IRA1/YBR140C Literature Guide Help

Other names published for IRA1: GLC1, PPD1, YBR140C

IRA1 - Genetic Interactions (29)

ReferenceOther Genes Addressed
Barrett L, et al.  (2012) Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae. Eukaryot Cell 11(2):119-28
Darby MM, et al.  (2012) The Saccharomyces cerevisiae Nrd1-Nab3 transcription termination pathway acts in opposition to Ras signaling and mediates response to nutrient depletion. Mol Cell Biol 32(10):1762-75
Wood MD and Sanchez Y  (2010) Deregulated Ras signaling compromises DNA damage checkpoint recovery in S. cerevisiae. Cell Cycle 9(16):3353-63
Bishop AC, et al.  (2009) Neurofibromin homologs Ira1 and Ira2 affect glycerophosphoinositol production and transport in Saccharomyces cerevisiae. Eukaryot Cell 8(11):1808-11
Belotti F, et al.  (2006) The N-terminal region of the Saccharomyces cerevisiae RasGEF Cdc25 is required for nutrient-dependent cell-size regulation. Microbiology 152(Pt 4):1231-42
Harashima T, et al.  (2006) The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2. Mol Cell 22(6):819-30
Trott A, et al.  (2005) The molecular chaperone Sse1 and the growth control protein kinase Sch9 collaborate to regulate protein kinase A activity in Saccharomyces cerevisiae. Genetics 170(3):1009-21
Zurita-Martinez SA and Cardenas ME  (2005) Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth. Eukaryot Cell 4(1):63-71
Chautard H, et al.  (2004) Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae. Eukaryot Cell 3(2):459-70
Colombo S, et al.  (2004) Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. J Biol Chem 279(45):46715-22
Enjalbert B, et al.  (2004) Combinatorial control by the protein kinases PKA, PHO85 and SNF1 of transcriptional induction of the Saccharomyces cerevisiae GSY2 gene at the diauxic shift. Mol Genet Genomics 271(6):697-708
Dejean L, et al.  (2002) Activation of Ras cascade increases the mitochondrial enzyme content of respiratory competent yeast. Biochem Biophys Res Commun 293(5):1383-8
Scherz R, et al.  (2001) Anatomical analysis of Saccharomyces cerevisiae stalk-like structures reveals spatial organization and cell specialization. J Bacteriol 183(18):5402-13
Chen RA, et al.  (2000) A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics 154(4):1473-84
Zhu X, et al.  (2000) MSI1 suppresses hyperactive RAS via the cAMP-dependent protein kinase and independently of chromatin assembly factor-1. Curr Genet 38(2):60-70
Colombo S, et al.  (1998) Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae. EMBO J 17(12):3326-41
Fujimura K, et al.  (1994) The Saccharomyces cerevisiae MSI4 gene encodes the yeast counterpart of component A of Rab geranylgeranyltransferase. J Biol Chem 269(12):9205-12
Shirayama M, et al.  (1994) Isolation of a CDC25 family gene, MSI2/LTE1, as a multicopy suppressor of ira1. Yeast 10(4):451-61
Matviw H, et al.  (1993) The Schizosaccharomyces pombe pde1/cgs2 gene encodes a cyclic AMP phosphodiesterase. Biochem Biophys Res Commun 194(1):79-82
Qian YW, et al.  (1993) A retinoblastoma-binding protein related to a negative regulator of Ras in yeast. Nature 364(6438):648-52
Shirayama M, et al.  (1993) MSI3, a multicopy suppressor of mutants hyperactivated in the RAS-cAMP pathway, encodes a novel HSP70 protein of Saccharomyces cerevisiae. Mol Gen Genet 240(3):323-32
Kim JH and Powers S  (1991) Overexpression of RPI1, a novel inhibitor of the yeast Ras-cyclic AMP pathway, down-regulates normal but not mutationally activated ras function. Mol Cell Biol 11(8):3894-904
Tanaka K, et al.  (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13
Xu GF, et al.  (1990) The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae. Cell 63(4):835-41
Ballester R, et al.  (1989) Genetic analysis of mammalian GAP expressed in yeast. Cell 59(4):681-6
Ruggieri R, et al.  (1989) MSI1, a negative regulator of the RAS-cAMP pathway in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 86(22):8778-82
Tanaka K, et al.  (1989) IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae. Mol Cell Biol 9(2):757-68
Matsumoto K, et al.  (1985) Isolation and characterization of a phosphoprotein phosphatase-deficient mutant in yeast. Yeast 1(1):25-38
Padrao GR, et al.  (1982) Regulation of energy metabolism in yeast. Inheritance of a pleiotropic mutation causing defects in metabolism of energy reserves, ethanol utilization and formation of cytochrome a.a3. Mol Gen Genet 185(2):255-61