Other names published for SIR4: ASD1, STE9, UTH2, YDR227W
SIR4 LITERATURE TOPICS
- Genetics/Cell Biology
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Curated Literature
- Additional Information
SIR4 - Genetic Interactions (70)
| Reference | Other Genes Addressed |
|---|---|
| Ehrentraut S, et al. (2010) Rpd3-dependent boundary formation at telomeres by removal of Sir2 substrate. Proc Natl Acad Sci U S A () | |
| Kozak ML, et al. (2010) Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. EMBO J 29(1):158-70 | |
| Yu Q, et al. (2010) Saccharomyces cerevisiae Esc2p interacts with Sir2p through a SUMO-binding motif and regulates transcriptionally silent chromatin in a locus-dependent manner. J Biol Chem () | |
| Bystricky K, et al. (2009) Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Mol Cell Biol 29(3):835-48 | |
| Fung CW, et al. (2009) Suppression of the Double-Strand-Break-Repair Defect of the Saccharomyces cerevisiae rad57 Mutant. Genetics 181(4):1195-206 | |
| Wasko BM, et al. (2009) Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae. DNA Repair (Amst) 8(2):162-9 | |
| Choi JK, et al. (2008) Stochastic and regulatory role of chromatin silencing in genomic response to environmental changes. PLoS ONE 3(8):e3002 | |
| Darst RP, et al. (2008) Slx5 promotes transcriptional silencing and is required for robust growth in the absence of Sir2. Mol Cell Biol 28(4):1361-72 | |
| Greenall A, et al. (2008) A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection. Genome Biol 9(10):R146 | |
| Marcand S, et al. (2008) Multiple pathways inhibit NHEJ at telomeres. Genes Dev 22(9):1153-8 | |
| Mozlin AM, et al. (2008) Role of the Saccharomyces cerevisiae Rad51 Paralogs in Sister Chromatid Recombination. Genetics 178(1):113-26 | |
| Yang B, et al. (2008) Insights into the impact of histone acetylation and methylation on Sir protein recruitment, spreading, and silencing in Saccharomyces cerevisiae. J Mol Biol 381(4):826-44 | |
| Jin Y, et al. (2007) Simultaneous Mutation of Methylated Lysine Residues in Histone H3 Causes Enhanced Gene Silencing, Cell Cycle Defects, and Cell Lethality in Saccharomyces cerevisiae. Mol Cell Biol 27(19):6832-41 | |
| Lewis A, et al. (2007) A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance. J Cell Biol 178(5):813-27 | |
| Nishida Y and Ono B (2007) An experimental system for the study of mutations in the HMR locus of Saccharomyces cerevisiae: the insertion of Ty into HMRa vs. the conversion of HMRa to HMRalpha. Yeast 24(9):723-30 | |
| Venkatasubrahmanyam S, et al. (2007) Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z. Proc Natl Acad Sci U S A 104(42):16609-14 | |
| Clement M, et al. (2006) The nuclear GTPase Gsp1p can affect proper telomeric function through the Sir4 protein in Saccharomyces cerevisiae. Mol Microbiol 62(2):453-468 | |
| Hediger F, et al. (2006) Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. EMBO J 25(4):857-67 | |
| Hiraga S, et al. (2006) The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time. EMBO J 25(7):1505-14 | |
| McCullock S, et al. (2006) blm3-1 Is an Allele of UBP3, a Ubiquitin Protease that Appears to Act During Transcription of Damaged DNA. J Mol Biol 363(3):660-72 | |
| Ohkuni K, et al. (2006) Suppressor analysis of the mpt5/htr1/uth4/puf5 deletion in Saccharomyces cerevisiae. Mol Genet Genomics 275(1):81-8 | |
| Yang B and Kirchmaier AL (2006) Bypassing the Catalytic Activity of SIR2 for SIR Protein Spreading in Saccharomyces cerevisiae. Mol Biol Cell 17(12):5287-97 | |
| Daniel J (2005) Sir-dependent downregulation of various aging processes. Mol Genet Genomics 274(5):539-47 | |
| Das SP and Sinha P (2005) The budding yeast protein Chl1p has a role in transcriptional silencing, rDNA recombination, and aging. Biochem Biophys Res Commun 337(1):167-72 | |
| Nishida Y, et al. (2004) Mating-induced mating-type cassette conversion in Saccharomyces cerevisiae. Yeast 21(13):1095-105 | |
| Orlandi I, et al. (2004) Transcriptional profiling of ubp10 null mutant reveals altered subtelomeric gene expression and insurgence of oxidative stress response. J Biol Chem 279(8):6414-25 | |
| Pappas DL Jr, et al. (2004) The NAD(+)-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication. Genes Dev 18(7):769-81 | |
| Radford SJ, et al. (2004) Increase in Ty1 cDNA recombination in yeast sir4 mutant strains at high temperature. Genetics 168(1):89-101 | |
| Fuerst PG and Voytas DF (2003) CEN plasmid segregation is destabilized by tethered determinants of Ty 5 integration specificity: a role for double-strand breaks in CEN antagonism. Chromosoma 112(2):58-65 | |
| Lewis LK, et al. (2002) Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). Genetics 160(1):49-62 |






