THO2/YNL139C Literature Guide Help

Other names published for THO2: ZRG13, LDB5, RLR1, YNL139C

THO2 - Genetic Interactions (13)

ReferenceOther Genes Addressed
Yu TY, et al.  (2012) Depleting Components of the THO Complex Causes Increased Telomere Length by Reducing the Expression of the Telomere-Associated Protein Rif1p. PLoS One 7(3):e33498
Bermejo R, et al.  (2011) The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
Skruzny M, et al.  (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8
Jimeno S, et al.  (2008) A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants. Mol Genet Genomics 280(4):327-36
Saguez C, et al.  (2008) Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation. Mol Cell 31(1):91-103
Jimeno S, et al.  (2006) Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants. Mol Cell Biol 26(12):4387-98
Rother S, et al.  (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25
Luna R, et al.  (2005) Interdependence between transcription and mRNP processing and export, and its impact on genetic stability. Mol Cell 18(6):711-22
Jimeno S, et al.  (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21(13):3526-35
Strasser K, et al.  (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417(6886):304-8
West RW Jr and Milgrom E  (2002) DEAD-box RNA helicase Sub2 is required for expression of lacZ fusions in Saccharomyces cerevisiae and is a dosage-dependent suppressor of RLR1 (THO2). Gene 288(1-2):19-27
West RW Jr, et al.  (2000) RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4. Gene 243(1-2):195-205
Piruat JI and Aguilera A  (1998) A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J 17(16):4859-72