SPT2/YER161C Literature Guide Help

Other names published for SPT2: SIN1, EXA1, YER161C

SPT2 - Genetic Interactions (25)

ReferenceOther Genes Addressed
Furukawa K, et al.  (2011) Efficient Construction of Homozygous Diploid Strains Identifies Genes Required for the Hyper-Filamentous Phenotype in Saccharomyces cerevisiae. PLoS One 6(10):e26584
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Zheng J, et al.  (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Imbeault D, et al.  (2008) The rtt106 histone chaperone is functionally linked to transcription elongation and is involved in the regulation of spurious transcription from cryptic promoters in yeast. J Biol Chem 283(41):27350-4
Sikdar N, et al.  (2008) Spt2p Defines a New Transcription-Dependent Gross Chromosomal Rearrangement Pathway. PLoS Genet 4(12):e1000290
Dobi KC and Winston F  (2007) Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae. Mol Cell Biol 27(15):5575-86
Hershkovits G, et al.  (2006) Recruitment of mRNA cleavage/polyadenylation machinery by the yeast chromatin protein Sin1p/Spt2p. Proc Natl Acad Sci U S A 103(26):9808-13
Nourani A, et al.  (2006) Evidence that Spt2/Sin1, an HMG-like factor, plays roles in transcription elongation, chromatin structure, and genome stability in Saccharomyces cerevisiae. Mol Cell Biol 26(4):1496-509
Novoseler M, et al.  (2005) Functional domains of the yeast chromatin protein Sin1p/Spt2p can bind four-way junction and crossing DNA structures. J Biol Chem 280(7):5169-77
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Yu Y, et al.  (2000) Architectural transcription factors and the SAGA complex function in parallel pathways to activate transcription. Mol Cell Biol 20(7):2350-7
Baxter BK and Craig EA  (1998) Suppression of an Hsp70 mutant phenotype in Saccharomyces cerevisiae through loss of function of the chromatin component Sin1p/Spt2p. J Bacteriol 180(24):6484-92
Perez-Martin J and Johnson AD  (1998) Mutations in chromatin components suppress a defect of Gcn5 protein in Saccharomyces cerevisiae. Mol Cell Biol 18(2):1049-54
Perez-Martin J and Johnson AD  (1998) The C-terminal domain of Sin1 interacts with the SWI-SNF complex in yeast. Mol Cell Biol 18(7):4157-64
Pollard KJ and Peterson CL  (1997) Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression. Mol Cell Biol 17(11):6212-22
Zhu Y, et al.  (1995) HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae. Mol Cell Biol 15(3):1698-708
Katcoff DJ, et al.  (1993) SIN1 interacts with a protein that binds the URS1 region of the yeast HO gene. Nucleic Acids Res 21(22):5101-9
Lefebvre L and Smith M  (1993) Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae. Mol Cell Biol 13(9):5393-407
Longtine MS, et al.  (1993) Telomere-mediated plasmid segregation in Saccharomyces cerevisiae involves gene products required for transcriptional repression at silencers and telomeres. Genetics 133(2):171-82
Nelson RJ, et al.  (1992) Isolation and characterization of extragenic suppressors of mutations in the SSA hsp70 genes of Saccharomyces cerevisiae. Genetics 131(2):277-85
Kruger W and Herskowitz I  (1991) A negative regulator of HO transcription, SIN1 (SPT2), is a nonspecific DNA-binding protein related to HMG1. Mol Cell Biol 11(8):4135-46
Peterson CL, et al.  (1991) A functional interaction between the C-terminal domain of RNA polymerase II and the negative regulator SIN1. Cell 64(6):1135-43
Roeder GS, et al.  (1985) Isolation and characterization of the SPT2 gene, a negative regulator of Ty-controlled yeast gene expression. Mol Cell Biol 5(7):1543-53
Simchen G, et al.  (1984) Ty-mediated gene expression of the LYS2 and HIS4 genes of Saccharomyces cerevisiae is controlled by the same SPT genes. Proc Natl Acad Sci U S A 81(8):2431-4
Winston F, et al.  (1984) Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae. Genetics 107(2):179-97