ERG5/YMR015C Literature Guide Help

Other names published for ERG5: CYP61, C-22 sterol desaturase, YMR015C

ERG5 - Genetic Interactions (12)

ReferenceOther Genes Addressed
Souza CM, et al.  (2011) A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance. Metab Eng 13(5):555-69
Aguilar PS, et al.  (2010) Structure of sterol aliphatic chains affects yeast cell shape and cell fusion during mating. Proc Natl Acad Sci U S A 107(9):4170-5
Hodg CA, et al.  (2010) Integral membrane proteins Brr6 and Apq12 link assembly of the nuclear pore complex to lipid homeostasis in the endoplasmic reticulum. J Cell Sci 123(Pt 1):141-151
Zhao J, et al.  (2010) The protein kinase Hal5p is the high-copy suppressor of lithium-sensitive mutations of genes involved in the sporulation and meiosis as well as the ergosterol biosynthesis in Saccharomyces cerevisiae. Genomics 95(5):290-8
Guan XL, et al.  (2009) Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology. Mol Biol Cell 20(7):2083-95
Wei M, et al.  (2009) Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 5(5):e1000467
Welscher YM, et al.  (2008) Natamycin Blocks Fungal Growth by Binding Specifically to Ergosterol without Permeabilizing the Membrane. J Biol Chem 283(10):6393-401
Valachovic M, et al.  (2006) Cumulative mutations affecting sterol biosynthesis in the yeast Saccharomyces cerevisiae result in synthetic lethality that is suppressed by alterations in sphingolipid profiles. Genetics 173(4):1893-908
Kishimoto T, et al.  (2005) Defects in structural integrity of ergosterol and the Cdc50p-Drs2p putative phospholipid translocase cause accumulation of endocytic membranes, onto which actin patches are assembled in yeast. Mol Biol Cell 16(12):5592-609
Heese-Peck A, et al.  (2002) Multiple functions of sterols in yeast endocytosis. Mol Biol Cell 13(8):2664-80
Venkateswarlu K, et al.  (1998) NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrob Agents Chemother 42(7):1756-61
Bard M, et al.  (1977) Sterol mutants of Saccharomyces cerevisiae: chromatographic analyses. Lipids 12(8):645-54