CHO2/YGR157W Literature Guide Help

Other names published for CHO2: PEM1, phosphatidylethanolamine N-methyltransferase, YGR157W

CHO2 - Genetic Interactions (22)

ReferenceOther Genes Addressed
Sharifpoor S, et al.  (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801
Bilgin M, et al.  (2011) Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: a tool for monitoring PE metabolism. Biochim Biophys Acta 1811(12):1081-9
Chang HY, et al.  (2011) Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast. G3 (Bethesda) 1(3):197-208
Gulshan K and Moye-Rowley WS  (2011) Vacuolar import of phosphatidylcholine requires the ATP-binding cassette transporter Ybt1. Traffic 12(9):1257-68
Berthelet S, et al.  (2010) Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions. Genetics 185(3):1111-28
He X, et al.  (2010) Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks. Nat Genet 42(3):272-6
Garbarino J, et al.  (2009) Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death. J Biol Chem 284(45):30994-1005
Addinall SG, et al.  (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66
Federovitch CM, et al.  (2008) Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiae. Mol Biol Cell 19(10):4506-20
Frederick RL, et al.  (2008) Multiple pathways influence mitochondrial inheritance in budding yeast. Genetics 178(2):825-37
Han GS, et al.  (2008) An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth. J Biol Chem 283(29):20433-42
Riekhof WR, et al.  (2007) Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. J Biol Chem 282(51):36853-61
Boumann HA, et al.  (2006) Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. Mol Biol Cell 17(2):1006-17
Gohil VM, et al.  (2005) Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. J Biol Chem 280(42):35410-6
Pessi G, et al.  (2005) In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway. J Biol Chem 280(13):12461-6
Choi JY, et al.  (2004) Phosphatidylcholine and N-methylated phospholipids are nonessential in Saccharomyces cerevisiae. J Biol Chem 279(40):42321-30
Parsons AB, et al.  (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22(1):62-9
Tong AH, et al.  (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13
Huang D, et al.  (2002) Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. Mol Cell Biol 22(14):5076-88
Preitschopf W, et al.  (1993) Molecular cloning of the yeast OPI3 gene as a high copy number suppressor of the cho2 mutation. Curr Genet 23(2):95-101
McGraw P and Henry SA  (1989) Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis. Genetics 122(2):317-30
Summers EF, et al.  (1988) Saccharomyces cerevisiae cho2 mutants are deficient in phospholipid methylation and cross-pathway regulation of inositol synthesis. Genetics 120(4):909-22