NTG2/YOL043C Literature Guide Help

Other names published for NTG2: SCR2, bifunctional N-glycosylase/AP lyase NTG2, YOL043C

NTG2 - Genetic Interactions (38)

ReferenceOther Genes Addressed
Collura A, et al.  (2012) Abasic sites linked to dUTP incorporation in DNA are a major cause of spontaneous mutations in absence of base excision repair and Rad17-Mec3-Ddc1 (9-1-1) DNA damage checkpoint clamp in Saccharomyces cerevisiae. DNA Repair (Amst) 11(3):294-303
Morris LP, et al.  (2012) Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. DNA Repair (Amst) 11(9):753-65
Reis AM, et al.  (2012) Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand. Nucleic Acids Res 40(1):206-19
Sobol Z and Schiestl RH  (2012) Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen 53(2):94-100
Kim N, et al.  (2011) The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites. DNA Repair (Amst) 10(12):1262-71
Ma W, et al.  (2011) Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease. PLoS Genet 7(4):e1002059
Reid RJ, et al.  (2011) Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage. Genome Res 21(3):477-86
Daley JM, et al.  (2010) Genetic interactions between HNT3/Aprataxin and RAD27/FEN1 suggest parallel pathways for 5' end processing during base excision repair. DNA Repair (Amst) 9(6):690-9
Degrandi TH, et al.  (2010) Evaluation of the cytotoxicity, genotoxicity and mutagenicity of diphenyl ditelluride in several biological models. Mutagenesis 25(3):257-69
Kim N and Jinks-Robertson S  (2010) Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair. Mol Cell Biol 30(13):3206-15
Manikova D, et al.  (2010) Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae. Mutagenesis 25(2):155-62
Matuo R, et al.  (2010) DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP. Biochem Pharmacol 79(2):147-53
Northam MR, et al.  (2010) Participation of DNA polymerase {zeta} in replication of undamaged DNA in Saccharomyces cerevisiae. Genetics 184(1):27-42
Serrentino ME, et al.  (2010) Photosensitization induced by the antibacterial fluoroquinolone Rufloxacin leads to mutagenesis in yeast. Mutat Res 692(1-2):34-41
Steininger S, et al.  (2010) A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair. Nucleic Acids Res 38(6):1853-65
Swartzlander DB, et al.  (2010) Regulation of base excision repair: Ntg1 nuclear and mitochondrial dynamic localization in response to genotoxic stress. Nucleic Acids Res 38(12):3963-74
Kim N and Jinks-Robertson S  (2009) dUTP incorporation into genomic DNA is linked to transcription in yeast. Nature 459(7250):1150-3
Degtyareva NP, et al.  (2008) Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol 28(17):5432-45
Gellon L, et al.  (2008) Intrinsic 5'-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair (Amst) 7(2):187-98
Serero A, et al.  (2008) Yeast genes involved in cadmium tolerance: Identification of DNA replication as a target of cadmium toxicity. DNA Repair (Amst) 7(8):1262-75
Allen BG, et al.  (2006) Base excision repair of both uracil and oxidatively damaged bases contribute to thymidine deprivation-induced radiosensitization. Int J Radiat Oncol Biol Phys 65(5):1544-52
Seiple L, et al.  (2006) Linking uracil base excision repair and 5-fluorouracil toxicity in yeast. Nucleic Acids Res 34(1):140-51
Viau C, et al.  (2006) Sensitivity to Sn(2+) of the Yeast Saccharomyces cerevisiae Depends on General Energy Metabolism, Metal Transport, Anti-Oxidative Defences, and DNA Repair. Biometals 19(6):705-14
Dornfeld K and Johnson M  (2005) AP endonuclease deficiency results in extreme sensitivity to thymidine deprivation. Nucleic Acids Res 33(20):6644-53
Soares DG, et al.  (2005) Low cytotoxicity of ecteinascidin 743 in yeast lacking the major endonucleolytic enzymes of base and nucleotide excision repair pathways. Biochem Pharmacol 70(1):59-69
Beljanski V, et al.  (2004) DNA damage-processing pathways involved in the eukaryotic cellular response to anticancer DNA cross-linking drugs. Mol Pharmacol 65(6):1496-506
Hanna M, et al.  (2004) Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. DNA Repair (Amst) 3(1):51-9
Melo RG, et al.  (2004) Role of OGG1 and NTG2 in the repair of oxidative DNA damage and mutagenesis induced by hydrogen peroxide in Saccharomyces cerevisiae: relationships with transition metals iron and copper. Yeast 21(12):991-1003
Salmon TB, et al.  (2004) Biological consequences of oxidative stress-induced DNA damage in Saccharomyces cerevisiae. Nucleic Acids Res 32(12):3712-23
Guillet M and Boiteux S  (2003) Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol Cell Biol 23(22):8386-94