RAT1/YOR048C Literature Guide Help

Other names published for RAT1: HKE1, TAP1, XRN2, YOR048C

RAT1 - Genetic Interactions (22)

ReferenceOther Genes Addressed
Egecioglu DE, et al.  (2012) Quality control of MATa1 splicing and exon skipping by nuclear RNA degradation. Nucleic Acids Res 40(4):1787-96
Sinturel F, et al.  (2012) Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast. Proc Natl Acad Sci U S A 109(21):8264-9
Iglesias N, et al.  (2011) Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep 12(6):587-93
Jimeno-Gonzalez S, et al.  (2010) The Yeast 5'-3' Exonuclease Rat1p Functions during Transcription Elongation by RNA Polymerase II. Mol Cell 37(4):580-587
Ghazal G, et al.  (2009) Yeast RNase III triggers polyadenylation-independent transcription termination. Mol Cell 36(1):99-109
Oeffinger M, et al.  (2009) Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA. Mol Cell 36(5):768-81
Rondon AG, et al.  (2009) Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae. Mol Cell 36(1):88-98
Chernyakov I, et al.  (2008) Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. Genes Dev 22(10):1369-80
El Hage A, et al.  (2008) Efficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeast. Genes Dev 22(8):1069-81
Gonzalez-Aguilera C, et al.  (2008) The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability. Mol Biol Cell 19(10):4310-8
Kawauchi J, et al.  (2008) Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination. Genes Dev 22(8):1082-92
Luke B, et al.  (2008) The Rat1p 5' to 3' Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae. Mol Cell 32(4):465-77
Luo W, et al.  (2006) The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model. Genes Dev 20(8):954-65
Fang F, et al.  (2005) Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors. RNA 11(10):1571-8
Lee A, et al.  (2005) Multiple RNA surveillance pathways limit aberrant expression of iron uptake mRNAs and prevent iron toxicity in S. cerevisiae. Mol Cell 19(1):39-51
Lee CY, et al.  (2003) The roles of endonucleolytic cleavage and exonucleolytic digestion in the 5'-end processing of S. cerevisiae box C/D snoRNAs. RNA 9(11):1362-70
Bousquet-Antonelli C, et al.  (2000) Identification of a regulated pathway for nuclear pre-mRNA turnover. Cell 102(6):765-75
Geerlings TH, et al.  (2000) The final step in the formation of 25S rRNA in Saccharomyces cerevisiae is performed by 5'-->3' exonucleases. RNA 6(12):1698-703
Xue Y, et al.  (2000) Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. Mol Cell Biol 20(11):4006-15
Dichtl B, et al.  (1997) Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J 16(23):7184-95
Johnson AW  (1997) Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively. Mol Cell Biol 17(10):6122-30
Poole TL and Stevens A  (1995) Comparison of features of the RNase activity of 5'-exonuclease-1 and 5'-exonuclease-2 of Saccharomyces cerevisiae. Nucleic Acids Symp Ser (33):79-81