al.  (2006) The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II. Mol Cell Biol 26(8):3135-48
Scherens B, et al.  (2006) Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term. FEMS Yeast Res 6(5):777-91
Son S, et al.  (2006) Stabilization of bzip peptides through incorporation of fluorinated aliphatic residues. Chembiochem 7(8):1251-7
Todeschini AL, et al.  (2006) Sodium-induced GCN4 expression controls the accumulation of the 5' to 3' RNA degradation inhibitor, 3'-phosphoadenosine 5'-phosphate. J Biol Chem 281(6):3276-82
Workman CT, et al.  (2006) A systems approach to mapping DNA damage response pathways. Science 312(5776):1054-9
Conesa C, et al.  (2005) Modulation of yeast genome expression in response to defective RNA polymerase III-dependent transcription. Mol Cell Biol 25(19):8631-42
Fishburn J, et al.  (2005) Function of a eukaryotic transcription activator during the transcription cycle. Mol Cell 18(3):369-78
Govind CK, et al.  (2005) Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo. Mol Cell Biol 25(13):5626-38
Kim SJ, et al.  (2005) Activator Gcn4p and Cyc8p/Tup1p are interdependent for promoter occupancy at ARG1 in vivo. Mol Cell Biol 25(24):11171-83
Lipford JR, et al.  (2005) A putative stimulatory role for activator turnover in gene expression. Nature 438(7064):113-6
Magazinnik T, et al.  (2005) Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast. Nucleic Acids Res 33(14):4584-92
Menon BB, et al.  (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54
Qiu H, et al.  (2005) Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p. Mol Cell Biol 25(9):3461-74
Subramanian M, et al.  (2005) Transcriptional regulation of the one-carbon metabolism regulon in Saccharomyces cerevisiae by Bas1p. Mol Microbiol 57(1):53-69
Yang L and Schepartz A  (2005) Relationship between folding and function in a sequence-specific miniature DNA-binding protein. Biochemistry 44(20):7469-78
Benard L  (2004) Inhibition of 5' to 3' mRNA degradation under stress conditions in Saccharomyces cerevisiae: from GCN4 to MET16. RNA 10(3):458-68
Gunji W, et al.  (2004) Global analysis of the regulatory network structure of gene expression in Saccharomyces cerevisiae. DNA Res 11(3):163-77
Kandror O, et al.  (2004) Yeast adapt to near-freezing temperatures by STRE/Msn2,4-dependent induction of trehalose synthesis and certain molecular chaperones. Mol Cell 13(6):771-81
Patil CK, et al.  (2004) Gcn4p and novel upstream activating sequences regulate targets of the unfolded protein response. PLoS Biol 2(8):E246
Singh CR, et al.  (2004) Physical association of eukaryotic initiation factor (eIF) 5 carboxyl-terminal domain with the lysine-rich eIF2beta segment strongly enhances its binding to eIF3. J Biol Chem 279(48):49644-55
Blanco JB, et al.  (2003) A synthetic miniprotein that binds specific DNA sequences by contacting both the major and the minor groove. Chem Biol 10(8):713-22
Eastwood EL and Schaus SE  (2003) Borrelidin induces the transcription of amino acid biosynthetic enzymes via a GCN4-dependent pathway. Bioorg Med Chem Lett 13(13):2235-7
Nishizawa M, et al.  (2003) Artificial oncoproteins: modified versions of the yeast bZip protein GCN4 induce cellular transformation. Oncogene 22(39):7931-41
Rodriguez-Hernandez CJ, et al.  (2003) The immunosuppressant FK506 uncovers a positive regulatory cross-talk between the Hog1p and Gcn2p pathways. J Biol Chem 278(36):33887-95