Other names published for DBF4: LSD7, DNA52, YDR052C
DBF4 LITERATURE TOPICS
- Curated Literature
- Genetics/Cell Biology
- Cell Cycle Phase Involved
- Cellular Location
- Function/Process
- Genetic Interactions
- Mutants/Phenotypes
- Regulation of
- Regulatory Role
- Nucleic Acid Information
- Gene Product Information
- Related Genes/Proteins
- Research Aids
- Genome-wide Analysis
- Proteome-wide Analysis
- Other Topics
- Additional Information
DBF4 - Genetic Interactions (28)
| Reference | Other Genes Addressed |
|---|---|
| Duch A, et al. (2011) A Dbf4 Mutant Contributes to Bypassing the Rad53-mediated Block of Origins of Replication in Response to Genotoxic Stress. J Biol Chem 286(4):2486-91 | |
| Mantiero D, et al. (2011) Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast.LID - 10.1038/emboj.2011.404 [doi] EMBO J () | |
| Chen YC and Weinreich M (2010) Dbf4 Regulates the Cdc5 Polo-like Kinase through a Distinct Non-canonical Binding Interaction. J Biol Chem 285(53):41244-54 | |
| Lopez-Mosqueda J, et al. (2010) Damage-induced phosphorylation of Sld3 is important to block late origin firing. Nature 467(7314):479-83 | |
| Ma L, et al. (2010) Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle 9(21):4399-410 | |
| Sheu YJ and Stillman B (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature 463(7277):113-7 | |
| Zegerman P and Diffley JF (2010) Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 467(7314):474-8 | |
| Miller CT, et al. (2009) Cdc7p-dbf4p regulates mitotic exit by inhibiting polo kinase. PLoS Genet 5(5):e1000498 | |
| Devault A, et al. (2008) Interplay between S-Cyclin-dependent Kinase and Dbf4-dependent Kinase in Controlling DNA Replication through Phosphorylation of Yeast Mcm4 N-Terminal Domain. Mol Biol Cell 19(5):2267-77 | |
| Matos J, et al. (2008) Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I. Cell 135(4):662-78 | |
| Ogi H, et al. (2008) The role of the Saccharomyces cerevisiae Cdc7-Dbf4 complex in the replication checkpoint. Gene 414(1-2):32-40 | |
| Sullivan M, et al. (2008) Cyclin-specific control of ribosomal DNA segregation. Mol Cell Biol 28(17):5328-36 | |
| Wan L, et al. (2008) Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast. Genes Dev 22(3):386-97 | |
| Warsi TH, et al. (2008) DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. Mol Biol Cell 19(10):4421-33 | |
| Dohrmann PR and Sclafani RA (2006) Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics 174(1):87-99 | |
| Davierwala AP, et al. (2005) The synthetic genetic interaction spectrum of essential genes. Nat Genet 37(10):1147-52 | |
| Pessoa-Brandao L and Sclafani RA (2004) CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. Genetics 167(4):1597-610 | |
| Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 | |
| Nougarede R, et al. (2000) Hierarchy of S-phase-promoting factors: yeast Dbf4-Cdc7 kinase requires prior S-phase cyclin-dependent kinase activation. Mol Cell Biol 20(11):3795-806 | |
| Dohrmann PR, et al. (1999) RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae. Genetics 151(3):965-77 | |
| Hardy CF, et al. (1997) mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p. Proc Natl Acad Sci U S A 94(7):3151-5 | |
| Lei M, et al. (1997) Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis. Genes Dev 11(24):3365-74 | |
| Tavormina PA, et al. (1997) Differential requirements for DNA replication in the activation of mitotic checkpoints in Saccharomyces cerevisiae. Mol Cell Biol 17(6):3315-22 | |
| Toyn JH, et al. (1995) Segregation of unreplicated chromosomes in Saccharomyces cerevisiae reveals a novel G1/M-phase checkpoint. Mol Cell Biol 15(10):5312-21 | |
| Jackson AL, et al. (1993) Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Mol Cell Biol 13(5):2899-908 | |
| Kitada K, et al. (1993) A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Mol Cell Biol 13(7):4445-57 | |
| Kitada K, et al. (1992) Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition. Genetics 131(1):21-9 | |
| Johnston LH and Thomas AP (1982) A further two mutants defective in initiation of the S phase in the yeast Saccharomyces cerevisiae. Mol Gen Genet 186(3):445-8 |





