CYC8/YBR112C Literature Guide Help

Other names published for CYC8: CRT8, SSN6, [OCT1+], [OCT], YBR112C

CYC8 - Genetic Interactions (42)

ReferenceOther Genes Addressed
Hang M and Smith MM  (2011) Genetic Analysis Implicates the Set3/Hos2 Histone Deacetylase in the Deposition and Remodeling of Nucleosomes Containing H2A.Z. Genetics 187(4):1053-66
Jaschke Y, et al.  (2011) Pleiotropic corepressors Sin3 and Ssn6 interact with repressor Opi1 and negatively regulate transcription of genes required for phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 285(2):91-100
Zheng J, et al.  (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Patel BK, et al.  (2009) The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion. Nat Cell Biol 11(3):344-9
Kobayashi Y, et al.  (2008) Identification of Tup1 and Cyc8 mutations defective in the responses to osmotic stress. Biochem Biophys Res Commun 368(1):50-55
Xia Z, et al.  (2008) Amino Acids Induce Peptide Uptake via Accelerated Degradation of CUP9, the Transcriptional Repressor of the PTR2 Peptide Transporter. J Biol Chem 283(43):28958-68
Wright CM, et al.  (2007) The Hsp40 molecular chaperone Ydj1p, along with the protein kinase C pathway, affects cell-wall integrity in the yeast Saccharomyces cerevisiae. Genetics 175(4):1649-64
Gandhi M, et al.  (2006) Four novel suppressors of gic1 gic2 and their roles in cytokinesis and polarized cell growth in Saccharomyces cerevisiae. Genetics 174(2):665-78
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Fragiadakis GS, et al.  (2004) Nhp6 facilitates Aft1 binding and Ssn6 recruitment, both essential for FRE2 transcriptional activation. EMBO J 23(2):333-42
Zhang Z and Reese JC  (2004) Redundant mechanisms are used by Ssn6-Tup1 in repressing chromosomal gene transcription in Saccharomyces cerevisiae. J Biol Chem 279(38):39240-50
Hwang CS, et al.  (2003) Ssn6, an important factor of morphological conversion and virulence in Candida albicans. Mol Microbiol 47(4):1029-43
Sertil O, et al.  (2003) Synergistic repression of anaerobic genes by Mot3 and Rox1 in Saccharomyces cerevisiae. Nucleic Acids Res 31(20):5831-7
Papamichos-Chronakis M, et al.  (2002) Cti6, a PHD domain protein, bridges the Cyc8-Tup1 corepressor and the SAGA coactivator to overcome repression at GAL1. Mol Cell 9(6):1297-305
Li B and Reese JC  (2001) Ssn6-Tup1 regulates RNR3 by positioning nucleosomes and affecting the chromatin structure at the upstream repression sequence. J Biol Chem 276(36):33788-97
Regnacq M, et al.  (2001) SUT1p interaction with Cyc8p(Ssn6p) relieves hypoxic genes from Cyc8p-Tup1p repression in Saccharomyces cerevisiae. Mol Microbiol 40(5):1085-96
Kastaniotis AJ, et al.  (2000) Roles of transcription factor Mot3 and chromatin in repression of the hypoxic gene ANB1 in yeast. Mol Cell Biol 20(19):7088-98
Kunoh T, et al.  (2000) Genetic characterization of rbt mutants that enhance basal transcription from core promoters in Saccharomyces cerevisiae. J Biochem 128(4):575-84
Li B and Reese JC  (2000) Derepression of DNA damage-regulated genes requires yeast TAF(II)s. EMBO J 19(15):4091-100
Limbach MP and Zitomer RS  (2000) The isolation and characterization of missense mutants in the general repressor protein Ssn6 of Saccharomyces cerevisiae. Mol Gen Genet 263(3):455-62
Basrai MA, et al.  (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9
Conlan RS, et al.  (1999) The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator. J Biol Chem 274(1):205-10
Shirra MK and Arndt KM  (1999) Evidence for the involvement of the Glc7-Reg1 phosphatase and the Snf1-Snf4 kinase in the regulation of INO1 transcription in Saccharomyces cerevisiae. Genetics 152(1):73-87
Desany BA, et al.  (1998) Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Genes Dev 12(18):2956-70
Friesen H, et al.  (1998) Spe3, which encodes spermidine synthase, is required for full repression through NRE(DIT) in Saccharomyces cerevisiae. Genetics 150(1):59-73
Kuchin S and Carlson M  (1998) Functional relationships of Srb10-Srb11 kinase, carboxy-terminal domain kinase CTDK-I, and transcriptional corepressor Ssn6-Tup1. Mol Cell Biol 18(3):1163-71
Gavin IM and Simpson RT  (1997) Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure. EMBO J 16(20):6263-71
Szeto L and Broach JR  (1997) Role of alpha2 protein in donor locus selection during mating type interconversion. Mol Cell Biol 17(2):751-9
Yang Z and Bisson LF  (1996) The SKS1 protein kinase is a multicopy suppressor of the snf3 mutation of Saccharomyces cerevisiae. Yeast 12(14):1407-19
Amillet JM, et al.  (1995) Positive and negative elements involved in the differential regulation by heme and oxygen of the HEM13 gene (coproporphyrinogen oxidase) in Saccharomyces cerevisiae. Curr Genet 28(6):503-11