CHK1/YBR274W Literature Guide Help

Other names published for CHK1: YBR274W

CHK1 - Mutants/Phenotypes (65)

ReferenceOther Genes Addressed
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Eapen VV, et al.  (2012) The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation. Mol Cell Biol 32(22):4727-40
Yu S, et al.  (2012) Compromised cellular responses to DNA damage accelerate chronological aging by incurring cell wall fragility in Saccharomyces cerevisiae. Mol Biol Rep 39(4):3573-83
Chang HY, et al.  (2011) Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda) 1(3):197-208
Chen X, et al.  (2011) Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.LID - 10.1038/nsmb.2105 [doi] Nat Struct Mol Biol ()
Gehlen LR, et al.  (2011) Nuclear geometry and rapid mitosis ensure asymmetric episome segregation in yeast. Curr Biol 21(1):25-33
Searle JS, et al.  (2011) Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage. PLoS Genet 7(7):e1002176
Kaochar S, et al.  (2010) Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 107(50):21605-10
Taschner M, et al.  (2010) A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae. Mol Cell Biol 30(2):436-46
Theis JF, et al.  (2010) The DNA Damage Response Pathway Contributes to the Stability of Chromosome III Derivatives Lacking Efficient Replicators. PLoS Genet 6(12):e1001227
Wood MD and Sanchez Y  (2010) Deregulated Ras signaling compromises DNA damage checkpoint recovery in S. cerevisiae. Cell Cycle 9(16):3353-63
Chen Y, et al.  (2009) ATRMec1 phosphorylation-independent activation of Chk1 in vivo. J Biol Chem 284(1):182-90
Heidinger-Pauli JM, et al.  (2009) Distinct targets of the Eco1 acetyltransferase modulate cohesion in S phase and in response to DNA damage. Mol Cell 34(3):311-21
Liang F, et al.  (2009) The molecular function of the yeast polo-like kinase Cdc5 in Cdc14 release during early anaphase. Mol Biol Cell 20(16):3671-9
Lin YH, et al.  (2009) Recruitment of rad51 and rad52 to short telomeres triggers a mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast. PLoS One 4(12):e8224
Pereira E, et al.  (2009) Conserved ATRMec1 phosphorylation-independent activation of Chk1 by single amino acid substitution in the GD domain. Cell Cycle 8(11):1788-93
Putnam CD, et al.  (2009) Specific pathways prevent duplication-mediated genome rearrangements. Nature 460(7258):984-9
Caldwell JM, et al.  (2008) Orchestration of the S-phase and DNA damage checkpoint pathways by replication forks from early origins. J Cell Biol 180(6):1073-86
Heidinger-Pauli JM, et al.  (2008) The kleisin subunit of cohesin dictates damage-induced cohesion. Mol Cell 31(1):47-56
Hwang JY, et al.  (2008) Smc5-Smc6 complex suppresses gross chromosomal rearrangements mediated by break-induced replications. DNA Repair (Amst) 7(9):1426-36
Kim EM and Burke DJ  (2008) DNA damage activates the SAC in an ATM/ATR-dependent manner, independently of the kinetochore. PLoS Genet 4(2):e1000015
Lee K, et al.  (2008) Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454(7203):543-6
McCue PP and Phang JM  (2008) Identification of Human Intracellular Targets of the Medicinal Herb St. John's Wort by Chemical-Genetic Profiling in Yeast. J Agric Food Chem 56(22):11011-11017
Morin I, et al.  (2008) Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response. EMBO J 27(18):2400-10
Razidlo DF and Lahue RS  (2008) Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms. DNA Repair (Amst) 7(4):633-40
Segurado M and Diffley JF  (2008) Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. Genes Dev 22(13):1816-27
Seitomer E, et al.  (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium. Mol Nutr Food Res 52(11):1305-15
Bracesco N, et al.  (2007) Roles of Saccharomyces cerevisiae RAD17 and CHK1 checkpoint genes in the repair of double-strand breaks in cycling cells. Radiat Environ Biophys 46(4):401-7
Dotiwala F, et al.  (2007) The yeast DNA damage checkpoint proteins control a cytoplasmic response to DNA damage. Proc Natl Acad Sci U S A 104(27):11358-63
Liang F and Wang Y  (2007) DNA damage checkpoints inhibit mitotic exit by two different mechanisms. Mol Cell Biol 27(14):5067-78