ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Genetic Interactions (14)

ReferenceOther Genes Addressed
Paluszynski JP, et al.  (2008) Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast. Microbiology 154(Pt 10):3154-64
Wu TK, et al.  (2008) Protein plasticity: a single amino acid substitution in the Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase generates protosta-13(17),24-dien-3beta-ol, a rearrangement product. Org Lett 10(12):2529-32
Craven RJ, et al.  (2007) Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51. J Biol Chem 282(50):36543-51
Warringer J and Blomberg A  (2006) Involvement of yeast YOL151W/GRE2 in ergosterol metabolism. Yeast 23(5):389-98
Davierwala AP, et al.  (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52
Mallory JC, et al.  (2005) Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae. Mol Cell Biol 25(5):1669-79
Ott RG, et al.  (2005) Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. Biochim Biophys Acta 1735(2):111-8
Parsons AB, et al.  (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9
Venkateswarlu K, et al.  (1998) NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrob Agents Chemother 42(7):1756-61
Gachotte D, et al.  (1997) A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme. Proc Natl Acad Sci U S A 94(21):11173-8
Bard M, et al.  (1993) Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans. Lipids 28(11):963-7
Taylor FR, et al.  (1983) Relationship between antifungal activity and inhibition of sterol biosynthesis in miconazole, clotrimazole, and 15-azasterol. Antimicrob Agents Chemother 23(4):515-21
Taylor FR, et al.  (1983) Requirement for a second sterol biosynthetic mutation for viability of a sterol C-14 demethylation defect in Saccharomyces cerevisiae. J Bacteriol 155(1):64-8
Karst F and Lacroute F  (1977) Ertosterol biosynthesis in Saccharomyces cerevisiae: mutants deficient in the early steps of the pathway. Mol Gen Genet 154(3):269-77