HPR1/YDR138W Literature Guide Help

Other names published for HPR1: TRF1, YDR138W

HPR1 - Genetic Interactions (45)

ReferenceOther Genes Addressed
Castellano-Pozo M, et al.  (2012) R-loops cause replication impairment and genome instability during meiosis. EMBO Rep 13(10):923-9
Yu TY, et al.  (2012) Depleting Components of the THO Complex Causes Increased Telomere Length by Reducing the Expression of the Telomere-Associated Protein Rif1p. PLoS One 7(3):e33498
Bermejo R, et al.  (2011) The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 146(2):233-46
Chanarat S, et al.  (2011) The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes. Genes Dev 25(11):1147-58
Jimeno S, et al.  (2011) New Suppressors of THO Mutations Identify Thp3 (Ypr045c)-Csn12 as a Protein Complex Involved in Transcription Elongation. Mol Cell Biol 31(4):674-685
Gomez-Gonzalez B, et al.  (2009) The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants. Mol Cell Biol 29(19):5203-13
Skruzny M, et al.  (2009) An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. PLoS Biol 7(1):e8
Grund SE, et al.  (2008) The inner nuclear membrane protein Src1 associates with subtelomeric genes and alters their regulated gene expression. J Cell Biol 182(5):897-910
Jimeno S, et al.  (2008) A reduction in RNA polymerase II initiation rate suppresses hyper-recombination and transcription-elongation impairment of THO mutants. Mol Genet Genomics 280(4):327-36
Seol JH, et al.  (2008) Analysis of Saccharomyces cerevisiae histone H3 mutants reveals the role of the alphaN helix in nucleosome function. Biochem Biophys Res Commun 374(3):543-8
Sikdar N, et al.  (2008) Spt2p Defines a New Transcription-Dependent Gross Chromosomal Rearrangement Pathway. PLoS Genet 4(12):e1000290
Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
Camblong J, et al.  (2007) Antisense RNA Stabilization Induces Transcriptional Gene Silencing via Histone Deacetylation in S. cerevisiae. Cell 131(4):706-17
Gaillard H, et al.  (2007) A new connection of mRNP biogenesis and export with transcription-coupled repair. Nucleic Acids Res 35(12):3893-906
Rougemaille M, et al.  (2007) Dissecting mechanisms of nuclear mRNA surveillance in THO/sub2 complex mutants. EMBO J 26(9):2317-26
Gwizdek C, et al.  (2006) Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription. Proc Natl Acad Sci U S A 103(44):16376-81
Huertas P, et al.  (2006) An hpr1 point mutation that impairs transcription and mRNP biogenesis without increasing recombination. Mol Cell Biol 26(20):7451-65
Jimeno S, et al.  (2006) Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants. Mol Cell Biol 26(12):4387-98
Preker PJ and Guthrie C  (2006) Autoregulation of the mRNA export factor Yra1p requires inefficient splicing of its pre-mRNA. RNA 12(6):994-1006
Rother S, et al.  (2006) Swt1, a novel yeast protein, functions in transcription. J Biol Chem 281(48):36518-25
Kus B, et al.  (2005) A high throughput screen to identify substrates for the ubiquitin ligase Rsp5. J Biol Chem 280(33):29470-8
Huertas P and Aguilera A  (2003) Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol Cell 12(3):711-21
Betz JL, et al.  (2002) Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics 268(2):272-85
Jimeno S, et al.  (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21(13):3526-35
Libri D, et al.  (2002) Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation. Mol Cell Biol 22(23):8254-66
Merker RJ and Klein HL  (2002) Role of transcription in plasmid maintenance in the hpr1Delta mutant of Saccharomyces cerevisiae. Mol Cell Biol 22(24):8763-73
Merker RJ and Klein HL  (2002) hpr1Delta affects ribosomal DNA recombination and cell life span in Saccharomyces cerevisiae. Mol Cell Biol 22(2):421-9
Strasser K, et al.  (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417(6886):304-8
Fan HY, et al.  (2001) High-copy-number expression of Sub2p, a member of the RNA helicase superfamily, suppresses hpr1-mediated genomic instability. Mol Cell Biol 21(16):5459-70
Gallardo M and Aguilera A  (2001) A new hyperrecombination mutation identifies a novel yeast gene, THP1, connecting transcription elongation with mitotic recombination. Genetics 157(1):79-89