GCN2/YDR283C Literature Guide Help

Other names published for GCN2: AAS1, NDR2, AAS102, YDR283C

GCN2 - Genetic Interactions (53)

Results: 1 - 30 of 53 records
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ReferenceOther Genes Addressed
Reid PJ, et al.  (2012) Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation. J Biol Chem 287(11):8275-85
Rodriguez-Hernandez CJ, et al.  (2012) Anti-diabetic and anti-obesity agent sodium tungstate enhances GCN pathway activation through Glc7p inhibition. FEBS Lett 586(3):270-6
Visweswaraiah J, et al.  (2012) Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation. J Biol Chem 287(45):37757-68
Iglesias-Gato D, et al.  (2011) Guanine Nucleotide Pool Imbalance Impairs Multiple Steps of Protein Synthesis and Disrupts GCN4 Translational Control in Saccharomyces cerevisiae. Genetics 187(1):105-22
Molin M, et al.  (2011) Life Span Extension and H(2)O(2) Resistance Elicited by Caloric Restriction Require the Peroxiredoxin Tsa1 in Saccharomyces cerevisiae. Mol Cell 43(5):823-33
Cherkasova V, et al.  (2010) Snf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4. Mol Cell Biol 30(12):2862-73
Ecker N, et al.  (2010) Induction of autophagic flux by amino acid deprivation is distinct from nitrogen starvation-induced macroautophagy. Autophagy 6(7):879-90
Elantak L, et al.  (2010) The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection. J Mol Biol 396(4):1097-1116
Jennings MD and Pavitt GD  (2010) eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 465(7296):378-81
Lin CA, et al.  (2010) The sua5 protein is essential for normal translational regulation in yeast. Mol Cell Biol 30(1):354-63
Rivera-Ruiz ME, et al.  (2010) Post-transcriptional regulation in the myo1Delta mutant of Saccharomyces cerevisiae. BMC Genomics 11():690
Staschke KA, et al.  (2010) Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast. J Biol Chem 285(22):16893-911
Deplazes A, et al.  (2009) Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J 28(10):1429-41
Fiedler D, et al.  (2009) Functional organization of the S. cerevisiae phosphorylation network. Cell 136(5):952-63
Garriz A, et al.  (2009) A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2. Mol Cell Biol 29(6):1592-607
Motlekar N, et al.  (2009) Discovery of Chemical Modulators of a Conserved Translational Control Pathway by Parallel Screening in Yeast. Assay Drug Dev Technol 7(5):479-494
Wout PK, et al.  (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71
Mascarenhas C, et al.  (2008) Gcn4 Is Required for the Response to Peroxide Stress in the Yeast Saccharomyces cerevisiae. Mol Biol Cell 19(7):2995-3007
Shirra MK, et al.  (2008) A Chemical Genomics Study Identifies Snf1 as a Repressor of GCN4 Translation. J Biol Chem 283(51):35889-98
Wang X, et al.  (2008) Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p. RNA 14(1):107-16
Cheung YN, et al.  (2007) Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo. Genes Dev 21(10):1217-30
Martin-Marcos P, et al.  (2007) Ribosomal protein L33 is required for ribosome biogenesis, subunit joining, and repression of GCN4 translation. Mol Cell Biol 27(17):5968-85
Conesa C, et al.  (2005) Modulation of yeast genome expression in response to defective RNA polymerase III-dependent transcription. Mol Cell Biol 25(19):8631-42
Gu W, et al.  (2005) Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C. Mol Cell Biol 25(18):8191-201
Magazinnik T, et al.  (2005) Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast. Nucleic Acids Res 33(14):4584-92
Nielsen KH, et al.  (2004) Functions of eIF3 downstream of 48S assembly impact AUG recognition and GCN4 translational control. EMBO J 23(5):1166-77
Richardson JP, et al.  (2004) Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity. Mol Cell Biol 24(6):2352-63
Sattlegger E, et al.  (2004) YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed. J Biol Chem 279(29):29952-62
Valasek L, et al.  (2004) Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selection. Mol Cell Biol 24(21):9437-55
Sattlegger E and Hinnebusch AG  (2000) Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells. EMBO J 19(23):6622-33
Results: 1 - 30 of 53 records
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