AFT1/YGL071W Literature Guide Help

Other names published for AFT1: RCS1, YGL071W

AFT1 - Genetic Interactions (26)

ReferenceOther Genes Addressed
Qi J, et al.  (2012) Metal-sensing transcription factors Mac1p and Aft1p coordinately regulate vacuolar copper transporter CTR2 in Saccharomyces cerevisiae. Biochem Biophys Res Commun 423(2):424-8
Castells-Roca L, et al.  (2011) The oxidative stress response in yeast cells involves changes in the stability of Aft1 regulon mRNAs. Mol Microbiol 81(1):232-48
Hoffmann B, et al.  (2011) The multidomain thioredoxin-monothiol glutaredoxins represent a distinct functional group. Antioxid Redox Signal 15(1):19-30
Kumar C, et al.  (2011) Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control. EMBO J 30(10):2044-56
Toesca I, et al.  (2011) Cryptic transcription mediates repression of subtelomeric metal homeostasis genes. PLoS Genet 7(6):e1002163
Ayer A, et al.  (2010) The critical role of glutathione in maintenance of the mitochondrial genome. Free Radic Biol Med 49(12):1956-68
Berthelet S, et al.  (2010) Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions. Genetics 185(3):1111-28
Pujol-Carrion N and de la Torre-Ruiz MA  (2010) Glutaredoxins Grx4 and Grx3 of Saccharomyces cerevisiae Play a Role in Actin Dynamics through Their Trx Domains, Which Contributes to Oxidative Stress Resistance. Appl Environ Microbiol 76(23):7826-7835
Zheng J, et al.  (2010) Epistatic relationships reveal the functional organization of yeast transcription factors. Mol Syst Biol 6():420
Jeong MY, et al.  (2009) A novel function of Aft1 in regulating ferrioxamine B uptake: Aft1 modulates Arn3 ubiquitination in Saccharomyces cerevisiae. Biochem J 422(1):181-91
Sideri TC, et al.  (2009) Methionine sulphoxide reductases protect iron-sulphur clusters from oxidative inactivation in yeast. Microbiology 155(Pt 2):612-23
Andrew AJ, et al.  (2008) Posttranslational regulation of the scaffold for Fe-S cluster biogenesis, Isu. Mol Biol Cell 19(12):5259-66
Irazusta V, et al.  (2008) Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins. Free Radic Biol Med 44(9):1712-1723
Kumanovics A, et al.  (2008) Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis. J Biol Chem 283(16):10276-86
Dubacq C, et al.  (2006) Role of the iron mobilization and oxidative stress regulons in the genomic response of yeast to hydroxyurea. Mol Genet Genomics 275(2):114-24
Ojeda L, et al.  (2006) Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae. J Biol Chem 281(26):17661-9
Yang M, et al.  (2006) The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2. EMBO J 25(8):1775-83
Courel M, et al.  (2005) Direct activation of genes involved in intracellular iron use by the yeast iron-responsive transcription factor Aft2 without its paralog Aft1. Mol Cell Biol 25(15):6760-71
Measday V, et al.  (2005) Systematic yeast synthetic lethal and synthetic dosage lethal screens identify genes required for chromosome segregation. Proc Natl Acad Sci U S A 102(39):13956-61
Li L and Kaplan J  (2004) A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. J Biol Chem 279(32):33653-61
Blaiseau PL, et al.  (2001) Aft2p, a novel iron-regulated transcription activator that modulates, with Aft1p, intracellular iron use and resistance to oxidative stress in yeast. J Biol Chem 276(36):34221-6
Garcia MG, et al.  (2001) Isolation of a Candida albicans gene, tightly linked to URA3, coding for a putative transcription factor that suppresses a Saccharomyces cerevisiae aft1 mutation. Yeast 18(4):301-11
Rutherford JC, et al.  (2001) A second iron-regulatory system in yeast independent of Aft1p. Proc Natl Acad Sci U S A 98(25):14322-7
Chen OS and Kaplan J  (2000) CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. J Biol Chem 275(11):7626-32
Philpott CC, et al.  (1998) Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast. EMBO J 17(17):5026-36
Casas C, et al.  (1997) The AFT1 transcriptional factor is differentially required for expression of high-affinity iron uptake genes in Saccharomyces cerevisiae. Yeast 13(7):621-37