CCC1/YLR220W Literature Guide Help

Other names published for CCC1: YLR220W

CCC1 - Genetic Interactions (18)

ReferenceOther Genes Addressed
Lee YJ, et al.  (2012) Sphingolipid signaling mediates iron toxicity. Cell Metab 16(1):90-6
Li L, et al.  (2012) A role for iron-sulfur clusters in the regulation of transcription factor Yap5-dependent high iron transcriptional responses in yeast. J Biol Chem 287(42):35709-21
Nishida K and Silver PA  (2012) Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway. PLoS Biol 10(2):e1001269
Li L, et al.  (2011) Yap5 protein-regulated transcription of the TYW1 gene protects yeast from high iron toxicity. J Biol Chem 286(44):38488-97
Lin H, et al.  (2011) Genetic and Biochemical Analysis of High Iron Toxicity in Yeast: IRON TOXICITY IS DUE TO THE ACCUMULATION OF CYTOSOLIC IRON AND OCCURS UNDER BOTH AEROBIC AND ANAEROBIC CONDITIONS. J Biol Chem 286(5):3851-62
Li L, et al.  (2010) Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport. J Biol Chem 285(14):10232-42
Lin H, et al.  (2009) Gain-of-function mutations identify amino acids within transmembrane domains of the yeast vacuolar transporter Zrc1 that determine metal specificity. Biochem J 422(2):273-83
Lin H, et al.  (2008) A single amino Acid change in the yeast vacuolar metal transporters zrc1 and cot1 alters their substrate specificity. J Biol Chem 283(49):33865-73
Devasahayam G, et al.  (2007) Golgi Manganese Transport Is Required for Rapamycin Signaling in Saccharomyces cerevisiae. Genetics 177(1):231-8
De Domenico I, et al.  (2006) Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. EMBO J 25(22):5396-404
Kumanovics A, et al.  (2006) YKE4 (YIL023C) encodes a bidirectional zinc transporter in the endoplasmic reticulum of Saccharomyces cerevisiae. J Biol Chem 281(32):22566-74
Chen OS, et al.  (2004) Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis. J Biol Chem 279(28):29513-8
Li L and Kaplan J  (2004) A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. J Biol Chem 279(32):33653-61
Tuttle MS, et al.  (2003) A dominant allele of PDR1 alters transition metal resistance in yeast. J Biol Chem 278(2):1273-80
Chen OS and Kaplan J  (2000) CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. J Biol Chem 275(11):7626-32
Lapinskas PJ, et al.  (1996) The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions. Mol Microbiol 21(3):519-28
Pozos TC, et al.  (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41
Fu D, et al.  (1994) Sequence, mapping and disruption of CCC1, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants. Yeast 10(4):515-21