CHS2/YBR038W Literature Guide Help

Other names published for CHS2: chitin synthase CHS2, YBR038W

CHS2 - Mutants/Phenotypes (30)

ReferenceOther Genes Addressed
Chin CF, et al.  (2012) Dependence of Chs2 ER export on dephosphorylation by cytoplasmic Cdc14 ensures that septum formation follows mitosis. Mol Biol Cell 23(1):45-58
Oh Y, et al.  (2012) Mitotic exit kinase Dbf2 directly phosphorylates chitin synthase Chs2 to regulate cytokinesis in budding yeast. Mol Biol Cell 23(13):2445-56
Pagan-Mercado G, et al.  (2012) Functional and genetic interactions of TOR in the budding yeast Saccharomyces cerevisiae with myosin type II-deficiency (myo1Delta). BMC Cell Biol 13(1):13
Martinez-Rucobo FW, et al.  (2009) Yeast chitin synthase 2 activity is modulated by proteolysis and phosphorylation. Biochem J 417(2):547-54
Nishihama R, et al.  (2009) Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. J Cell Biol 185(6):995-1012
Rodriguez-Quinones JF and Rodriguez-Medina JR  (2009) Differential gene expression signatures for cell wall integrity found in chitin synthase II (chs2Delta) and myosin II (myo1Delta) deficient cytokinesis mutants of Saccharomyces cerevisiae. BMC Res Notes 2:87
Rolli E, et al.  (2009) Immobilization of the glycosylphosphatidylinositol-anchored Gas1 protein into the chitin ring and septum is required for proper morphogenesis in yeast. Mol Biol Cell 20(22):4856-70
Teh EM, et al.  (2009) Retention of Chs2p in the ER requires N-terminal CDK1-phosphorylation sites. Cell Cycle 8(18):2964-74
Breslow DK, et al.  (2008) A comprehensive strategy enabling high-resolution functional analysis of the yeast genome. Nat Methods 5(8):711-8
Bicknell AA, et al.  (2007) A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response. J Cell Biol 177(6):1017-27
Schmidt M, et al.  (2005) Importance of cell wall mannoproteins for septum formation in Saccharomyces cerevisiae. Yeast 22(9):715-23
Dobbelaere J and Barral Y  (2004) Spatial coordination of cytokinetic events by compartmentalization of the cell cortex. Science 305(5682):393-6
Matsuo Y, et al.  (2004) Genetic analysis of chs1+ and chs2+ encoding chitin synthases from Schizosaccharomyces pombe. Biosci Biotechnol Biochem 68(7):1489-99
Schmidt M  (2004) Survival and cytokinesis of Saccharomyces cerevisiae in the absence of chitin. Microbiology 150(Pt 10):3253-60
Selvaggini S, et al.  (2004) Independent regulation of chitin synthase and chitinase activity in Candida albicans and Saccharomyces cerevisiae. Microbiology 150(Pt 4):921-8
Cabib E and Schmidt M  (2003) Chitin synthase III activity, but not the chitin ring, is required for remedial septa formation in budding yeast. FEMS Microbiol Lett 224(2):299-305
Roh DH, et al.  (2002) The septation apparatus, an autonomous system in budding yeast. Mol Biol Cell 13(8):2747-59
Schmidt M, et al.  (2002) In budding yeast, contraction of the actomyosin ring and formation of the primary septum at cytokinesis depend on each other. J Cell Sci 115(Pt 2):293-302
Jablonowski D, et al.  (2001) Saccharomyces cerevisiae cell wall chitin, the Kluyveromyces lactis zymocin receptor. Yeast 18(14):1285-99
Sudoh M, et al.  (2000) Identification of a novel inhibitor specific to the fungal chitin synthase. Inhibition of chitin synthase 1 arrests the cell growth, but inhibition of chitin synthase 1 and 2 is lethal in the pathogenic fungus Candida albicans. J Biol Chem 275(42):32901-5
Martin H, et al.  (1999) KNR4, a suppressor of Saccharomyces cerevisiae cwh mutants, is involved in the transcriptional control of chitin synthase genes. Microbiology 145 ( Pt 1)():249-58
Cos T, et al.  (1998) Molecular analysis of Chs3p participation in chitin synthase III activity. Eur J Biochem 256(2):419-26
Yabe T, et al.  (1998) Mutational analysis of chitin synthase 2 of Saccharomyces cerevisiae. Identification of additional amino acid residues involved in its catalytic activity. Eur J Biochem 258(3):941-7
Ford RA, et al.  (1996) Yeast chitin synthases 1 and 2 consist of a non-homologous and dispensable N-terminal region and of a homologous moiety essential for function. Mol Gen Genet 252(4):420-8
Uchida Y, et al.  (1996) Characterization of chitin synthase 2 of Saccharomyces cerevisiae. II: Both full size and processed enzymes are active for chitin synthesis. J Biochem 119(4):659-66
Nagahashi S, et al.  (1995) Characterization of chitin synthase 2 of Saccharomyces cerevisiae. Implication of two highly conserved domains as possible catalytic sites. J Biol Chem 270(23):13961-7
Shaw JA, et al.  (1991) The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol 114(1):111-23
Bulawa CE and Osmond BC  (1990) Chitin synthase I and chitin synthase II are not required for chitin synthesis in vivo in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 87(19):7424-8
Cabib E, et al.  (1989) Chitin synthase 1, an auxiliary enzyme for chitin synthesis in Saccharomyces cerevisiae. J Cell Biol 108(5):1665-72
Silverman SJ, et al.  (1988) Chitin synthase 2 is essential for septum formation and cell division in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 85(13):4735-9