Other names published for SIR4: ASD1, STE9, UTH2, YDR227W
SIR4 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cell Cycle Phase Involved
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
SIR4 - Genetic Interactions (79)
| Reference | Other Genes Addressed |
|---|---|
| Kueng S, et al. (2012) Regulating repression: roles for the sir4 N-terminus in linker DNA protection and stabilization of epigenetic States. PLoS Genet 8(5):e1002727 | |
| Nagesh P, et al. (2012) The SUMO E3 ligase Siz2 exerts a locus-dependent effect on gene silencing in Saccharomyces cerevisiae. Eukaryot Cell 11(4):452-62 | |
| Chen C, et al. (2011) Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification. PLoS Genet 7(9):e1002258 | |
| Iglesias N, et al. (2011) Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep 12(6):587-93 | |
| Leung A, et al. (2011) Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat. Mol Biol Cell 22(15):2741-53 | |
| Wang CY, et al. (2011) The C-Terminus of Histone H2B Is Involved in Chromatin Compaction Specifically at Telomeres, Independently of Its Monoubiquitylation at Lysine 123. PLoS One 6(7):e22209 | |
| Wu CS, et al. (2011) Targeted sister chromatid cohesion by sir2. PLoS Genet 7(2):e1002000 | |
| Ehrentraut S, et al. (2010) Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. Proc Natl Acad Sci U S A 107(12):5522-7 | |
| Kozak ML, et al. (2010) Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J 29(1):158-70 | |
| Toussaint M, et al. (2010) Differential participation of homologous recombination and nucleotide excision repair in yeast survival to ultraviolet light radiation. Mutat Res 698(1-2):52-59 | |
| Yu Q, et al. (2010) Saccharomyces cerevisiae Esc2p Interacts with Sir2p through a Small Ubiquitin-like Modifier (SUMO)-binding Motif and Regulates Transcriptionally Silent Chromatin in a Locus-dependent Manner. J Biol Chem 285(10):7525-36 | |
| Bystricky K, et al. (2009) Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol 29(3):835-48 | |
| Fung CW, et al. (2009) Suppression of the Double-Strand-Break-Repair Defect of the Saccharomyces cerevisiae rad57 Mutant. Genetics 181(4):1195-206 | |
| Wasko BM, et al. (2009) Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. DNA Repair (Amst) 8(2):162-9 | |
| Choi JK, et al. (2008) Stochastic and regulatory role of chromatin silencing in genomic response to environmental changes. PLoS ONE 3(8):e3002 | |
| Darst RP, et al. (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72 | |
| Greenall A, et al. (2008) A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome Biol 9(10):R146 | |
| Marcand S, et al. (2008) Multiple pathways inhibit NHEJ at telomeres. Genes Dev 22(9):1153-8 | |
| Mozlin AM, et al. (2008) Role of the Saccharomyces cerevisiae Rad51 Paralogs in Sister Chromatid Recombination. Genetics 178(1):113-26 | |
| Yang B, et al. (2008) Insights into the impact of histone acetylation and methylation on Sir protein recruitment, spreading, and silencing in Saccharomyces cerevisiae. J Mol Biol 381(4):826-44 | |
| Jin Y, et al. (2007) Simultaneous Mutation of Methylated Lysine Residues in Histone H3 Causes Enhanced Gene Silencing, Cell Cycle Defects, and Cell Lethality in Saccharomyces cerevisiae. Mol Cell Biol 27(19):6832-41 | |
| Lewis A, et al. (2007) A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance. J Cell Biol 178(5):813-27 | |
| Nishida Y and Ono B (2007) An experimental system for the study of mutations in the HMR locus of Saccharomyces cerevisiae: the insertion of Ty into HMRa vs. the conversion of HMRa to HMRalpha. Yeast 24(9):723-30 | |
| Venkatasubrahmanyam S, et al. (2007) Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z. Proc Natl Acad Sci U S A 104(42):16609-14 | |
| Clement M, et al. (2006) The nuclear GTPase Gsp1p can affect proper telomeric function through the Sir4 protein in Saccharomyces cerevisiae. Mol Microbiol 62(2):453-468 | |
| Hediger F, et al. (2006) Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. EMBO J 25(4):857-67 | |
| Hiraga SI, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 | |
| McCullock S, et al. (2006) blm3-1 Is an Allele of UBP3, a Ubiquitin Protease that Appears to Act During Transcription of Damaged DNA. J Mol Biol 363(3):660-72 | |
| Ohkuni K, et al. (2006) Suppressor analysis of the mpt5/htr1/uth4/puf5 deletion in Saccharomyces cerevisiae. Mol Genet Genomics 275(1):81-8 | |
| Yang B and Kirchmaier AL (2006) Bypassing the Catalytic Activity of SIR2 for SIR Protein Spreading in Saccharomyces cerevisiae. Mol Biol Cell 17(12):5287-97 |



