UBC4/YBR082C Literature Guide Help

Other names published for UBC4: E2 ubiquitin-conjugating protein UBC4, YBR082C

UBC4 - Mutants/Phenotypes (76)

ReferenceOther Genes Addressed
Kiktev DA, et al.  (2012) Regulation of chaperone effects on a yeast prion by cochaperone Sgt2. Mol Cell Biol 32(24):4960-70
Singh RK, et al.  (2012) Novel E3 Ubiquitin Ligases That Regulate Histone Protein Levels in the Budding Yeast Saccharomyces cerevisiae. PLoS One 7(5):e36295
Theodoraki MA, et al.  (2012) A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast. J Biol Chem 287(28):23911-22
Chernova TA, et al.  (2011) Prion induction by the short-lived, stress-induced protein lsb2 is regulated by ubiquitination and association with the actin cytoskeleton. Mol Cell 43(2):242-52
Fang NN, et al.  (2011) Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins. Nat Cell Biol 13(11):1344-52
Rabut G, et al.  (2011) The TFIIH Subunit Tfb3 Regulates Cullin Neddylation. Mol Cell 43(3):488-95
Stoll KE, et al.  (2011) The Essential Ubc4/Ubc5 Function in Yeast Is HECT E3-dependent, and RING E3-dependent Pathways Require Only Monoubiquitin Transfer by Ubc4. J Biol Chem 286(17):15165-70
Wang Y, et al.  (2011) Ubiquitin-dependent Proteasomal Degradation of Human Liver Cytochrome P450 2E1: IDENTIFICATION OF SITES TARGETED FOR PHOSPHORYLATION AND UBIQUITINATION. J Biol Chem 286(11):9443-56
Abelson J, et al.  (2010) Conformational dynamics of single pre-mRNA molecules during in vitro splicing. Nat Struct Mol Biol 17(4):504-12
Bhattacharya A, et al.  (2010) Why Dom34 Stimulates Growth of Cells with Defects of 40S Ribosomal Subunit Biosynthesis. Mol Cell Biol 30(23):5562-71
Das-Bradoo S, et al.  (2010) Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107. Nat Cell Biol 12(1):74-9; sup pp 1-20
Greenland KB, et al.  (2010) Identification of Saccharomyces cerevisiae Spindle Pole Body Remodeling Factors. PLoS One 5(11):e15426
Haworth J, et al.  (2010) Ubc4 and Not4 Regulate Steady-State Levels of DNA Polymerase-{alpha} to Promote Efficient and Accurate DNA Replication. Mol Biol Cell 21(18):3205-19
Heck JW, et al.  (2010) Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. Proc Natl Acad Sci U S A 107(3):1106-11
Kammerer D, et al.  (2010) Ubiquitylation Regulates Interactions of Astral Microtubules with the Cleavage Apparatus. Curr Biol 20(14):1233-1243
Mira NP, et al.  (2010) Genome-wide identification of Saccharomyces cerevisiae genes required for tolerance to acetic acid. Microb Cell Fact 9(1):79
Nillegoda NB, et al.  (2010) Ubr1 and ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell 21(13):2102-16
Nixon CE, et al.  (2010) Degradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathways. Genetics 185(2):497-511
Xie Y, et al.  (2010) SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor. Genes Dev 24(9):893-903
Hiraishi H, et al.  (2009) A functional analysis of the yeast ubiquitin ligase rsp5: the involvement of the ubiquitin-conjugating enzyme ubc4 and poly-ubiquitination in ethanol-induced down-regulation of targeted proteins. Biosci Biotechnol Biochem 73(10):2268-73
Lundh F, et al.  (2009) Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry 48(21):4497-505
Panasenko OO, et al.  (2009) Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination. Genetics 181(2):447-60
Postma L, et al.  (2009) Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive. Aging (Albany NY) 1(11):957-60
Singh RK, et al.  (2009) Histone levels are regulated by phosphorylation and ubiquitylation-dependent proteolysis. Nat Cell Biol 11(8):925-33
Wang Z and Prelich G  (2009) Quality control of a transcriptional regulator by SUMO-targeted degradation. Mol Cell Biol 29(7):1694-706
Duennwald ML and Lindquist S  (2008) Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 22(23):3308-3319
Hwang GW, et al.  (2008) The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms. Life Sci 82(23-24):1182-5
Kaganovich D, et al.  (2008) Misfolded proteins partition between two distinct quality control compartments. Nature 454(7208):1088-95
Loring GL, et al.  (2008) Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7(1):96-105
Metzger MB, et al.  (2008) Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery. J Biol Chem 283(47):32302-16